SU1202590A1 - Method of producing sodium chlorophyllin - Google Patents

Description

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The invention relates to the pharmaceutical industry, namely to a method for producing chlorophyllin sodium.

The aim of the invention is to increase the yield of the target product.

PRI me R. For 100 kg of resinous substances, 300 l of extraction gasoline are taken and the mixture is heated to 65-70 ° C with stirring. The mixture is settled for 30 minutes and about 20 kg of insoluble resinous substances are poured off (after the distillation of gasoline from them, they are used in the production of chlorophyll-carotene paste). The solution is cooled to 10–20 ° C and set aside for 8–12 hours in order to obtain waxy products. The liquid is drained through the filter. Remaining on the walls of the reaction. The torus waxy substances — pac-i are melted, poured, and combined with filtered products, sent for processing into wax HV9INY.

The filtered liquid is heated to 65-70 b and with stirring, treated with 30% aqueous sodium hydroxide solution to a stable alkaline reaction pH 6-10. The consumption of caustic soda solution is about 14 liters. Saponification time is about 1 hour. At the end of the effluent, 100 liters of hot water are added to the reactor with stirring. Mixtures are allowed to stand. The aqueous layer of the saponified products is drained and washed with 100 liters of gasoline when first washed. The wash gas is combined with a gas bed of the unwashed product and directed

202590

for a supply of proviamine concentrate.

100 liters of gasoline are added to the aqueous layer of the substances, the mixture is heated to 65-70 seconds and a 15% aqueous solution of sulfuric acid is slowly added with stirring until acidic, pH 1-3. After settling for one hour, acidic water is poured first, followed by chlorophyllin raw. The remaining gasoline layer is used to make balsamic paste. The resulting chlorophyllin raw in the amount of 2-2.5 kg per 100 kg of resinous substances is washed with gasoline at 65-70 s and stirring. The residues are then distilled off. solvent and essential oils at a temperature up to, washed with water from unreacted sulfuric acid.

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Washed chlorophyllin from the neutron. Disinfect with an aqueous solution of soda to a pH of 8-10 at 80 ° C in the presence of ethyl 96% alcohol. The ratio of raw chlorophyllin to 20% ethyl alcohol: NaaCOj is 1: 10: 0.5. Neutralization when heated to 80 ° C is carried out for 30 minutes. The resulting solution of chlorophyllin sodium is cooled to, filtered and packaged.

The proposed method allows, in comparison with a known method, to increase the yield of the target product by 3 times while maintaining the amount of the product obtained and to significantly increase the throughput of the reaction equipment.

Editor V.Ivanova

Compiled by L.Pashchuk Tehred S. Mig u new

Order 8345/5 Circulation 721

VNISHI USSR State Committee

for inventions and discoveries 113035, Moscow, Zh-35, Raushsk nab., 4/5

Branch PPP Patent, Uzhgorod, st. Project, 4

Washed chlorophyllin from the neutron. Disinfect with an aqueous solution of soda to a pH of 8-10 at 80 ° C in the presence of ethyl 96% alcohol. The ratio of raw chlorophyllin to 20% ethyl alcohol: NaaCOj is 1: 10: 0.5. Neutralization when heated to 80 ° C is carried out for 30 minutes. The resulting solution of chlorophyllin sodium is cooled to, filtered and packaged.

The proposed method allows, in comparison with a known method, to increase the yield of the target product by 3 times while maintaining the amount of the product obtained and to significantly increase the throughput of the reaction equipment.

Proofreader I.Zrdeyi Subscription

Claims (1)

METHOD FOR PRODUCING SODIUM CHLOROPHIPLIN by extraction of coniferous paws with gasoline, sedimentation of the solution, sodium hydroxide treatment, separation of unsaponifiable products, washing of saponified products with gasoline. decomposition (sulfuric acid, sedimentation and separation of raw chlorophyllin, characterized in that, in order to increase the yield of the target product, the gasoline extract of resinous substances before saponification is concentrated to 25-30% by distillation of gasoline, and the decomposition of saponified products with acid and the allocation of raw chlorophyllin carried out in the presence of gasoline with a phase ratio of gasoline-saponified products->