SK278298B6 - Veterinary composition for treatment of digestion disorders of ruminants - Google Patents

Abstract

The preparation contains of sodium propionate 50,0 up to 120,0 g, beer yeast 35,0 g up to 90,0 g in a spray form, tri-sodium citrate 1,0 up to 6,0 g, citric acid 1,5 up to 3,5 g, calcium hydrogen phosphate 18,0 up to 42,0 g, sodium chloride 5,0 up to 12,0 g, cobalt (II) sulphate 0,01 up to 0,1 g, manganese (II) sulphate 0,05 up to 0,2, copper (II) sulphate 0,05 up to 0,3 g, iron (II) sulphate 0,05 up to 0,3 g, zinc sulphate 0,005 up to 0,2 g.

Description

Technical field

The present invention relates to a veterinary preparation for the treatment of digestive disorders in ruminants of the ruminants, disorders of the energy metabolism in the ruminant organism, and for restoring the utility of these animals.

BACKGROUND OF THE INVENTION

Current veterinary preparations for the treatment of digestive disorders in the rumen of ruminants are based on the principle of the glucogenic action of propionates (J. Dairy Sci., 60, 1977, JM Young, Gluconeogenesis in cattle: Significance and methodology, pp. 1-15, G. Dirksen, Indigestions in cattle, ¹ , Schnetzor-Verlang, GmbH, Konstantz, 1983, pp. 31-32).

The veterinary preparation PRODIGESTAN, described in the List of Veterinary Preparations Spofa, Prague 1988, p. 155, which is based on sodium propionate, calcium propionate, manganese sulfate, copper sulfate, zinc sulfate and cobalt chloride. A similar composition has another BYKODOGEST veterinary preparation described in Präparateliste ad usum veterinarum, Byk Gulden Pharmazeutika, Konstanz, 1985, p. 15, which is based on sodium propionate, calcium propionate, sodium chloride and salts containing cobalt, copper, manganese, iron, zinc and molybdenum. In the digestive disorders caused by the disruption of the secretory activity of the digestive tract, a magnesium and aluminum silicate preparation is also used, which is described in DE 1767994 C2, D. Luis, C. Pohlau, F. Lohrentz, Arzneimittel mit antacid und absorbtivem, Wirkstoff.

The disadvantage of the existing veterinary preparations of our and foreign products is that they do not contain certain substrates, such as biologically active substances and minerals, which are necessary for optimal development of microflora and microfauna in the rumen of ruminants and for optimizing the metabolism and corresponding performance.

SUMMARY OF THE INVENTION

Veterinary preparation for the treatment of ruminant disorders according to the invention based on spray yeast, propionate and sodium citrate, calcium phosphate and microelements, which consists of containing 50.0 to 120 g of sodium propionate, 35.0 to 90.0 g of spray beer yeast, 1.0 to 6.0 g trisodium citrate, 1.5 to 3.5 g citric acid, 18.0 to 42.0 g calcium hydrogen phosphate, 5.0 to 12.0 g sodium chloride, 0.01 up to 0.1 g of cobalt sulfate, 0.05 to 0.2 g of manganese sulfate, 0.05 to 0.3 g of copper sulfate, 0.05 to 0.3 g of ferrous sulfate, 0.005 to 0.2 g of zinc sulfate. Preferred amounts of the ingredients of the composition are 90.0 g sodium propionate, 45.0 g spray yeast, 4.0 g trisodium citrate, 1.1 g citric acid, 22.0 g calcium hydrogen phosphate, 7.5 g sodium chloride, 02 g of cobalt sulphate, 0.12 g of manganese sulphate, 0.15 g of copper sulphate, 0.10 g of ferrous sulphate, 0.01 g of zinc sulphate.

The content and proportions of these components are particularly important for creating an optimal environment and for the development of microflora and microfauna in the rumen, as well as for the proper motoring of the stomachs, to ensure the need and production of B group vitamins. energy metabolism and ensures restoration of the animal's performance. The composition according to the invention has a wide application especially in the treatment and prevention of ketoses, liver diseases, indigestions, feverish conditions and after surgical interventions in ruminants, especially dairy cows. The composition is readily soluble in water in powder form.

The new veterinary preparation for treating ruminant digestive disorders compared to prior art preparations contains yeast spray yeast, sodium citrate and dibasic calcium phosphate. The advantage of the new preparation lies mainly in the use of beer yeast, which is a source of nutritional and biologically active substances 20 necessary for the development of rumen fermentation processes.

The content of sodium citrate and calcium bicarbonate ensures better utilization of ruminant digestive metabolites. The new preparation thus significantly contributes to increasing the efficiency of milk and meat production.

DETAILED DESCRIPTION OF THE INVENTION

The veterinary preparation for the treatment of digestive disorders of 30 ruminants is in powder form and the preferred amount of the preparation components is 90.0 g sodium propionate, 45.0 g spray yeast, 4.0 g trisodium citrate, 1.1 g citric acid, 22.0 g of dicalcium phosphate, 7.5 g of sodium chloride, 0.02 g of barium sulfate, 0.12 g of manganese sulfate, 0.15 g of copper sulfate, 0.10 g of iron sulfate, 0.01 g of zinc sulfate.

Mixing a preferred amount of the individual components yields a single portion weighing 170-40g. The whole dose, or a portion thereof, is mixed in lukewarm water or chamomile tea and administered orally by means of a bottle or an esophagus tube. The composition can be administered with loose feed as a compound feed formulation.

Dosage of the preparation according to the invention is either therapeutic - adult bovine 1 dose (170 g) in 1 to 2 liters of lukewarm water twice a day for 3-5 days, calf, sheep, goat 1/5 dose in 0.5 1 warm chamomile tea or lukewarm water twice a day for 3-5 days, 50 or preventive - adult cattle 1 dose 1x daily several days before delivery and within 2 to 3 weeks postpartum mixed with loose feed, calf, sheep, goat 1/5 dose 1x daily for 7 days.

Industrial use

The powder formulation is used in veterinary medicine to treat digestive disorders.

The preparation is indicated for ketoses, hepatopathies, digestive disorders in the stomach, acidosis and alkalis of rumen after previous rumen pH adjustment, sudden changes in feed ration, 65 for feeding of low-quality feeds, lack of easily fermented carbohydrates in rations, , in feverish conditions (mastitis, endometritis) and in convalescence after surgery, e.g. after rumenotomy.

Claims (2)

A veterinary preparation for the treatment of ruminant digestive disorders, characterized in that the mixture comprises 50.0 to 120.0 g of sodium propionate, 35.0 to 90.0 g of spray beer yeast, 1.0 to 6.0 g of trisodium citrate 1.5 to 3.5 g citric acid, 18.0 to 42.0 g calcium hydrogen phosphate, 5.0 to 12.0 g sodium chloride, 0.01 to 0.1 g cobalt sulfate, 0.05 to 0 g 2 g of manganese sulfate, 0.05 to 0.3 g of copper sulfate, 0.05 to 0.3 g of ferrous sulfate, 0.005 to 0.2 g of zinc sulfate. Veterinary preparation according to claim 1, characterized in that the mixture comprises 90.0 g of sodium propionate, 45.0 g of spray yeast, 4.0 g of trisodium citrate, 1.1 g of citric acid, 22.0 g of calcium hydrogen phosphate 7.5 g of sodium chloride, 0.02 g of cobalt sulfate, 0.12 g of manganese sulfate, 0.15 g of copper sulfate, 0.10 g of ferrous sulfate, 0.01 g of zinc sulfate.