SU1607348A1 - 7-(3-phenylpropenoyloxy)-4'-fluoroisiflavone having hypotensive activity - Google Patents

7-(3-phenylpropenoyloxy)-4'-fluoroisiflavone having hypotensive activity

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Publication number
SU1607348A1
SU1607348A1 SU4657749/04A SU4657749A SU1607348A1 SU 1607348 A1 SU1607348 A1 SU 1607348A1 SU 4657749/04 A SU4657749/04 A SU 4657749/04A SU 4657749 A SU4657749 A SU 4657749A SU 1607348 A1 SU1607348 A1 SU 1607348A1
Authority
SU
USSR - Soviet Union
Prior art keywords
hypotensive activity
phenylpropenoyloxy
fluoroisiflavone
new
fluoroisoflavone
Prior art date
Application number
SU4657749/04A
Other languages
Russian (ru)
Inventor
М.С. Лукьянчиков
В.П. Хиля
М.Н. Ивашев
Г.И. Лукьянчикова
Original Assignee
Пятигорский фармацевтический институт
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Пятигорский фармацевтический институт filed Critical Пятигорский фармацевтический институт
Priority to SU4657749/04A priority Critical patent/SU1607348A1/en
Application granted granted Critical
Publication of SU1607348A1 publication Critical patent/SU1607348A1/en

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Abstract

FIELD: heterocyclic compounds, can be used in medicine. SUBSTANCE: the synthesis is effected by reacting 7-oxy-4-fluoroisoflavone with cinnamic acid chloride in pyridine on heating (1.5 hr) followed by treatment of the reaction mixture with an aqueous solution of acetic acid. The yield 75.5%, mp 212-213 C, the empirical formula: CHFO. The hypotensive activity of the new compound when injected subcutaneously (100 mg/kg) is by 2 times higher than of theobromine and by 1.6 higher than that of the structural analogues by the 60th minute. EFFECT: new more active compounds of said class. 1 tbl
SU4657749/04A 1989-03-02 1989-03-02 7-(3-phenylpropenoyloxy)-4'-fluoroisiflavone having hypotensive activity SU1607348A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SU4657749/04A SU1607348A1 (en) 1989-03-02 1989-03-02 7-(3-phenylpropenoyloxy)-4'-fluoroisiflavone having hypotensive activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SU4657749/04A SU1607348A1 (en) 1989-03-02 1989-03-02 7-(3-phenylpropenoyloxy)-4'-fluoroisiflavone having hypotensive activity

Publications (1)

Publication Number Publication Date
SU1607348A1 true SU1607348A1 (en) 1994-09-30

Family

ID=60521928

Family Applications (1)

Application Number Title Priority Date Filing Date
SU4657749/04A SU1607348A1 (en) 1989-03-02 1989-03-02 7-(3-phenylpropenoyloxy)-4'-fluoroisiflavone having hypotensive activity

Country Status (1)

Country Link
SU (1) SU1607348A1 (en)

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