SU1756320A1 - 2,3,11,12-difurasano-1,4,7,10,13,16-hexaoxacyclooctadecadien- 2,11 - Google Patents

Abstract

The invention relates to the preparation of a heterocyclic compound, in particular a 2.3 11,12-difurazano-1,47,10,13,16-hexa-hydroxy acid, which can be used as an interfacial catalyst. The purpose is to create a new class of heterocyclic compounds. Synthesis is carried out by reaction 3 , 4-dihydroxyfurazane with 2,2, -dichlorodiethyl ether in alkaline condition in butanol and water at 60 ° C. Yield 7%, gross f la Ci2Hi6N /) 08

Description

sh

with

The invention relates to a new class of heterocyclic compounds, namely, to a new heterocyclic system - 2,3,11,12-difurazano-1 4 7,10,13,16-hexa-x-acyclooctzdecadiene 211 of the formula:

((HF DT0 QYHv

V4 „olg

H-Okory who can be used as a catalyst for heterophase reactions (phase-transfer catalyst)

2,3,11,12-Difurzano-1,4,7,10,13,1b-hexa-xoxacyclo-odecadien-2,11 is a representative of compounds that do not simultaneously encounter a sequence of atoms and bonds in the annelated tricyclic system comprising two 1,2,5-okadazhiazolny (furazan) cycles and

1,4,7,13,16-hexaoxacyclooctadecadien 2, cycle 11

The aim of the invention is a new half-hgterocyclic system containing both furazanose and 1,4,7,10,13,16-hexa-oxacycloooctadecade — n-2,11-th cycle

The goal is achieved by a new compound - 2,3,11,12-difurazano-1,4,7,10,13,1b-hexa-x-acyclo-octadecadmen-2,11-m

The compound of the indicated formula is obtained by reacting 3,4-dihydroxyfrazan with dichlsethylether in the presence of alkali.

Example RJ 1.02 g (10 mmol) of 3,4-dihydroxyburazan is dissolved in a mixture of 20 ml of n-butanol and 0.5 ml of water and 0.4 g (10 mmol) of NaOH is added, heated to 60 ° C and a solution of 0.71 g (5 mmol) of dichlorodiethyl ether in 10 ml of n-butanol is added dropwise. Then a solution of 0.4 g (10 mmol) of NaOH in 1 ml of water is added and again added dropwise

a solution of 0.71 g (5 mmol) of dichlorodiethyl ether in 10 ml of n-butanol. Heat the reaction mixture to a boil. After cooling, 1-2 ml of concentrated hydrochloric acid are added and evaporated in a water jet vacuum, ca. The product is extracted from the residue by extraction. Obtain 0.12 g (7%) of the target substance. IR spectrum (in KBG, V,) .2980,1610,1575,1400,1290,1185,1160, 1120, 1030, 910. Mass spectrum, m / z: 344 (L / G) (calculated - 344) . PMR spectrum (d, ppm): 3.7-4.4. .. "E%

Found,%: C 41.21; H 4.83; T 16.17.

C12H16N408.

Claims (1)

Calculated,%: C, 41.86; H 4.65; N 16.28. Invention Formula 2,3,11,12-Difurazano-1,4,7,10,13,16-hexa-oxacyclo-octade decadien-2.11 of formula I ((G4 VO Oh HGP p UU P No about