SU408950A1 - METHODS OF OBTAINING COMPOUNDS OF THE TIOPHIAI SERIES - Google Patents
METHODS OF OBTAINING COMPOUNDS OF THE TIOPHIAI SERIESInfo
- Publication number
- SU408950A1 SU408950A1 SU1743922A SU1743922A SU408950A1 SU 408950 A1 SU408950 A1 SU 408950A1 SU 1743922 A SU1743922 A SU 1743922A SU 1743922 A SU1743922 A SU 1743922A SU 408950 A1 SU408950 A1 SU 408950A1
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- series
- tiophiai
- methods
- obtaining compounds
- compounds
- Prior art date
Links
Landscapes
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Description
1one
Изобретение усовершенствует снособ получени соединений р да тиофаиа (тетрагндроТ1гофена ), которые нредставл ют интерес как физиологически активные соедииеии , промежуточные продукты в органическом снитезе, моде.чьиые соединени дл из чег1н состава нефт ных фракннй и добавки, улучшающие качество нефтепродуктов.The invention will improve the preparation of compounds of the thiofaia (tetragndroT1gofen) series, which are of interest as physiologically active compounds, intermediate products in organic synthesis, modular compounds for petroleum composition and additives that improve the quality of petroleum products.
Извесген снособ получени соединеннй р да тнофаиа гидрированием соединений р да тиофена с нсиользованием налладневого катализатора . Выход целевого нродукта 60-70%.Izvesgen is a method for producing a connected datonnate by hydrogenating compounds of the thiophene series using a bulk catalyst. The yield of the target product 60-70%.
При осун ествленнн способа возппкает необходимость использовани дорогосто ш.нх каталнзаторов, которые невозможно регенерировать , и применени газообразного водорода . Выход целевого нродукта относительноWith the implementation of the method, it is necessary to use expensive sh.nh catalysts that cannot be regenerated and to use hydrogen gas. The yield of the target product relative to
nCBlilCOK.nCBlilCOK.
С целью унрощепн технологического процесса в качестве гидрируюн;его агента используют гндридсилан в кислой среде.For the purpose of the technological process, as a hydroscopic, its agent is used gndridsilan in an acidic environment.
Процесс предпочтптельпо ведут при температуре 50-70°С. Выход целевого продукта составл ет 80-85% от теоретического.The process is preferably carried out at a temperature of 50-70 ° C. The yield of the target product is 80-85% of theoretical.
Пример 1. Получение 2,5-диметилтиофаиа ,Example 1. Getting 2,5-dimethylthiofia,
Смесь 2,24 г (0,02 моль) 2,5-днметнлтнофена , 5,26 г (0,045 ноль триэтилсилана и 16,41 г (0,14 .моль трнфторуксусной кислоты нагревают 20 час нри 60°С, нейтрализуют носле охлаждени раствором соды, экстрагируют эфиром , высушивают над MgSO. lleperoHKoii выдел ют 1,95 г (выход (,) 2,5-днметнлтиофана , т, К1Ш. НО-142°С, т 1,4768.A mixture of 2.24 g (0.02 mol) of 2.5-dnmetnltofen, 5.26 g (0.045 nil of triethylsilane and 16.41 g (0.14. Mol of trfluoroacetic acid is heated for 20 hours at 60 ° C, neutralized by cooling with a solution soda, extracted with ether, dried over MgSO4. lleperoHKoii separated 1.95 g (yield (,) 2,5-dn-mntiofana, t, K1SH. HO-142 ° C, t 1.4768.
Пример 2. Получение 2-л1етнлт1юфана.Example 2: Preparation of 2-ml.
Смесь 0,23 г (0,0023 моль 2-метилтиофана, 0,53 г (0,0046 моль} трнэтилсилаиа н 2,17 г. (0,019 моль трифторуксусной кислоты нагревают при 50°С 15 час. Смесь обрабатывают, как в нрн.мере 1, перегонкой нолучают 0,19 г (выход ,) 2-метн.1тнофана, т KIHI. 130- 133°С, 11.22 l,4896.A mixture of 0.23 g (0.0023 mol of 2-methylthiophane, 0.53 g (0.0046 mol) of triethylsilane and 2.17 g (0.019 mol of trifluoroacetic acid is heated at 50 ° C for 15 h. The mixture is treated as in nrn Measure 1, by distillation, 0.19 g (yield) of 2-metn. tnofan, t KIHI 130-133 ° C, 11.22 l, 4896.
П р е д м е т н з о б р е т е н н JtPRIORITY OF THE ABSTRACT Jt
Claims (2)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU1743922A SU408950A1 (en) | 1972-02-02 | 1972-02-02 | METHODS OF OBTAINING COMPOUNDS OF THE TIOPHIAI SERIES |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU1743922A SU408950A1 (en) | 1972-02-02 | 1972-02-02 | METHODS OF OBTAINING COMPOUNDS OF THE TIOPHIAI SERIES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU408950A1 true SU408950A1 (en) | 1973-11-30 |
Family
ID=20501968
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU1743922A SU408950A1 (en) | 1972-02-02 | 1972-02-02 | METHODS OF OBTAINING COMPOUNDS OF THE TIOPHIAI SERIES |
Country Status (1)
| Country | Link |
|---|---|
| SU (1) | SU408950A1 (en) |
-
1972
- 1972-02-02 SU SU1743922A patent/SU408950A1/en active
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