SU1342500A1 - Method of treatment of glaucoma - Google Patents

Abstract

This invention relates to ophthalmology. The purpose of the invention is to simplify the method and reduce the trauma. The agar ring is placed in the projection of the drainage system, and an annular active electrode is supplied from above. The current strength with the introduction of papain 0,2-0,4 mA. The thickness of the active electrode is selected so that the current density is no more than 0.057 mA / mm. The position of the drainage zone is determined with the help of a diaphanoscope.

Description

This invention relates to medicine, in particular to ophthalmology.

The purpose of the invention is to simplify the method and reduce its trauma due to the fact that medicinal substances are introduced into the drainage zone by electrophoresis of annular agar casts, the diameter of which corresponds to the diameter of the drainage zone corresponding to the diameter

active and active electrode electrode

The method is carried out as follows.

After epibulbar instillation anesthesia with 0.25% dikain on ILUIT with a micrometric scale, when illuminated with a diaphanoscope through the para-optical zone of the cornea, the position of the drainage zone is determined in linear units. Illumination is conducted, the front border of the ciliary body is determined, which is seen by the black ring Hk against the background of the pink glow of the limbus. The sharpness of the image is brought to the front surface of the lens. The horizontal diameter of the black ring in millimeters is measured, which corresponds (in comparison with the gonioscopic data) to the position of the drainage zone. The resulting diameter in millimeters serves as a criterion for selecting the diameter of the active ring electrode and the ring agar impression. Papa in is introduced into the liquid cooling agar at the rate of 0.02% or dionin at the rate of 2% and poured into special forms. The resulting annular blindly 5% agar has a height and width of 2 mm, the skewness of the inner surface 30 °, which corresponds to the curvature of the eye block in the limbus. The agar ring is placed in the projection of the drainage system, an annular active electrode is supplied from above. The current strength when introducing papain is 0.2-0.4 mA. Session time with the introduction of papain 4 min. The thickness of the active electrode is chosen so that the current density is no more than

2

0.057 mA / mm since a high current density causes a conjunctival burn.

Example. Patient S., 58 years old, was admitted about the open primary with moderately elevated IOP with the maximal miotics regime for glaucoma of the left eye. Before surgery:

27.76,, 12,, 09,.

0

0

Q

Surgical treatment was not carried out. After three sessions of local electrophoresis of papain, in the area of the eye drainage system with a current of 0.2 mA and a session duration of 2 minutes, the otfatomotonus was compensated - P, 15.88 ,. , 21, 23,.

PRI mme R 2. Patient M., 68 years old, was enrolled for an open-angle developed IOP with high IOP in glaucoma of the left eye.

Conducted 5 sessions of local 5 electrophoresis of papain in the area of the eye drainage system with a current of 0.4 mA, the duration of the session 4 min. Surgical treatment was postponed due to the complete compensation of the ophthalmic motility with double instillation of pilocarpine.

Before treatment:, 4,, 08, Becker's coefficient (CB) 417.

After electrophoresis: P (25.47, 25, 16,.

After electrophoresis and double instillation of pilocarpine:, 3 | ,nineteen, .

PRI me R 3. Patient U., 62 years. Diagnosis: open-angle, early with high IOP, with maximal miotics, glaucoma of the right eye.

3 sessions of local electrophoresis of papain were conducted on the area of the drainage system from gel impressions with a current of 0.3 mA for 3 minutes.

Before treatment:, 11,, 13,.

After electrophoresis:, 70,, 22, -.

Q

Claims (1)

Invention Formula ° A method for treating glaucoma by topical administration of a medicinal protein. 50 the drainage area of the eye, characterized in that, in order to simplify the method and reduce its trauma, local papain electrophoresis with a current of 0.2-0.4 mA, current density of up to 0577 mA / mm from a 5% impression is carried out agar in the form of a ring with an annular electrolyte, the diameters of the impression and the electrode being equal to the diameter of the ring in the drainage zone of the eye.