SU1469826A1 - Copolymer of l-lysine and l-glutamic acid containing side groups and showing prolonged hypotensive activity and compensatory effect at hemorrhagic shock, and a method of its preparing - Google Patents

Copolymer of l-lysine and l-glutamic acid containing side groups and showing prolonged hypotensive activity and compensatory effect at hemorrhagic shock, and a method of its preparing

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Publication number
SU1469826A1
SU1469826A1 SU4091453/05A SU4091453A SU1469826A1 SU 1469826 A1 SU1469826 A1 SU 1469826A1 SU 4091453/05 A SU4091453/05 A SU 4091453/05A SU 4091453 A SU4091453 A SU 4091453A SU 1469826 A1 SU1469826 A1 SU 1469826A1
Authority
SU
USSR - Soviet Union
Prior art keywords
copolymer
lysine
glutamic acid
preparing
acid containing
Prior art date
Application number
SU4091453/05A
Other languages
Russian (ru)
Inventor
Г.П. Власов
В.А. Цырлин
В.А. Гусель
Л.Б. Надеждина
Е.Н. Андреева
Т.А. Комогорова
А.В. Сыренский
Н.С. Рубанова
Г.С. Мазуркевич
А.И. Тюкавин
И.В. Крецер
Original Assignee
Институт Высокомолекулярных Соединений Ан Ссср
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Институт Высокомолекулярных Соединений Ан Ссср filed Critical Институт Высокомолекулярных Соединений Ан Ссср
Priority to SU4091453/05A priority Critical patent/SU1469826A1/en
Application granted granted Critical
Publication of SU1469826A1 publication Critical patent/SU1469826A1/en

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  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

FIELD: organic chemistry. SUBSTANCE: invention ensures to synthesize polymeric preparation showing physiological activity. This property is provided by new substance structure of the general formula 4·10-6·10where l 0.13-20; n 0.47-0.54; k:(l+n) 0.33:0.67, molecular mass is. Method of synthesis involves treatment of 1 mas. p. copolymer of L-lysine with L-glutamic acid with 1-5 mas. p. tert. -butylhydroxycarbonyl derivative carbonate of dopamine of the formulain aqueous solution, at pH 7-8. Synthesized copolymer can be used in medicine. EFFECT: improved method of synthesis. 3 cl, 1 tbl
SU4091453/05A 1986-05-30 1986-05-30 Copolymer of l-lysine and l-glutamic acid containing side groups and showing prolonged hypotensive activity and compensatory effect at hemorrhagic shock, and a method of its preparing SU1469826A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SU4091453/05A SU1469826A1 (en) 1986-05-30 1986-05-30 Copolymer of l-lysine and l-glutamic acid containing side groups and showing prolonged hypotensive activity and compensatory effect at hemorrhagic shock, and a method of its preparing

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SU4091453/05A SU1469826A1 (en) 1986-05-30 1986-05-30 Copolymer of l-lysine and l-glutamic acid containing side groups and showing prolonged hypotensive activity and compensatory effect at hemorrhagic shock, and a method of its preparing

Publications (1)

Publication Number Publication Date
SU1469826A1 true SU1469826A1 (en) 1995-11-20

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ID=60534574

Family Applications (1)

Application Number Title Priority Date Filing Date
SU4091453/05A SU1469826A1 (en) 1986-05-30 1986-05-30 Copolymer of l-lysine and l-glutamic acid containing side groups and showing prolonged hypotensive activity and compensatory effect at hemorrhagic shock, and a method of its preparing

Country Status (1)

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SU (1) SU1469826A1 (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6939539B2 (en) 1994-05-24 2005-09-06 Yeda Research & Development Copolymer-1 improvements in compositions of copolymers
US7163802B2 (en) 1998-09-25 2007-01-16 Yeda Research And Development Co., Ltd. Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
US7279172B2 (en) 1998-07-23 2007-10-09 Yeda Research And Development Co., Ltd. Treatment of autoimmune conditions with copolymer 1 and related copolymers
US7425332B2 (en) 1998-07-23 2008-09-16 Yeda Research And Development Co., Ltd. Treatment of autoimmune conditions with Copolymer 1 and related Copolymers
US7429374B2 (en) 2001-12-04 2008-09-30 Teva Pharmaceutical Industries, Ltd. Process for the measurement of the potency of glatiramer acetate
US7495072B2 (en) 2004-09-09 2009-02-24 Teva Pharmaceutical Industries, Ltd. Process for preparation of mixtures of polypeptides using purified hydrobromic acid
US7560100B2 (en) 2004-09-09 2009-07-14 Yeda Research And Development Co., Ltd. Mixtures of polypeptides, compositions containing and processes for preparing same, for treating neurodegenerative diseases
US10301413B2 (en) * 2006-08-07 2019-05-28 University Of Washington Mixed charge copolymers and hydrogels

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7625861B2 (en) 1994-05-24 2009-12-01 Yeda Research And Development Co., Ltd. Copolymer-1 improvements in compositions of copolymers
US8367605B2 (en) 1994-05-24 2013-02-05 Yeda Research And Development Co. Ltd. Copolymer-1 improvements in compositions of copolymers
US7199098B2 (en) 1994-05-24 2007-04-03 Yeda Research And Development Co., Ltd. Copolymer-1 improvements in compositions of copolymers
US6939539B2 (en) 1994-05-24 2005-09-06 Yeda Research & Development Copolymer-1 improvements in compositions of copolymers
US7279172B2 (en) 1998-07-23 2007-10-09 Yeda Research And Development Co., Ltd. Treatment of autoimmune conditions with copolymer 1 and related copolymers
US7425332B2 (en) 1998-07-23 2008-09-16 Yeda Research And Development Co., Ltd. Treatment of autoimmune conditions with Copolymer 1 and related Copolymers
US7615359B2 (en) 1998-09-25 2009-11-10 Yeda Research And Development Co., Ltd. Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
US7163802B2 (en) 1998-09-25 2007-01-16 Yeda Research And Development Co., Ltd. Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
US8399211B2 (en) 1998-09-25 2013-03-19 Yeda Research And Development Co., Ltd. Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
US7429374B2 (en) 2001-12-04 2008-09-30 Teva Pharmaceutical Industries, Ltd. Process for the measurement of the potency of glatiramer acetate
US7923215B2 (en) 2001-12-04 2011-04-12 Teva Pharmaceutical Industries, Ltd. Process for the measurement of the potency of glatiramer acetate
US7495072B2 (en) 2004-09-09 2009-02-24 Teva Pharmaceutical Industries, Ltd. Process for preparation of mixtures of polypeptides using purified hydrobromic acid
US7560100B2 (en) 2004-09-09 2009-07-14 Yeda Research And Development Co., Ltd. Mixtures of polypeptides, compositions containing and processes for preparing same, for treating neurodegenerative diseases
US10301413B2 (en) * 2006-08-07 2019-05-28 University Of Washington Mixed charge copolymers and hydrogels

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