SU1019810A1 - Methyl ester of 5(6)-/1-(2n)-phthalasionyl-4/-1n-benzaimidozolyl-2-carbamic acid displaying antihelminth activity - Google Patents

Methyl ester of 5(6)-/1-(2n)-phthalasionyl-4/-1n-benzaimidozolyl-2-carbamic acid displaying antihelminth activity Download PDF

Info

Publication number
SU1019810A1
SU1019810A1 SU813350497A SU3350497A SU1019810A1 SU 1019810 A1 SU1019810 A1 SU 1019810A1 SU 813350497 A SU813350497 A SU 813350497A SU 3350497 A SU3350497 A SU 3350497A SU 1019810 A1 SU1019810 A1 SU 1019810A1
Authority
SU
USSR - Soviet Union
Prior art keywords
activity
methyl ester
carbamic acid
phthalasionyl
benzaimidozolyl
Prior art date
Application number
SU813350497A
Other languages
Russian (ru)
Inventor
Ф.С. Михайлицын
Б.П. Тимошевский
В.И. Шведова
Э.В. Переверзева
Н.Л. Веретенникова
М.Н. Лебедева
Original Assignee
Институт медицинской паразитологии и тропической медицины им.Е.И.Марциновского
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Институт медицинской паразитологии и тропической медицины им.Е.И.Марциновского filed Critical Институт медицинской паразитологии и тропической медицины им.Е.И.Марциновского
Priority to SU813350497A priority Critical patent/SU1019810A1/en
Application granted granted Critical
Publication of SU1019810A1 publication Critical patent/SU1019810A1/en

Links

Abstract

Метиловый эфир 5Methyl ester 5

Description

про вил эффективность 82%, а к 60 дню 57%. В ближайшее после введени  препарата врем , т.е. через 35 дней, гельиинтоцйдна  активность Г-1135 превышает активность пр1епарата тиабендазол . При введении Г-1135 на мышечной фазе трихинешгеза трихинеллоцидна  активность Г-1135 (41%) по активности приближалась к активности тиабендазола (49%).The efficiency was 82%, and by day 60 it was 57%. At the earliest time after dosing, i.e. after 35 days, the geliintocydine activity of G-1135 exceeds the activity of the thiabendazole preparation. With the introduction of G-1135 in the muscular phase of trichinosis, the trichinelocidal activity of G-1135 (41%) in activity approached the activity of thiabendazole (49%).

В данные сроки мыши не вскрьюались.In this timeline, the mice did not open.

Claims (1)

Метиловый эфир 5(6)-ζΐ (2Н)-фталазинонил-4^] -1 Н-бензимидазолил-2-карбаминовой кислоты формулыMethyl ester of 5 (6) -ζΐ (2H) -phthalazinonyl-4 ^] -1 H-benzimidazolyl-2-carbamic acid of formula обладающий антигельминтной активностью.possessing anthelmintic activity. N ·N · Λ-ΝΗΟΟΟΟΗ'Λ-ΝΗΟΟΟΟΗ ' (I)(I) антигельминтной актив-anthelmintic active
SU813350497A 1981-07-28 1981-07-28 Methyl ester of 5(6)-/1-(2n)-phthalasionyl-4/-1n-benzaimidozolyl-2-carbamic acid displaying antihelminth activity SU1019810A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SU813350497A SU1019810A1 (en) 1981-07-28 1981-07-28 Methyl ester of 5(6)-/1-(2n)-phthalasionyl-4/-1n-benzaimidozolyl-2-carbamic acid displaying antihelminth activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SU813350497A SU1019810A1 (en) 1981-07-28 1981-07-28 Methyl ester of 5(6)-/1-(2n)-phthalasionyl-4/-1n-benzaimidozolyl-2-carbamic acid displaying antihelminth activity

Publications (1)

Publication Number Publication Date
SU1019810A1 true SU1019810A1 (en) 1991-04-07

Family

ID=20981281

Family Applications (1)

Application Number Title Priority Date Filing Date
SU813350497A SU1019810A1 (en) 1981-07-28 1981-07-28 Methyl ester of 5(6)-/1-(2n)-phthalasionyl-4/-1n-benzaimidozolyl-2-carbamic acid displaying antihelminth activity

Country Status (1)

Country Link
SU (1) SU1019810A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016187620A3 (en) * 2015-05-21 2017-05-04 The Regents Of The University Of California Anti-cancer compounds
US10640493B2 (en) 2016-06-24 2020-05-05 The Regents Of The University Of California Phthalazine derivatives as inhibitors of PARP1, PARP2, and/or tubulin useful for the treatment of cancer

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Европейский патент № 9174, ,кл. С 07 D 401/02, опублик 1980. Патент US № 3055907, кл„ 260-302, опублико 1962. *

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016187620A3 (en) * 2015-05-21 2017-05-04 The Regents Of The University Of California Anti-cancer compounds
EP3298005A4 (en) * 2015-05-21 2019-02-13 The Regents of The University of California Anti-cancer compounds
US10562886B2 (en) * 2015-05-21 2020-02-18 The Regents Of The University Of California Anti-cancer compounds
US11149025B2 (en) 2015-05-21 2021-10-19 The Regents Of The University Of California Anti-cancer compounds
US11708352B2 (en) 2015-05-21 2023-07-25 The Regents Of The University Of California Anti-cancer compounds
US10640493B2 (en) 2016-06-24 2020-05-05 The Regents Of The University Of California Phthalazine derivatives as inhibitors of PARP1, PARP2, and/or tubulin useful for the treatment of cancer
US11072600B2 (en) 2016-06-24 2021-07-27 The Regents Of The University Of California Phthalazine derivatives as inhibitors of PARP1, PARP2, and/or tubulin useful for the treatment of cancer

Similar Documents

Publication Publication Date Title
ES2061432T3 (en) NEW ACRYLIC ACID AMIDES.
NO851170L (en) STORAGE STABLE, QUICK-DESTROYING PHARMACEUTICAL ACTIVE SUBSTANCE PRESSURES
EP0176033A3 (en) Isoxazolecarboxylic-acid derivatives, their preparation and use
GEP20032938B (en) Acaricide
NL192343B (en) 17O-substituted androsta- (1,) 4- (di) en-3-on-17β-carboxylic acid compounds with anti-inflammatory activity and pharmaceutical compositions containing these compounds.
NZ185745A (en) Insecticidal and repellant shampoos containing acetic acid
IT8221278A0 (en) PHARMACEUTICAL COMPOSITION CONTAINING 24,25-DIHYDROXYCHOLECALCIFEROL AS ACTIVE INGREDIENT
ATE84045T1 (en) INHIBITING SUBSTANCES ENKEPHALINASE-B THEIR PREPARATION AND THEIR PHARMACEUTICAL COMPOSITIONS.
SU1019810A1 (en) Methyl ester of 5(6)-/1-(2n)-phthalasionyl-4/-1n-benzaimidozolyl-2-carbamic acid displaying antihelminth activity
IT8047619A0 (en) DERIVATIVES OF 6-ALKYL-1,2DIHYDRO-2-OXONICOTINIC ACID WITH ANTIHYPERGLYCEMIC ACTIVITY
IT8021550A0 (en) ADENOSINE DERIVATIVES WITH ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY AND THERAPEUTIC COMPOSITIONS WHICH CONTAIN THEM AS THE ACTIVE INGREDIENT.
JPS5396388A (en) Preparation of l-phenylalanine
EG14021A (en) Fungicidally an nematocidally active 1,3,4-thiadiozole-2-carboxylic acid derivatives and their manufacture and use
DK136250C (en) INSECTICIDES AND ACARICIDES ACTIVE 0-ETHYL-S-N-PROPYL-0- (PYRIDAZ- (3) -ON- (6) -YL) -THIONOTHIOLPHOSPHORIC ACID RESIDENTS
JPS5495737A (en) Stabilized composition containing carpronium chloride
IT8021037A0 (en) INSECTICIDE COMPOSITIONS WHICH ACID SUBSTITUTED ESTERS CONTAIN THE SAME AS CYCLOPROPANCARBOXYL AND ACTIVE INGREDIENT.
DK137129B (en) INSECTICIDES AND ACARICIDES ACTIVE O-PHENYLTHIONOTHIOLPHOSPHORIC ACID RESIDENTS
JPS5334752A (en) Preparation of gamma-ionones and their derivatives
JPS52139057A (en) Substituted propionic acid and medicine containing same as active ingredient
ES8105250A1 (en) Substituted decalins, their preparation and use.
JPS5251899A (en) Dispaly rack assembling device
IT7822999A0 (en) PROCEDURE TO SEPARATE 11-CYANOUNDECANOIC ACID, CYCLOHEXANOME AND E-GOAT-LACTAM.
IT1142639B (en) THERAPEUTIC COMPOSITIONS WITH COLERETIC ACTIVITIES CONTAINING AS ACTIVE INGREDIENT DERIVED FROM COLANIC ACID
JPS53133206A (en) Liquid shampoo composition
IT8421470A0 (en) DERIVATIVE OF PYRROLCARBOXYLIC ACID WITH ANALGESIC ACTIVITY, ITS PREPARATION AND COMPOSITIONS THAT CONTAIN IT.