SU743998A1 - Method of preparing 5-methylenethiazolidinediones-2,4- or their derivatives - Google Patents

Method of preparing 5-methylenethiazolidinediones-2,4- or their derivatives Download PDF

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Publication number
SU743998A1
SU743998A1 SU782584573A SU2584573A SU743998A1 SU 743998 A1 SU743998 A1 SU 743998A1 SU 782584573 A SU782584573 A SU 782584573A SU 2584573 A SU2584573 A SU 2584573A SU 743998 A1 SU743998 A1 SU 743998A1
Authority
SU
USSR - Soviet Union
Prior art keywords
derivatives
alkyl
formula
methylenethiazolidinediones
preparing
Prior art date
Application number
SU782584573A
Other languages
Russian (ru)
Inventor
Иосиф Дмитриевич Комарица
Original Assignee
Львовский государственный медицинский институт
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Львовский государственный медицинский институт filed Critical Львовский государственный медицинский институт
Priority to SU782584573A priority Critical patent/SU743998A1/en
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Publication of SU743998A1 publication Critical patent/SU743998A1/en

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  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Description

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Claims (2)

Формула изобретенияClaim 1. Способ получения 5-метилентиазолпдиндионов-2,4 или их производных общей формулы где X — кислород, азот или сера;1. The method of obtaining 5-methylentiazolpinedione-2,4 or their derivatives of the General formula where X is oxygen, nitrogen or sulfur; Υ — кислород или сера;Υ - oxygen or sulfur; R— водород, алкил, арил;R is hydrogen, alkyl, aryl; R'— алкил, арил;R'is alkyl, aryl; R— водород, низший алкил, путем конденсации производного тизолидина с карбонильным соединением в присутствии первичного амина в качестве катализатора, отличающийся тем, что, с целью упрощения технологии процесса и расширения сырьевой базы, соединение формулы где X, Υ и R имеют указанные значения, подвергают взаимодействию с карбонильным соединением формулыR is hydrogen, lower alkyl, by condensation of a derivative of tizolidine with a carbonyl compound in the presence of a primary amine as a catalyst, characterized in that, in order to simplify the process technology and expand the raw material base, the compound of the formula where X, Υ and R have the indicated meanings, interaction with a carbonyl compound of the formula R-C-R*R-C-R * И О где R и R' имеют указанные значения, в среде воды или органического растворителя.And O where R and R 'have the indicated meanings in an environment of water or an organic solvent. 2. Способ по π. 1, о т л и ч а ю щ и й с я тем, что в качестве органического растворителя используют уксусную кислоту.2. The method according to π. 1, with the fact that acetic acid is used as an organic solvent.
SU782584573A 1978-02-20 1978-02-20 Method of preparing 5-methylenethiazolidinediones-2,4- or their derivatives SU743998A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SU782584573A SU743998A1 (en) 1978-02-20 1978-02-20 Method of preparing 5-methylenethiazolidinediones-2,4- or their derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SU782584573A SU743998A1 (en) 1978-02-20 1978-02-20 Method of preparing 5-methylenethiazolidinediones-2,4- or their derivatives

Publications (1)

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SU743998A1 true SU743998A1 (en) 1980-06-30

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SU782584573A SU743998A1 (en) 1978-02-20 1978-02-20 Method of preparing 5-methylenethiazolidinediones-2,4- or their derivatives

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2522449C1 (en) * 2013-03-14 2014-07-10 Общество с ограниченной ответственностью "Лечебное питание" Agent possessing antiproloferative and antimetastatic action for treating malignant diseases

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2522449C1 (en) * 2013-03-14 2014-07-10 Общество с ограниченной ответственностью "Лечебное питание" Agent possessing antiproloferative and antimetastatic action for treating malignant diseases

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