SU1563696A1 - Radioprotector - Google Patents
Radioprotector Download PDFInfo
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- SU1563696A1 SU1563696A1 SU792830742A SU2830742A SU1563696A1 SU 1563696 A1 SU1563696 A1 SU 1563696A1 SU 792830742 A SU792830742 A SU 792830742A SU 2830742 A SU2830742 A SU 2830742A SU 1563696 A1 SU1563696 A1 SU 1563696A1
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- SU
- USSR - Soviet Union
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- skin
- radioprotector
- increase
- relates
- solution
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Изобретение относитс к медицине и касаетс средства дл защиты кожных покровов от воздействи ионизирующей радиации. Цель изобретени - повышение радиозащитного действи на кожу. Предлагаемый радиопротектор позвол ет повысить радиозащитное действие на кожу за счет применени 2,6-диметил-3,5-диэтоксикарбонил-1,4-дигидропиридина. Известное вещество вл етс органическим соединением.The invention relates to medicine and relates to a means for protecting the skin from the effects of ionizing radiation. The purpose of the invention is to increase the radioprotective effect on the skin. The proposed radioprotector makes it possible to increase the radioprotective effect on the skin through the use of 2,6-dimethyl-3,5-diethoxycarbonyl-1,4-dihydropyridine. The known substance is an organic compound.
Description
Изобретение относитс к медицине, в частности к средствам дл защиты кожных покровов от воздействи ионизирующей радиации.The invention relates to medicine, in particular to means for protecting the skin from exposure to ionizing radiation.
Цель изобретени - повышение ра- диозашитного действи на кожу.The purpose of the invention is to increase the radioactivity effect on the skin.
Примен ют 5%-ный масл ный раствор, причем 1 мл раствора содержит 50 мг основного вещества. Раствор готов т в климатических учреждени х ex tern- pore и используют в течение 15-20 ч с момента приготовлени . Приготовленный раствор за 15-20 мин до рентге- нооблучени или радиологической процедуры с помощью пластмассовой лопаточки или палочки нанос т на участки кожи, подлежащие облучению, и распредел ют ровным слоем. Расход препарата производитс из расчета 1 мл раствора н 1 дм1 кожи.A 5% oily solution is used, with 1 ml of the solution containing 50 mg of the basic substance. The solution is prepared ex climatically in climate institutions and used within 15-20 hours from the time of preparation. The prepared solution is applied 15-20 minutes before the X-ray irradiation or radiological procedure with a plastic spatula or stick is applied to the skin to be irradiated and evenly distributed. The consumption of the preparation is based on 1 ml of a solution of n 1 dm1 of skin.
Предлагаемый радиопротектор обладает низкой токсичностью ( 30000 мг/кг в опытах на белых мытах при пероральном введении), не раздражает кожу, более стабилен чем ДМСО, может примен тьс с другими лечебными средствами.The proposed radioprotector has low toxicity (30,000 mg / kg in experiments on white myta when administered orally), does not irritate the skin, is more stable than DMSO, and can be used with other therapeutic agents.
При облучении в эритемных дозах (2000Р при рентгеновском облучении и 6000 Р при /з-облучении длительность периода эритемы сокращаетс в -/ раза, а длительность т желой эритемной реакции в Зраза.When irradiated in erythemal doses (2000P under x-ray irradiation and 6000 R under / 3-irradiation), the duration of the period of erythema is reduced by - / times, and the duration of the severe erythemal reaction in Zraz.
Полностью предотвращаетс десква- маци , вызванна /j -облучением.При облучении в более высоких дозах (3000 Pi применение композиции на вазелиновой основе на 23% сокращает длительность периода влажной десква- мации, и радиодерматит переходит вDesquamation caused by / j-irradiation is completely prevented. When irradiated at higher doses (3000 Pi, the use of a Vaseline-based composition reduces by 23% the duration of the period of moist desquamation, and radiodermatitis turns into
елate
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соwith
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& о& about
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более легкую форму с преобладаниемдерматита при этом ослабл етс наthe lighter form, with prevalence of dermatitis, is weakened by
сухой десквамации. При применении в50%.dry desquamation. When applied in 50%.
Claims (1)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU792830742A SU1563696A1 (en) | 1979-10-19 | 1979-10-19 | Radioprotector |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU792830742A SU1563696A1 (en) | 1979-10-19 | 1979-10-19 | Radioprotector |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU1563696A1 true SU1563696A1 (en) | 1990-05-15 |
Family
ID=20855395
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU792830742A SU1563696A1 (en) | 1979-10-19 | 1979-10-19 | Radioprotector |
Country Status (1)
| Country | Link |
|---|---|
| SU (1) | SU1563696A1 (en) |
-
1979
- 1979-10-19 SU SU792830742A patent/SU1563696A1/en active
Non-Patent Citations (1)
| Title |
|---|
| Вестник дерматологии, М., Мед., 1968, № 3, 11. Авторское свидетельство СССР № 546335. кл. А 23 К 1/16, 1971. * |
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