SU1218526A1 - METHOD FOR OBTAINING MELIOIDAL PRECIPITATING SERA - Google Patents

METHOD FOR OBTAINING MELIOIDAL PRECIPITATING SERA

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Publication number
SU1218526A1
SU1218526A1 SU3593628/14A SU3593628A SU1218526A1 SU 1218526 A1 SU1218526 A1 SU 1218526A1 SU 3593628/14 A SU3593628/14 A SU 3593628/14A SU 3593628 A SU3593628 A SU 3593628A SU 1218526 A1 SU1218526 A1 SU 1218526A1
Authority
SU
USSR - Soviet Union
Prior art keywords
obtaining
precipitating
melioidal
sera
melioidosis
Prior art date
Application number
SU3593628/14A
Other languages
Russian (ru)
Inventor
Н.Н. Пивень
В.И. Илюхин
Л.Д. Поповцева
Original Assignee
Волгоградский научно-исследовательский противочумный институт
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Application filed by Волгоградский научно-исследовательский противочумный институт filed Critical Волгоградский научно-исследовательский противочумный институт
Priority to SU3593628/14A priority Critical patent/SU1218526A1/en
Application granted granted Critical
Publication of SU1218526A1 publication Critical patent/SU1218526A1/en

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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Способ получения мелиоидозной преципитирующей сыворотки для идентификации возбудителя мелиоидоза путем иммунизации кроликов специфическим антигеном с адъювантом, повторной через 21 день внутривенной иммунизацией с последующим кровопусканием и выделением целевого продукта, отличающийся тем, что, с целью упрощения идентификации за счет унификации сыворотки, в качестве специфического антигена используют гретые клетки штамма Pseudomonas pseudomallei 100, подкожную иммунизацию проводят введением в две точки суспензии в дозе по 6 • 10м.к., повторную иммунизацию проводят в дозах 1 • 10, 2 • 10, 4 • 10, 8 • 10, 1,6 • 10с интервалом между инъекциями 7 дней.The method of obtaining melioidosis precipitating serum to identify the causative agent of melioidosis by immunizing rabbits with a specific antigen with an adjuvant, repeated intravenous immunization 21 days later with subsequent bleeding and release of the target product, characterized in that the heated cells of the Pseudomonas pseudomallei 100 strain, subcutaneous immunization is carried out by administering at two points of the suspension in a dose of 6 • 10mc, repeated unizatsiyu carried out at doses of 1 • 10 • 2 10 • 4 10 • 10 8, 1.6 • 10c interval between injections 7 days.

SU3593628/14A 1983-05-18 1983-05-18 METHOD FOR OBTAINING MELIOIDAL PRECIPITATING SERA SU1218526A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SU3593628/14A SU1218526A1 (en) 1983-05-18 1983-05-18 METHOD FOR OBTAINING MELIOIDAL PRECIPITATING SERA

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SU3593628/14A SU1218526A1 (en) 1983-05-18 1983-05-18 METHOD FOR OBTAINING MELIOIDAL PRECIPITATING SERA

Publications (1)

Publication Number Publication Date
SU1218526A1 true SU1218526A1 (en) 1999-04-10

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ID=60539539

Family Applications (1)

Application Number Title Priority Date Filing Date
SU3593628/14A SU1218526A1 (en) 1983-05-18 1983-05-18 METHOD FOR OBTAINING MELIOIDAL PRECIPITATING SERA

Country Status (1)

Country Link
SU (1) SU1218526A1 (en)

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