SU1337096A1 - Method of treatment of septic diseases - Google Patents

Abstract

To prevent depression of the immune system, lysozyme is administered. a dose of 1 mg / kg of body weight, an antibiotic and a protease inhibitor in average therapeutic doses for 30-40 ml of a 0.5% novocaine solution. 00 with O5

Description

The invention relates to medicine and can be used for the treatment of purulent-septic diseases.

The aim of the invention is to reduce the duration of treatment and the number of complications by preventing depression of the immune system.

Example 1. Patient B., 28 years old, received for furunculosis complicated by sepsis. Produced an autopsy ulcers. Oxadillin and dimethyl sulfoxide, protein preparations were injected intravenously. The patient's condition did not improve. Purulent foci appeared in various parts of the body. Their opening and massive antibiotic therapist did not produce any effect. The patient on the rear foot was treated with a lymphatic vessel into which a catheter was inserted. The sensitivity of the causative agent to cephalosporin antibitics was assessed; in a 1.1 phatic vessel, 4 g of klaforain was introduced once every two days in 30 ml of a 0.5% solution of novocaine in combination with 20 thousand units. contrikala and 50 mg of lysozyme. The rate of drug administration was 2 ml / min. Total held 7 injections. A clear improvement in the patient's condition was noted already after the second administration of drugs: the temperature decreased, the separation of purulent contents from wounds decreased. Hemogram normalization and blood sterilization were observed. Vyssan home after 34 days from the start of treatment. Long-term results, good, there was no relapse.

Example 2. Patient C, 52 le, was admitted for treatment for acute right - sided pneumonia, which complicated the postoperative period after commissomia and protector. Yu. Yemtsov editor N. Gorvat Tekhred L. Serdyukova Corrector A.T.

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valve tirage. From the blood of a high staphylococcus aureus. Treatment with intramuscular administration of amikacin and intravenous infusion of tseporin, anti-staphylococcal plasma, protein preparations, and whole blood did not produce an effect. After 3 days, endolymphatic infusions of cephalisin were prescribed in 5 g each with 30 thousand units. kontrikala and 100 m of lysozyme in 50 ml of 0., 5% aqueous solution of novocaine. The rate of introduction of 3 ml / m. The preparations were administered once every two days with a course of 7 infusions. A positive effect was noted after 4 days. The general condition of the patient improved, the temperature decreased; in parallel, the size of the pneumonic focus on the radiograph was also reduced. Blood sterilization occurred after 3 infusions. 30 days after the start of treatment, the patient is sent to a sanatorium for rehabilitation treatment. When examined after six months, the state is satisfactory, there was no recurrence.

The proposed method of treatment allows to reduce the duration of treatment from 3-4 months in the prototype method to 20-45 days in the absence of complications and relapses.

Claims (1)

Invention Formula A method for treating septic diseases by endolymphatic administration of medicinal substances, which is mainly due to the fact that, in order to prevent depression of the immune system, it is administered t-lysozyme at a dose of 1 mg / kg of body mass, an antibiotic and a protease inhibitor in average therapeutic doses of 30-40 ml of a 0.5% solution of novocaine.