SU625694A1

SU625694A1 - Method of diagnosis of eye orbit and body tumors

Info

Publication number: SU625694A1
Application number: SU742070890A
Authority: SU
Inventors: Олег Александрович Акаткин
Original assignee: Краснодарский Краевой Клинический Онкологический Диспансер
Priority date: 1974-10-28
Filing date: 1974-10-28
Publication date: 1978-09-30

Description

1one

Изобретение относитс к области радиационной медицины и может быть использовано при диагностике злокачественных опухолей орбиты и тела глаза.The invention relates to the field of radiation medicine and can be used in the diagnosis of malignant tumors of the orbit and body of the eye.

Известен способ диагностики опухолей орбиты и тела глаза путем введени радиоактивного препарата и регистрации излучени Вавилова-Черенкова.A known method for diagnosing tumors of the orbit and body of the eye by injecting a radioactive preparation and registering Vavilov-Cherenkov radiation.

Недостатком известного способа вл етс низка чувствительность и невозможность определени зоны расположени онухоли относительно центральной оси зрачка глаза.The disadvantage of this method is low sensitivity and the impossibility of determining the location of onucholi relative to the central axis of the pupil of the eye.

Цель изобретени - повысить чувствительность способа и определить зону расположени онухоли относительно центральной оси зрачка глаза.The purpose of the invention is to increase the sensitivity of the method and to determine the area of onukholi relative to the central axis of the pupil of the eye.

Эта цель достигаетс тем, что на объект исследовани после введени радиоактивного препарата воздействуют магнитным нолем с напр жени ми от 1 до 15 кэ, регистрацию излучени Вавилова-Черенкова производ т до и после воздействи магнитным полем и по разнице величин излучени диагностируют опухоли относительно центральной оси зрачка.This goal is achieved by the fact that after the introduction of a radioactive drug the magnetic object is applied with voltages from 1 to 15 ke, the Vavilov-Cherenkov radiation is recorded before and after exposure to a magnetic field and the difference of the radiation values is diagnosed by tumors relative to the central axis of the pupil .

На чертеже изображена схема глаза с указанием зрачка 3, зон расположени опухолей О и О , их осей А-Л и В-5, точки размен1,ени детектора Д, полюсов The drawing shows a diagram of the eye with the indication of the pupil 3, the areas of the O and O tumors, their axes A-L and B-5, the exchange points 1, the detector D, the poles

электромагнита Л и S и линий напр женности магнитного нол .electromagnet L and S and lines of magnetic magnetic intensity.

Способ осуществл ют следующим образо .м.The method is carried out as follows.

При отсутствии магнитного нол электроны из зон опухолей О и О движутс во все стороны изотропно и по направлению своего двилчеинн испускают излучение Вавилова-Черенкова, при этом:In the absence of a magnetic field, electrons from the O and O tumor zones move in all directions isotropically and emit Vavilov-Cherenkov radiation in their direction, and the dililcheyns emit:

1)если опухоль О располагаетс на оси Л-Л, в нределах зоны пр мой вндимости зрачка и детектора Д, то регистрируетс максимальна интенсивность излучени ;1) if the tumor O is located on the axis LL, within the limits of the area of direct pupil viscosity and detector D, then the maximum radiation intensity is recorded;

2)при исследовапии опухоли, расположенной в зоне Oi, нзлученне Вавнлова-Черенкова распростран етс , преимущественно , по оси В-В. перпендикул рно к центральной оси зрачка Л-Л и ири равной активности содер ащегос в ней фосфора (Рз2) интенсивность излучени , регистрируема детектором Д, будет ннже, чем в первом случае.2) when investigating a tumor located in the Oi zone, the Vavnlov-Cherenkov incident propagates mainly along the B-B axis. perpendicular to the central axis of the pupil L-L and iri of equal activity containing phosphorus (Pc2) in it, the intensity of radiation recorded by detector D will be lower than in the first case.

Claims

The imposition of the magnetic field H + polarity on the study zone will lead to the fact that for the first case (tumor in zone O), the intensity of Vavilov-Cherenkov radiation registered by the detector decreases, since electrons moving along the LL axis deviate from this axis in storiou In axis bb. In the second case, the electrons moving away from the tumor O along the axis B-B, deviate from it towards the pupil (towards the axis A-L) and the intensity of radiation detected by detector D will increase. When the polarity of the magnetic field on the H-electrons changes in both cases, they are deflected in opposite directions. At the same time, by adjusting the magnitude of the H + floor intensity in the range, for example, from 1 to 15 Ke, you can change the shape of the trajectories of electrons or other charged particles emitted by the active drug contained in the tumor, with their predominant focusing in the visibility zone of the pupil (detector ). Thus, by changing the polarity of the magnetic field at a given value of its intensity H +, for example, at 9 ke, the sensitivity of the method can be increased by increasing the intensity of the detected Vavilov-Cherenkov radiation by adjusting the trajectories of electrons with their preferred direction toward the pupil (detector) at off-center location of the tumor, as well as determine the area of the tumor by comparing the magnitude of the signal recorded by the detector when applying a magitic field to a different Lness with a signal registered in the absence of a magnetic field. The table shows the results of studies of the influence of the magnetic field of H 9 ke intensity on the brightness of a transparent medium with a different orientation of the electron beam with respect to the observer. Table It follows from the table that the sensitivity of the method in the diagnosis of malignant tumors located off-center to the pupil can be increased by 80% only due to the application of a magnetic field, but compared to measurements in its absence. The proposed method allows to increase the sensitivity and determine the location of the tumor relative to the central axis of the pupil of the eye. The invention of a method for diagnosing tumors of the orbit and body of the eye by administering a radioactive preparation and recording Vavilov-Cherenkov radiation, characterized in that, in order to increase the sensitivity of the method and determine the area of the tumor relative to the central axis of the pupil of the eye, the object under investigation is magnetic after the radioactive preparation. a field with voltages from 1 to 15 ke, the Vavilov-Cherenkov radiation is recorded before and after exposure to a magnetic field and the difference in magnitude zlucheni diagnosed tumor relative to the central axis of the pupil.