SU1273977A1 - Method of modelling sepsis - Google Patents
Method of modelling sepsis Download PDFInfo
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- SU1273977A1 SU1273977A1 SU843792558A SU3792558A SU1273977A1 SU 1273977 A1 SU1273977 A1 SU 1273977A1 SU 843792558 A SU843792558 A SU 843792558A SU 3792558 A SU3792558 A SU 3792558A SU 1273977 A1 SU1273977 A1 SU 1273977A1
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- SU
- USSR - Soviet Union
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- sepsis
- suspension
- development
- foci
- culture
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Abstract
Изобретение относитс к медицине , в частности к хирургии, может быть применено в клиниках и лаборатори х в профилактике, ранней диагностике и лечении заболевани сепсисом. Цель изобретени - создание модели сепсиса с про влением метастатических очагов во внутренних органах. Дл этого культуру стафилококка выращивали при 37°С на м со-пептонном агаре. Содержание микробов во взвеси определ ют по оптическому стандарту мутности, что составл ет 10 - 10 микробных тел в 1 мл. Крысам массой 120-350 г внутримьшечно однократно .ввод т в зависимости от массы 0,15 0 ,3 мл взвеси суточной культуры стафилококка в 10%-ном растворе CaCl. Предлагаемый способ вызывает развитие местного гнойного очага, бактериемию , вторичные пиемические очаги и дистрофические изменени во внуто SS ренних органах, сопровождающиес летальностью , т.е. вызывают развитие комплекса критериев, характеризующих заболевание сепсисом у человека.The invention relates to medicine, in particular to surgery, can be applied in clinics and laboratories in the prevention, early diagnosis and treatment of sepsis. The purpose of the invention is to create a model of sepsis with the appearance of metastatic foci in the internal organs. For this, staphylococcal culture was grown at 37 ° C on m-peptone agar. The microbial content of the suspension is determined by the optical turbidity standard, which is 10 to 10 microbial cells per ml. Rats weighing 120-350 g were intramuscularly injected once depending on the weight of 0.15-0.3 ml suspension of the daily culture of staphylococcus in 10% CaCl solution. The proposed method causes the development of a local suppurative focus, bacteremia, secondary pyemichesky foci and dystrophic changes in the SS of the renal organs accompanied by mortality, i.e. cause the development of a set of criteria that characterize the disease sepsis in humans.
Description
ГОGO
N|N |
СОWITH
соwith
vlvl
«-4"-four
Claims (1)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SU843792558A SU1273977A1 (en) | 1984-07-23 | 1984-07-23 | Method of modelling sepsis |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SU843792558A SU1273977A1 (en) | 1984-07-23 | 1984-07-23 | Method of modelling sepsis |
Publications (1)
Publication Number | Publication Date |
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SU1273977A1 true SU1273977A1 (en) | 1986-11-30 |
Family
ID=21139209
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SU843792558A SU1273977A1 (en) | 1984-07-23 | 1984-07-23 | Method of modelling sepsis |
Country Status (1)
Country | Link |
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SU (1) | SU1273977A1 (en) |
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1984
- 1984-07-23 SU SU843792558A patent/SU1273977A1/en active
Non-Patent Citations (1)
Title |
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Hermeck A.S. е.а. Archive surgery, 1969, 197, p.1973. * |
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