SU1210789A1 - Method of diagnosis of functional disturbance of gastric secretion - Google Patents

Method of diagnosis of functional disturbance of gastric secretion Download PDF

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Publication number
SU1210789A1
SU1210789A1 SU833627780A SU3627780A SU1210789A1 SU 1210789 A1 SU1210789 A1 SU 1210789A1 SU 833627780 A SU833627780 A SU 833627780A SU 3627780 A SU3627780 A SU 3627780A SU 1210789 A1 SU1210789 A1 SU 1210789A1
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USSR - Soviet Union
Prior art keywords
gastric
diagnosis
histamine
gastric secretion
secretion
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SU833627780A
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Russian (ru)
Inventor
Вилл Васильевич Щедрунов
Сергей Борисович Оникиенко
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Военно-Медицинская Ордена Ленина Краснознаменная Академия Им.С.М.Кирова
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Priority to SU833627780A priority Critical patent/SU1210789A1/en
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Description

Изобретение относитс  к медицине в частности к гастроэнтерологии, и может быть использовано дл  разграничени  функциональной гипо- хилии и ахилии желудка от органической ,The invention relates to medicine, in particular, to gastroenterology, and can be used to distinguish functional hypoxia and ahilia of the stomach from organic,

Цель изобретени  повышение точности способа диагностики за сче проведени  гистамино-зтимизоловой пробы.The purpose of the invention is to improve the accuracy of the diagnostic method by conducting a histamine-optimizol test.

Способ осуществл иуг следующим образом.The method is carried out as follows.

Исследуют желудьчную; секрецию на гистамин, а затем -в качестве стиму л тора парентерально ввод т соче- танно гистамин. в той же дозе и этимизол 1 мг на 1 кг массы, и при повышении концентрации и общей продукции сол ной кислоты на 15% и более по сравнению с первым исследованием считают сниженные исходные показатели следствием функциональных нарушений желудочной секреции.Examine the gastric; histamine secretion, and then - as a stimulant of the torus, histamine is combined parenterally. in the same dose and etimizol 1 mg per 1 kg of weight, and with an increase in the concentration and total production of hydrochloric acid by 15% or more compared with the first study, the reduced baseline results are considered to be a consequence of functional disorders of gastric secretion.

Пример. Больна  51 год, находилась на лечении по поводу хронического гастрита с пониженной функцией желудка, которым страдает в течение последних 3 ле.т, Производ т исследование желудочной секреРедактор М.ТовтинExample. Sick for 51 years, treated for chronic gastritis with reduced gastric function, which has been suffering for the last 3 years, the study of gastric secretary has been done. Editor M. Tovtin

Составитель М.Позн кCompiled by M.Pozn to

Техред Т.Дубинчак Корректор М.МаксимишинецTehred T. Dubinchak Proofreader M. Maksimishinets

Заказ 569/6Тиршс 659 « ПодписноеOrder 569 / 6Tirshs 659 “Subscription

ВНИИПИ Государственного комитета СССРVNIIPI USSR State Committee

по делам изобретений и открытий 113035, Москва, Ж-35, Раушска  наб., д. 4/5for inventions and discoveries 113035, Moscow, Zh-35, Raushsk nab., 4/5

Филиал ШШ Патент, г. Ужгород, ул. Проектна , 4Branch ShSh Patent, Uzhgorod, st. Project, 4

210789210789

ции (простой гистаминовый тест), которое состоит, в аспирации содержимого желудка натощак, затем четырех 15-минутных порций желудочного сока(simple histamine test), which consists in aspirating the stomach contents on an empty stomach, then four 15-minute portions of gastric juice

5 в базальных усло.ви х с последук цим введением гистамииа фосфата (0,008 мг на 1 кг массы тела) и дальнейшей аспирацией четырех 15-минутных порций желудочного сока. Через 35 in the basal conditions with subsequent administration of histamia-phosphate (0.008 mg per 1 kg of body weight) and further aspiration of four 15-minute portions of gastric juice. After 3

10 дн  исследование повтор ют с дополнительным внутримьщ1ечным введением зтимизола в дозе мг на 1 кг м ассы тела больного, непосредственного после извлечени  третьей порции желуJ5 дочного содержимого, т.е. за 30 мин до начала стимул ции гистамином желудочной секреции. Оказалось, что в базальную и стимулированную фазу сол на  кислота в желудочномThe 10th day of the study is repeated with the additional intramuscular administration of optimized dose of mg per 1 kg m of the patient’s body aces, immediately after the third portion of the gastric contents of the stomach has been removed, i.e. 30 minutes before histamine stimulation of gastric secretion. It turned out that in the basal and stimulated phases of hydrochloric acid in the gastric

20 соке не определ лась, концентраци  пепсина составл ла 1,5 г/л. После гистамино-этимизоловой пробы MaKcTi- мальные показатели концентрации сол ной кислоты составл ли 80 ммоль/л,No juice was detected at 20, the pepsin concentration was 1.5 g / l. After the histamino-ethimol sample, the MaKcT minimal concentrations of hydrochloric acid were 80 mmol / l,

25 дебит НС - 6 ммоль/ч, пепсина - 12,0 г/л.25 production rate of NS - 6 mmol / h, pepsin - 12.0 g / l.

Диагноз: функциональное нарушение желудочной секреции,Diagnosis: functional impairment of gastric secretion,

Claims (1)

СПОСОБ ДИАГНОСТИКИ ФУНКЦИОНАЛЬНОГО НАРУШЕНИЯ ЖЕЛУДОЧНОЙ СЕК- -METHOD FOR DIAGNOSTIC OF FUNCTIONAL VIOLATION OF THE GASTRIC SEC- - РЕЦИИ путем исследования функции желудка до и после введения гистамина, отличающийся тем, что, с целью повышения точности способа, функцию желудка определяют по уровню общей секреции соляной кислоты, далее больному вводят внутримышечно этимизол, вновь определяют уровень соляной кислоты и при повышении ее уровня более 15% по сравнению с гистаминовой пробой диагностируют функциональное нарушение желудочной секреции.RECTIONS by examining the function of the stomach before and after the introduction of histamine, characterized in that, in order to increase the accuracy of the method, the function of the stomach is determined by the level of total secretion of hydrochloric acid, then the patient is injected intramuscularly with etimizol, the level of hydrochloric acid is again determined and when its level is increased to more than 15 % compared with histamine breakdown, a functional violation of gastric secretion is diagnosed. SU „.,1210789 >SU „., 1210789> ίί
SU833627780A 1983-07-21 1983-07-21 Method of diagnosis of functional disturbance of gastric secretion SU1210789A1 (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5422350A (en) * 1992-09-10 1995-06-06 Warner-Lambert Company Nitrogen substituted acridine and cytochrome P450 inhibitors and methods of use
US5466696A (en) * 1992-09-10 1995-11-14 Warner Lambert Company Tacrine and cytochrome P450 oxidase inhibitors and methods of use

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Ивашкин В.П. Новые метода исследований и принципы метаболической терапии при хронических заболевани х желудка и 12-перстной кишки, 1978, с. 9. *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5422350A (en) * 1992-09-10 1995-06-06 Warner-Lambert Company Nitrogen substituted acridine and cytochrome P450 inhibitors and methods of use
US5466696A (en) * 1992-09-10 1995-11-14 Warner Lambert Company Tacrine and cytochrome P450 oxidase inhibitors and methods of use

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