SU393267A1 - METHOD FOR OBTAINING AMINOMETHYL DERIVATIVE - Google Patents
METHOD FOR OBTAINING AMINOMETHYL DERIVATIVEInfo
- Publication number
- SU393267A1 SU393267A1 SU1652365A SU1652365A SU393267A1 SU 393267 A1 SU393267 A1 SU 393267A1 SU 1652365 A SU1652365 A SU 1652365A SU 1652365 A SU1652365 A SU 1652365A SU 393267 A1 SU393267 A1 SU 393267A1
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- obtaining
- aminomethyl derivative
- nitrophenol
- aminomethyl
- derivative
- Prior art date
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Description
Изобретение относитс к способу Получени нового нитрофенольного основани Манниха .The invention relates to a process for the preparation of a new nitrophenolic base mannich.
Известно применение бисдиалкиламинометанов в качестве аминолирующего агента при получении фенольного основани Манниха. Однако аналогичное аминолирование других соединений, содержащих реакционноспособный атом водорода, в том числе нитрофенола , в литературе не описано.It is known to use bis-dialkylaminomethanes as an aminolating agent in the preparation of the phenolic base of mannich. However, similar aminolation of other compounds containing a reactive hydrogen atom, including nitrophenol, is not described in the literature.
Предлагаемый способ получени аминометильного производного п-нитрофенола заключаетс в том, что л-нитрофенол конденсируют с бисдиалкиламинометаном в безводной среде с дальнейшим выделением целевого продукта известным способом.The proposed method for the preparation of the aminomethyl p-nitrophenol derivative consists in that l-nitrophenol is condensed with bis-alkylaminomethane in an anhydrous medium, with a further release of the target product in a known manner.
Пример. В колбу, снабженную затвором, термометром и нисход щим холодильником.Example. In a flask equipped with a shutter, a thermometer and a downward cooler.
загружают 20 г п-пптрофенола и 22,5 г бисдпэтиламинометана и при перемешивании нагревают 2 час на вод ной бане, отгон ют диэтиламин (6 г), оставшийс в колбе 2-диэтиламинометил-4-нитрофенол очищают ацетоном, Выход 30 г (93,1%), т. пл. 127-128 С.20 g of p-pptrofenol and 22.5 g of bisdipethylaminomethane are loaded and heated with a stirring for 2 hours in a water bath, diethylamine (6 g) is distilled off, the 2-diethylaminomethyl-4-nitrophenol remaining in the flask is purified with acetone. 30 g yield 1%), t. Pl. 127-128 C.
Найдено, %: С 58,74; Н 6,41; N 12,27.Found,%: C 58.74; H 6.41; N 12.27.
Вычислено, %: С 58,91; Н 7,19; N 12,49.Calculated,%: C 58.91; H 7.19; N 12.49.
Предмет изобретени Subject invention
Способ получени аминометильного производного п-нитрофенола, отличающийс тем, что л-нитрофенол кондепсируют с бисдиалкиламинометаном в безводной среде с последующим выделением целевого продукта известным способом.A method for producing an aminomethyl p-nitrophenol derivative, characterized in that l-nitrophenol is condensed with bis-alkylaminomethane in an anhydrous medium, followed by isolation of the target product by a known method.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU1652365A SU393267A1 (en) | 1971-04-26 | 1971-04-26 | METHOD FOR OBTAINING AMINOMETHYL DERIVATIVE |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU1652365A SU393267A1 (en) | 1971-04-26 | 1971-04-26 | METHOD FOR OBTAINING AMINOMETHYL DERIVATIVE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU393267A1 true SU393267A1 (en) | 1973-08-10 |
Family
ID=20474009
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU1652365A SU393267A1 (en) | 1971-04-26 | 1971-04-26 | METHOD FOR OBTAINING AMINOMETHYL DERIVATIVE |
Country Status (1)
| Country | Link |
|---|---|
| SU (1) | SU393267A1 (en) |
-
1971
- 1971-04-26 SU SU1652365A patent/SU393267A1/en active
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