SU1531431A1 - 1-(isoflavonyl-7-oxycarbonylvinyl)-4- (isoflavonyl-7-oxycarbonylmethylenoxy) benzene having hypotensive and hypolipidemic activities
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1-(isoflavonyl-7-oxycarbonylvinyl)-4- (isoflavonyl-7-oxycarbonylmethylenoxy) benzene having hypotensive and hypolipidemic activities
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Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
FIELD: chemistry of heterocyclic compounds which can be used in medicine. SUBSTANCE: the synthesis of the desired compound is effected by reacting 7-hydroxyisoflavone with 4-carboxymethyleneoxycinnamic acid dichloride in toluene on boiling. The yield 70%, mp 282-283 C, the empirical formula: CHO. The toxicity LDgreater than 3000 mg/kg. The hypotensive activity of the new compound is by 2 times greater than that of theobromine, and the hypolipidemic activity of the new compound is by 1.5 times greater than that of cetamiphene. EFFECT: new compounds of said class which are more active within a wide range of activities. 2 tbl
SU4447378/04A1988-05-241988-05-241-(isoflavonyl-7-oxycarbonylvinyl)-4- (isoflavonyl-7-oxycarbonylmethylenoxy) benzene having hypotensive and hypolipidemic activities
SU1531431A1
(en)
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