Московский государственный университет им.М.В.Ломоносова
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Московский государственный университет им.М.В.ЛомоносоваfiledCriticalМосковский государственный университет им.М.В.Ломоносова
Priority to SU2704355/05ApriorityCriticalpatent/SU731750A1/en
Application grantedgrantedCritical
Publication of SU731750A1publicationCriticalpatent/SU731750A1/en
FIELD: biotechnology. SUBSTANCE: affine adsorbent has albumin covalently immobilized on polymeric carrier and water. Adsorbent has 10-40 weight % copolymer of albumin acylated with unsaturated acid chloroanhydride as immobilized albumin, N-vinylpyrrolidone and bifunctional cross-linking agent. To produce adsorbent albumin acylated with unsaturated acid chloroanhydride (5-20 weight%) is polymerized in water with 5-20 weight % a mixture consisting of N-vinylpyrrolidone and bifunctional cross-linking agent at weight ratio of monomers in mixture and cross-linking agent = (9-7):(1-3). EFFECT: increased capacity and heme-biocompatibility of adsorbent, decreased hypoproteinemia.
SU2704355/05A1978-12-211978-12-21Affine adsorbent for removal of bilirubin and other toxicants from blood and a method of its producing
SU731750A1
(en)