SU1395328A1 - Method of treatment of diffusion neurodermite - Google Patents

Abstract

The invention relates to medicine, more specifically to dermatology, intended for hospitals and dispensaries. The purpose of the invention is to reduce the time of treatment due to the use of the 1% solution of Vilozen as an immunomodulatory agent. For this, to 25 mg of the dry preparation "Vilosen, 2.5 ml of distilled water is added and the resulting solution is instilled with 3 drops in each nostril every 2 hours.

Description

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The invention relates to medicine, EB in particular to dermatology, and can be used in hospitals and outpatient departments.

The purpose of the invention is to reduce the duration of treatment and prevent complications by using the solution of Vilozen. I% -HOFO as an immunomodulating agent.

A method for treating patients with diffuse neurodermatitis is carried out as follows.

 The course of treatment is 14 days, and after a week, the course is repeated. To 25 mg of dry fipenapaTa, Vilosen is added 2.5 ml of distilled water and the resulting plant is instilled with 3 drops in each nostril every 2 hours with an overnight break. The next sample is dissolved noc; i.e., the previous one is used. ; Example 1. The patient turned to a dermatologist about a painful diffuse skin lesion, irritability,. insomnia The disease began at the age of three, when rashes appeared on the knees and elbows. It was treated on an outpatient basis. Exacerbation usually in spring. Remissions are long, usually in pestilence. Were treated with antihistamines (ipeYiapaTaMH (diazolin, diphenhydramine, supras-), vitamins (B |, ascorutin), sedative- (ibiMH (valerian tincture, motherwort), | orticosteroid, ointments (flucinar, fluorocort), received quartz. none. Recently, the process has often been complicated by pyoderma Objectively: the pathological skin process is localized on the skin of the face, conch, hands, elbow and knee folds, foci Irregular outlines. and small scale scales E gray oily blood crusts. a plurality of linear excoriations and cracks. The face foci are located around the mouth, eyes, and nososchechnyh in nasolabial folds. nails i.meyut polished appearance.

Diagnosis: diffuse atopic dermatitis. From February 26 to June 3, 1980, the patient was examined and underwent treatment at the department of dermatovenerology of the Kiev Institute for the improvement of doctors.

On April 8, 1980, the number of B-lymphocytes was 21%, T-lymphocytes - 37%. The treatment was carried out according to the following scheme.

1.2 of the course “Vilozen, 3 drops in each nostril every 2 hours with a night break. The break between courses was 2 weeks.

2. Smfayuschiy cream.

The patient was bothered by painful paroxysmal itching, aggravated in the evening, leading to a decrease in working capacity, depression, and increased comfort. Reducing itching is sick

Tyla after 1 day of treatment. By the end of the first course, the itching had completely stopped, sleep was normalized. After the second course, elasticity was restored, hyperemia, infiltration resolved. No adverse effects or complications were observed.

In the control study on 24 May 1980: B cells, T cells - 41%. Remissi lasted 6 months.

Example 2. The patient turned to a dermatologist about the painful itching, diffuse skin lesion, irritability, insomnia. The disease began 3 years ago, when rashes appeared on the knee and elbow bends. It was treated on an outpatient basis with antihistamine preparations, sedatives, corticosteroid ointments. Recently, the process has been complicated by pyoderma.

Objectively: the pathological skin process is localized on the skin of the face, neck, hands, elbows and knees. The skin in the foci is hyperemic: infiltrated, lichened, covered with scaly and small plastic scales of black color, with bloody crusts. There are many linear excoriations. Nails 5 have a polished look.

From April 6 to June 1, the patient was examined and underwent treatment at the Department of Dermatology and Venereology of the Kiev Institute for the Advancement of Doctors. Before treatment, the number of B-lymphocytes was 23%, 0 T-lymphocytes - 44%.

The treatment was carried out according to the following scheme: 2 courses “Vilozen, 3 drops in each nostril every 2 hours with a night break. The break between courses was 2 weeks.

The patient was bothered by a painful primordial zoo.d, aggravated at night, leading to a decrease in performance, sleep disturbance. The reduction in itching was noted for 5 days of treatment. By the end of the first course, the itching had completely stopped, sleep had normalized. After the second course, the skin was cleansed, elasticity was restored, resolved by hyperemia, infiltration. Side effects and complications were not observed.

5 In the study after the 1st course: B-lymphocytes - 24%, T-lymphocytes - 58% after the 2nd; second course: B-lymphocytes - 19%, T-lymphocytes - 65%. Remissi lasts 2 months.

Claims (1)

Formula of invention A method for treating diffuse neurodermatitis by administering a drug with an immunomodulatory effect, characterized in that, in order to shorten the treatment time and prevent complications, a patient is given a 1% solution of Vilosen intranasally 8 times a day with a break for the night for 12-16 days 0