SU1454396A1 - Method of external aortal contrpulsation - Google Patents

Abstract

The invention of medicine for medicine, particularly cardiology. The goal is to enhance the coronary blood flow during long-term external aortic counterpulsation by increasing the force of automyscular contraction and preventing its fatigue, creating an auxiliary biological pump from non-vital skeletal automuscles with their subsequent electrical stimulation. For this purpose skeletal denervating an out ysh- zu allocated for arterio-venous leg, and shift it to the left pleural cavity or freely transplanted into the left pleural cavity skeletal automyshtsu isolated from femur arterio-venous anastomosis with the last leg of a container placed in the chest cavities, followed by the introduction of automyscula perpendicular into muscle, muscle fibers across the entire width of automyscus electrodes, the wrapping of the proximal part of the descending thoracic aorta and the implementation of mutations with square-shaped bipolar pulses with a duration of 0.1-0.5 ms, a frequency of 50-100 Hz, an amplitude of 2-8 V using an electrostimulator, and the stimulation is carried out not every diastole but with frequency stimulating automyscula packs, in the range of 20-25 per minute. SS (L

Description

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The invention relates to medicine, namely cardiology.

The purpose of the invention is to enhance the coronary blood flow during prolonged external aortic counterpulsation by increasing the force of contraction of automyscules and preventing its fatigue.

The goal is achieved by the fact that the method proposes the use of a biological pump from skeletal automyscle with their subsequent electrical stimulation.

The method is carried out as follows.

On mongrel dogs, skeletal muscle is isolated on the arterio-venous pedicle, and the proximal section of the descend is wrapped around it. the thoracic aorta, then autologous muscles perpendicular to the muscle fibers are introduced into the thickness of the automagna.

electrodes and stimulation with bipolar pulses of rectangular shape with a duration of 0.1-0.5 ms, frequency 50-100 Hz, amplitude 2-8 V with an electrostimulator, and stimulation is carried out first through 2-8 cardiac cycles , and as automake is trained in each diastole.

With an individual selection of stimulation parameters, a twofold reduction of the final diastolic pressure is achieved, as compared with the prototype.

The invention is illustrated as follows.

An example is a dog weighing 21 kg. Anesthesia - intravenous 5% barbamil 12 ml. For the creation of a biological pump, the adductor longus dextra, which is isolated on the arterio-venous pedicle, was selected. Torakoto 4 SL

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min left in IY intercostal space. The diameter of the proximal thoracic aorta, which was 12 mm, was measured with a special clamp. A calibration tube with a diameter of 3 mm larger than the diameter of the aorta was picked up and wrapped around the automyscleus taking into account the transverse ra (;; the position of the muscle fibers. Excess muscles were cut off. The peromuscular muscles of the peripheral | muscular muscle fibers were inserted (supplied with electrocardiostimuli). torus EKS-2). The electrodes were connected to an external muscle stimulator. A test was performed for 2 hours with asynchronous stimulation of the muscle with a frequency of 60 sofas per minute. The pulse duration was 0.5 ms, the pulse frequency was 60 Hz, the length packet body 200 ms, ES threshold 0.4 B, and the maximum contractions were reached at 3.5 M. After the training, the automysh was transplanted into the chest cavity, with the help of vasocontaining apparatus, the femoral vein and arteries were anastomosed with the subclavian vein and artery. The aorta is wrapped in a transplanted automysus. the left ventricular lug is hemmed by the myocardial electrode. The electrodes from the heart and the automuscles are connected to the external muscle stimulator and the control stimulation of the muscle is performed in a biocontrol for 2 hours. On the arterial pressure curve, tion biological pump creates during dia |: toly additional pressure rise, PRE1 ytayushy 4 mmHg. Art. systolic; BP, and reduces the final diastolic pressure by 8 mm Hg. Art. This data

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indicate the effectiveness of aortic counterpulsation. The external device is replaced by an implantable stimulator.

The dog is clogged for 8 days. When viewed narrowing of the lumen of the aorta is not detected. Macroscopic and histological data confirmed the viability of automyscula. The stimulating system works fine.

Thus, in comparison with the prototype, the proposed method allows for effective long-term aortic counterpulsation using a biological pump. The method can be applied in the clinic to patients suffering from chronic heart failure caused by cardiomyopathy, suffering from extensive myocardial infarction, IHD patients, who are contraindicated for aorto-coronary bypass surgery.

Claims (1)

Invention Formula The method of external aortic counterpulsation by wrapping the aorta with an autograft followed by its electrocution, characterized in that, in order to enhance the blood flow during a long counterpulsation, skeletal muscles are used as autograft, and their electrical stimulation is carried out with a bundle of pulses lasting 0.1- 0.5 ms, frequency 30 50-100 Hz, amplitude 2-8 V, and electrostimulation is carried out first through 2-8 cardiocycles, and as far as fitness is done, the autos in each diastole indicate the effectiveness of aortic counterpulsation. The external device is replaced by an implantable stimulator. The dog is clogged for 8 days. When viewed narrowing the lumen of the aorta is not detected. Macroscopic and histological data confirmed the viability of automyscula. The stimulating system works fine. Thus, in comparison with the prototype, the proposed method allows for effective long-term aortic counterpulsation using a biological pump. The method can be applied in the clinic to patients suffering from chronic heart failure caused by cardiomyopathy, suffering from extensive myocardial infarction, IHD patients, who are contraindicated for aorto-coronary bypass surgery. Invention Formula