SU1273370A1 - Method of modelling bronchospasm - Google Patents

Method of modelling bronchospasm Download PDF

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Publication number
SU1273370A1
SU1273370A1 SU853876350A SU3876350A SU1273370A1 SU 1273370 A1 SU1273370 A1 SU 1273370A1 SU 853876350 A SU853876350 A SU 853876350A SU 3876350 A SU3876350 A SU 3876350A SU 1273370 A1 SU1273370 A1 SU 1273370A1
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SU
USSR - Soviet Union
Prior art keywords
bronchospasm
animal
scolopendra
modelling
activation
Prior art date
Application number
SU853876350A
Other languages
Russian (ru)
Inventor
Борис Николаевич Орлов
Василий Николаевич Крылов
Леонид Владимирович Ошевенский
Надежда Вениаминовна Корнева
Original Assignee
Научно-исследовательский институт химии при Горьковском государственном университете им.Н.И.Лобачевского
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Application filed by Научно-исследовательский институт химии при Горьковском государственном университете им.Н.И.Лобачевского filed Critical Научно-исследовательский институт химии при Горьковском государственном университете им.Н.И.Лобачевского
Priority to SU853876350A priority Critical patent/SU1273370A1/en
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Publication of SU1273370A1 publication Critical patent/SU1273370A1/en

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Abstract

Изобретение относитс  к экспериментальной медицине. Цель изобрете- ни  - создание модели бронхоспазма с активацией нейрогуморальных механизмов . Наркотизируют и обездвиживают животное. В трахею животного вставл ют катетер, который соединен с аппаратом искусственного дыхани  и с датчиком давлени . При этом на самописце регистрируют параметры, физиологических функций и давление в системе аппарат - легкие. Бронхоспазм вызьшают внутривенным введением 0,01§ 0,1 мг/кг  да сколопендры кольчатой. Величина и длительность бронхоспазма (Л зависит от вводимой дозы  да.This invention relates to experimental medicine. The purpose of the invention is to create a model of bronchospasm with activation of neurohumoral mechanisms. Anesthetize and immobilize the animal. A catheter is inserted into the animal's trachea, which is connected to a respirator and a pressure transducer. At the same time, parameters, physiological functions and pressure in the apparatus system — lungs — are recorded on the recorder. Bronchospasm is induced by intravenous administration of 0.01 ± 0.1 mg / kg and scolopendra ringed. The magnitude and duration of bronchospasm (L depends on the dose administered yes.

Description

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Claims (1)

Формула изобретенияClaim Способ моделирования бронхоспазма путем введения биологически активных веществ, отличающийся тем, что, с целью создания модели бронхоспазма с активацией нейрогуморальных механизмов, в качестве биологически активного вещества вводят яд сколопендры кольчатой (Scolopendra cingu-: lata) в дозе 0,01-0,1 мг/кг.A method for simulating bronchospasm by introducing biologically active substances, characterized in that, in order to create a model of bronchospasm with activation of neurohumoral mechanisms, scolopendra venom (Scolopendra cingu- : lata) at a dose of 0.01-0.1 mg is administered as a biologically active substance / kg
SU853876350A 1985-03-28 1985-03-28 Method of modelling bronchospasm SU1273370A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SU853876350A SU1273370A1 (en) 1985-03-28 1985-03-28 Method of modelling bronchospasm

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SU853876350A SU1273370A1 (en) 1985-03-28 1985-03-28 Method of modelling bronchospasm

Publications (1)

Publication Number Publication Date
SU1273370A1 true SU1273370A1 (en) 1986-11-30

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Family Applications (1)

Application Number Title Priority Date Filing Date
SU853876350A SU1273370A1 (en) 1985-03-28 1985-03-28 Method of modelling bronchospasm

Country Status (1)

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SU (1) SU1273370A1 (en)

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Павленко С.М. Практикум по патофизиологии. - И.: Медицина, 1974, с.168-169. *

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