SU1446526A1 - Method of determining the degree of destruction in acute appendicitis cases - Google Patents

Method of determining the degree of destruction in acute appendicitis cases Download PDF

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Publication number
SU1446526A1
SU1446526A1 SU864081515A SU4081515A SU1446526A1 SU 1446526 A1 SU1446526 A1 SU 1446526A1 SU 864081515 A SU864081515 A SU 864081515A SU 4081515 A SU4081515 A SU 4081515A SU 1446526 A1 SU1446526 A1 SU 1446526A1
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SU
USSR - Soviet Union
Prior art keywords
acute appendicitis
degree
alkaline phosphatase
peroxidase
destruction
Prior art date
Application number
SU864081515A
Other languages
Russian (ru)
Inventor
Степан Митрофанович Луценко
Сергей Дмитриевич Шаповал
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Запорожский медицинский институт
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Priority to SU864081515A priority Critical patent/SU1446526A1/en
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Publication of SU1446526A1 publication Critical patent/SU1446526A1/en

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Abstract

Изобретение относитс  к медицине и касаетс  способа диагностики декструктивных форм острого аппендицита . Цель изобретени  - повьппение точности диагностики острого аппендицита и определение степени деструктивного процесса. Дл  этого определ ют щелочную фосфатазу и пероксида- зу в нейтрофилах периферической крови с вычислением среднего цитохимического коэффициента и по отклонению от нормы щелочной фосфатазы и перо- ксидазы до 191-209% и 17-19% соответственно суд т о наличии гангренозной формы воспалени , а до 268-282% и 30-32% - о гангренозно-перфоративной форме.This invention relates to medicine and concerns a method for diagnosing destructive forms of acute appendicitis. The purpose of the invention is to improve the accuracy of diagnosis of acute appendicitis and determine the degree of the destructive process. To do this, alkaline phosphatase and peroxidase in peripheral blood neutrophils are determined by calculating the average cytochemical coefficient and, by abnormal alkaline phosphatase and peroxidase, up to 191–209% and 17–19%, respectively, the presence of a gangrenous form of inflammation, and up to 268-282% and 30-32% - about the gangrenous-perforative form.

Description

Изобретение относитс  к медицине И касаетс  способов диагностики де-г структивных форм острого аппендицитаThe invention relates to medicine and concerns methods for the diagnosis of de-g structural forms of acute appendicitis.

Цепью изобретени   вл етс  повышение точности способа.The chain of the invention is to improve the accuracy of the method.

Способ осуществл ют следующим образом.The method is carried out as follows.

Исследуют щелочную фосфатазу (ЩФ) и пероксидазу (ПО) по известным мето дам в лейкоцитах с вычислением среднего цитохимического коэффициента по известной формуле. По отклонению от нормы щелочной фосфатаэы до 191- 209%, пероксидазы до 17-19% суд т о наличии флегмозной формы, а по гиперферментации щелочной фосфата- зы до 268-282%, пероксидазы до 30- 32% - о гангренозной форме острого аппендицита. Щелочна  фосфатаза .вы вл етс  в цитоплазме в виде черного или темно-серого окрашивайи , пероксидаза - в виде коричневых гранул .Alkaline phosphatase (alkaline phosphatase) and peroxidase (PO) are investigated by known methods in leukocytes with calculation of the average cytochemical coefficient using the well-known formula. By abnormal alkaline phosphate up to 191-209%, peroxidase up to 17-19%, the presence of a phlegm form is judged, and by hyperfermentation alkaline phosphatase up to 268-282%, peroxidase up to 30-32% - about an acute appendicitis gangrenous form . Alkaline phosphatase. You are in the cytoplasm in the form of a black or dark gray color, peroxidase - in the form of brown granules.

Исследование активности ЩФ и ПО позвол ет с высокой степенью достоверности судить о наличии деструкции именно в червеобразном отростке, если активность ЩФ не ниже 191% и не вьпае 282% по отношению к норме, а ПО не ниже 17% и не вьппе 32% по отклонению от нормы,,The study of alkaline phosphatase and software activity allows a high degree of reliability to judge the presence of destruction in the vermiform process, if the alkaline phosphatase activity is not lower than 191% and not higher than 282% in relation to the norm, and software is not lower than 17% and not 32% by deviation from the norm ,,

Claims (1)

Формула изобретени Invention Formula Способ определени  степени деструкции при остром аппендиците путем исследовани  лейкоцитов крови, о т- личающийс  тем, что, с целью повышени  точности способа, определ ют содержание щелочной фосфата- зы и пероксидазы в лейкоцитах и при повышении активности щелочной фосфатазы и пероксидазы от нормы на 191-209% и 17-19% суд т о наличии флегмонозной формы, до 268-282% и 30-32% - о гангренозной форме.The method for determining the degree of destruction in acute appendicitis by examining blood leukocytes, is characterized in that, in order to increase the accuracy of the method, the content of alkaline phosphatase and peroxidase in leukocytes is determined and with increasing activity of alkaline phosphatase and peroxidase from the norm 209% and 17-19% are judged on the presence of phlegmonous form, up to 268-282% and 30-32% - of the gangrenous form.
SU864081515A 1986-06-27 1986-06-27 Method of determining the degree of destruction in acute appendicitis cases SU1446526A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SU864081515A SU1446526A1 (en) 1986-06-27 1986-06-27 Method of determining the degree of destruction in acute appendicitis cases

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SU864081515A SU1446526A1 (en) 1986-06-27 1986-06-27 Method of determining the degree of destruction in acute appendicitis cases

Publications (1)

Publication Number Publication Date
SU1446526A1 true SU1446526A1 (en) 1988-12-23

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SU864081515A SU1446526A1 (en) 1986-06-27 1986-06-27 Method of determining the degree of destruction in acute appendicitis cases

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3209804A4 (en) * 2014-10-22 2018-02-28 The George Washington University A Congretionally Chartered Not-For-Profit Corp. Blood biomarkers for appendicitis and diagnostics methods using biomarkers
US11629383B2 (en) 2015-01-12 2023-04-18 The George Washington University a Congressionally Chartered Not-for-Profit Corporation Blood biomarkers for respiratory infections

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Мат шин И.М, О пользе единой доктрины в неотложной хирургии. - Клиническа хирурги , 1978, № 4, с.1-9. *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3209804A4 (en) * 2014-10-22 2018-02-28 The George Washington University A Congretionally Chartered Not-For-Profit Corp. Blood biomarkers for appendicitis and diagnostics methods using biomarkers
US11066706B2 (en) 2014-10-22 2021-07-20 The George Washington University, A Congressionally Chartered Not-For-Profit Corporation Blood biomarkers for appendicitis and diagnostics methods using biomarkers
US11371096B2 (en) 2014-10-22 2022-06-28 The George Washington University a Congressionally Chartered Not-for-Profit Corporation Blood biomarkers for appendicitis and diagnostics methods using biomarkers
US11629383B2 (en) 2015-01-12 2023-04-18 The George Washington University a Congressionally Chartered Not-for-Profit Corporation Blood biomarkers for respiratory infections

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