SU1486169A1 - Method of treating hypertension disease - Google Patents

Description

The invention relates to medicine, in particular to the treatment of diseases of the cardiovascular system, and can be used for the treatment of hypertension 1 and 2 stages.

The aim of the invention is to reduce the duration of treatment.

The method is as follows.

After 1 h after a light breakfast, saline is injected intravenously. After 10-20 minutes of the patient's stay at rest in a horizontal position, the blood pressure stabilizes at a certain level, which is fixed as the baseline. After that, angiotensin II is injected into the dropper from the calculation 1-5 ng / kg / min.

When exceeding the average blood pressure at 25 - 50 mm Hg. Art. treatment with α-adrenergic blockers, vasodilators, diuretics is indicated from the initial one.

With an increase in mean blood pressure of 10 - 24 mm Hg. Art. treatment with β-blockers in combination with inhibitors of angiotensin-1 converting enzyme is indicated.

Example. Patient B., 61, was admitted to the hospital with a diagnosis of hypertension stage 2. Treatment with clonidine was ineffective.

The patient received a test with angiotensin P. Initial blood pressure 170/110 mm Hg. Art., average blood pressure 130 mm Hg. Art. With the introduction of angiotensin in a dose of 1 ng / kg / min, an increase in mean blood pressure to 140 mm Hg was observed. Art. Based on the results of the test, the patient was prescribed therapy with captoprim at a dose of 75 mg / day. On the 2nd day after the drug treatment, the patient's state of health improved, headaches stopped, dizziness, BP decreased to 140/90 mm Hg. Art. After 10 days of admission to the clinic, the patient was discharged in a satisfactory condition.

Th

1486169

Claim

A method of treating hypertension by administering antihypertensive drugs after a functional test, characterized in that, in order to shorten the treatment time, angiotensin II is administered intravenously to a patient at the rate of 1-5 ng / kg / min and with an increase in mean arterial pressure of 25-50 mm Hg Art. spend treating1486169

α-adrenoblockers in combination with diuretics, and with an increase in blood pressure of less than 25 mm Hg. Art. to the patient

β-blockers are introduced in combination with angiotensin-1 -converting enzyme inhibitors.

Claims (1)

To reduce the duration of treatment of hypertension, angiotensin II is administered intravenously to a patient at a rate of 1–5 ng / kg / min and with an increase in mean arterial pressure of 25–50 mmHg. Art. treatment with a-adrenergic blockers in combination with diuretics, and with an increase in mean arterial pressure of less than 25 mm Hg. Art. β-blockers are administered in combination with angiotensin-1 -converting enzyme inhibitors.