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Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
FIELD: heterocyclic compounds, can be used in medicine. SUBSTANCE: the synthesis is effected by reacting 7-oxy-4-fluoroisoflavone with cinnamic acid chloride in pyridine on heating (1.5 hr) followed by treatment of the reaction mixture with an aqueous solution of acetic acid. The yield 75.5%, mp 212-213 C, the empirical formula: CHFO. The hypotensive activity of the new compound when injected subcutaneously (100 mg/kg) is by 2 times higher than of theobromine and by 1.6 higher than that of the structural analogues by the 60th minute. EFFECT: new more active compounds of said class. 1 tbl
SU4657749/04A1989-03-021989-03-027-(3-phenylpropenoyloxy)-4'-fluoroisiflavone having hypotensive activity
SU1607348A1
(en)
Process for the production of hydroximethyl-(methylene-cyclopentyl)-purines and pirimidines, their medically usable salts, and of medical preparations containing them