SI8710853A - Improved capsule - Google Patents
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- SI8710853A SI8710853A SI8710853A SI8710853A SI8710853A SI 8710853 A SI8710853 A SI 8710853A SI 8710853 A SI8710853 A SI 8710853A SI 8710853 A SI8710853 A SI 8710853A SI 8710853 A SI8710853 A SI 8710853A
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Abstract
Pokrov želatinaste kapsule ima prstenast žleb v delu odprtega konca zaradi zmanjšanja ovalnosti.The capsule of the gelatin capsule has a annular groove in part of the open end to reduce ovality.
Description
Pronalazak ee odnosi na onu vrstu kapsula koja se sestoji od uglavnom cilindrično# dola tela i poklopca koji se teleskop» skl postavlja na telo, a posebno se odnosi na vratu tvrdih žela» tinskih kapsula koje se šesto koriste aa punjenje faraaoeutskia preparatima·The invention ee relates to a type of capsule consisting mainly of cylindrical cylindrical bottoms and a lid which is telescopically folded onto the body, and in particular relates to the neck of hard gelatine capsules frequently used for the filling of pharaaoeut preparations ·
Tvrde Želatinske kapsule prave se Is dva dela saronjavanjem Seličnih stubiča u istopijeni rastvor želatina, formiranjem 1 su» Senjem želatina i skidanjem formiranih školjki sa stublča·Hard gelatin capsules are made of two parts by dropping Selicic columns into molten gelatin solution, forming 1 are »Shading gelatin and removing formed shells from the stem ·
OpŠte je posnato da se film želatina pri sušenju skuplja· Kontrola vlažnosti u toku i posle operacije sušenja kritična je sa dlmensionalnu stabilnost formiranih kapsula· Skupljanjo sevi» si od broja faktora, kao količine vode koju trba ukloniti, vrste upotrebljenog želatina, režima sušenja i broja 1 vrste dodataka, kao Sto au boje 1 površinski aktivna jedinjenja· Kapsule gube još do $$ vlage posle skldanja sa stubiča, na kojima su se for» mlrale·It is generally recognized that the gelatin film shrinks during drying · Moisture control during and after the drying operation is critical with the dlmensional stability of the capsules formed · The shrinkage of the number of factors such as the amount of water to be removed, the type of gelatin used, the drying regime and the number 1 types of additives, such as Sto au Colors 1 surfactants · Capsules lose up to $$ of moisture after stripping off the stairs, which are for
Efekat promena uslova sušenja i sestava želatina vodi do promena prečnika formiranih i suvih Školjki· Zatim efekat toka želatina u sudu sa uronjavanje, zajedno aa konusnlm stublČisa i sogučia prieuetvora profila koji obesbedjuju spajanje polovina kapsula, komblnovano aa sistemom sušenja koji usrokuje da presek suve kapsule ne bude okrugao, pravi ovalni otvor«The effect of changes in drying conditions and composition of gelatin leads to changes in the diameter of formed and dry shells be round, a real oval opening «
Jedan od efekata te ovalnosti je da pravi teškoče pri epa» jenju dveju polovina kapsule· Kesto teleskopsko# uvlačenja jed» ne u drogu, dve polovine mogu se uvučl do neke granice, us so * gučnost proeipanja jedne 111 obe polovine kapsule, sa trenutnim ili kasnijlm gubljenja« sadržaja kapsule·One of the effects of this ovality is that it makes it difficult to fit two halves of the capsule. • Frequently telescopically pulling the mast into the mast, the two halves can be pulled up to some limit, with the difficulty of collapsing one or both halves of the capsule, with the current or later loss of «capsule content ·
Vrženi su napori da ae problemi ovalnosti prevasldju, napr. prosenem oblika· Ipak, do sada nije bilo moguče da se nadje sa» dovoljavajuče rešenj e problema i merenj» vržena na veličini 1 poklopca kapsule prečnika 6*9 mm pokesala su da ovalno st, odredjena merenje« razlike izmedju največlh i najmanjih prečnika, Is» nosi do 0*5 mm, bes obzira na proizvodjača kapsula*Efforts have been made to overcome oval problems, for example. · However, it has not been possible so far to find with "sufficient problem solving and measurement" thrown on the size of a cap of capsule 6 * 9 mm in diameter that the oval position, a certain measurement "of the difference between the largest and smallest diameters, Is »Carries up to 0 * 5 mm, regardless of capsule manufacturer *
-2Pronalazak predvidja r®Sonje problema ovalnosti no menja juči nalove formiranja i gašenja kapsulo·-2 Finding Predicts r®Songe Oval Problems But Changes the Capsule Formation and Quenching Yesterday ·
Ovaj pronalasak predvidja da školjka kapsulo ima prstenast žleb u delu otvorenog kraja« Poželjno je da je Žleb na poklopou.The present invention provides that the capsule shell has a annular groove in the portion of the open end. "Preferably, the groove is on the lid.
»boo otvorenog kraja” enači da ae nalazi blizu otvorenog kraja, tj« ne dalje od 2 ma, poželjno izmedju 0.5 mm i 1*5 sta od sečenog kraja, u zavisnosti od veličine kapsule·"Open end boo" equates to being near the open end, ie "no further than 2 mA, preferably between 0.5 mm and 1 * 5 in. From the cut end, depending on the size of the capsule.
Prisustvo prestenastog žleba dozvoljava da ee film kapsule suši pri normalnim ueloviaa, uz mnogo smanjenu mogučnost etva* ranja ovala« Sod kapsule veličine 1 napr. najbolje je postaviti žleb na rastojanju od oko 0.5 ®m do oko 1*6 sm od otvorenog kraja školjke« Žleb treba da bude neprekidan. Ipak, moguče je postiči smanjenje ovalnosti upotrebom eegmentnog žleba, napr* od oko 2 do oko 12 segmenata. Segmenti bi trebalo da okruže najtanje oko 90$ obima školjke« Tipično je da je Širino Žleba od okoThe presence of a slotted groove allows the capsule film to dry at normal angles, with a much reduced possibility of forming an oval. it is best to place the groove at a distance of about 0.5 ®m to about 1 * 6 cm from the open end of the shell. “The groove should be continuous. However, it is possible to achieve a reduction in ovality by using a segmental groove, for example, from about 2 to about 12 segments. Segments should surround the thinnest about $ 90 shell volume «Typically, the Groove Width of about
Poprečni presek Žleba može biti kriv ili ugaoni i može ee menjati prema obliku, napr« od jednostruke do višestruke veličine prečnika, Ui da bude u obliku V, do višeugaonih oblika, kao kvadratnog, pravougaonog ili trapeznog.The groove cross-section may be curved or angular and may vary in shape, eg from single to multiple diameter, Ui to be in shape V, to polygonal shapes, as square, rectangular or trapezoidal.
Pronalazak če ee bolje razumeti uz priložen ortež, gde sl.1 prikazuje neobavezno poklopac kapsule urad j en prema pronalasku, a sl« 2 prikazuje uvedene oblike detalja označenog se A ne sl.1«The invention will be better understood by the enclosed orbit, wherein FIG. 1 shows optionally a capsule lid made according to the invention, and FIG. 2 shows embodiments of the details marked A not FIG. 1. "
Sl« 1 prikazuje deo poklopca kapsule veličine X« Ukupna du5žina poklopca kapsule veličine 1 iznosi 10 mm« Žleb dubine O.o2 aa i Širine 0«5o as formiran je ea sredižtem na raetojanju 1*3 ss od scčenog kraja« Poklopac je formiran na atubiču odgovara * jučeg profila»Fig «1 shows part of capsule cover of size X« Total length of capsule cap of size 1 is 10 mm «Groove of depth O.o2 aa and Width 0« 5o as formed ea centered at a distance of 1 * 3 ss from the closed end «The cover is formed on attubichu fits * yesterday profile »
Oblik poprečnog preseka žleba seže biti aa koji« več usvojeni, a sl. 2 prikasuje niz odgovarajučih oblika poprečnog pre« seka žleba, koji ee aogu koristit, a koji nije konačan.The cross-sectional shape of the groove can be aa already adopted, and Figs. 2 bevels a series of suitable cross-sectional shapes of grooves which may be used but not finite.
Školjke kapsule preša pronalasku mogu imati druge oblike, kao napr. oblik satvaranja, prema britanskim patentiaa 970761, 1040859 i 1442121.The shells of the capsule of the invention may take other forms, such as e.g. clockwork, according to British patentiaa 970761, 1040859 and 1442121.
8a druge strane poam&trano, pronalazak se odnosi i na stubič koji ima prstenast žleb pogodan ea pravljenje Školjke kapsule prema pronalasku.8a. On the other hand, the invention also relates to a bar having a annular groove suitable for making a Shell Capsule according to the invention.
Vržena je serija proba da se naprave lelatinski poklopci razUčltib oblika, koji eadrže ili 2 »PRE-IOK» (saStitai trgo« vački znak) foraacije, ili 4 PRS-IOK formacije (videti brit« anski patent 1442121). Poklopci se prave sa žlebom O.o2 ma, prikazano na sl. 9.A series of tests were conducted to make lellatin lids of discernable shape, which contained either 2 PRE-IOK formations or 4 PRS-IOK formations (see British patent 1442121). The covers are made with a groove O.o2 ma, shown in fig. 9.
ESSSžJ.ESSSžJ.
Poklopci kapsula veličine 1 napravljeni su aa 2 PRE—LOKM formscijom i pratenastla žlebom, kao Sto je ranije opisano* Bi« multano su napravljeni i poklopci kapsula veličine 1 sa 4 PRELOK formacijo«, ali bez prstenastog žleba« Uzorak od po $0 po« klopaca od obe vrste uzet je pri reletivnoj vlažnosti od 15%· Ovelnost svakog poklopca odredjena je merenjea največeg i naj« manjeg prečnika i odredjivanjem razlike« Za standardne poklopca srednja ovalnoet bila je 0«127 mm, dok je za kapsule sa krožnim Žlebom srednja ovalnoet smanjena na C«o89 mm.The caps of capsules of size 1 were made aa 2 PRE-LOK M formation and followed by a grooved groove, as previously described * Bi «the capsules of size 1 with 4 PRELOK formation were also made, but without a groove« Pattern of $ 0 per « flaps of both types were taken at a relative humidity of 15% · The circumference of each flap was determined by measuring the largest and smallest diameter and determining the difference. For standard flaps the mean oval was 0 «127 mm, while for circular groove caps the median oval was reduced to C «o89 mm.
Gornja proba napravljena je pod posebnim uslovima i uzorci au uzeti pri relativno j vlažnosti 14,5%. standardne kapsule po« kazale su srednju ovalnoet od 0.132 mo, dok su kapsule sa prst« enastim žlebovima imele srednju ovalnoet samo 0«©79 mm.The above test was made under special conditions and samples were taken at a relative humidity of 14.5%. the standard capsules showed a mean ovale of 0.132 mo, while the capsule with ring grooves had a median ovale of only 0 "© 79 mm.
iaisJiaisJ
Poklopci kapstla veličine 1 napravljeni su sa 2 “FRS-LOK forma©ijom i sa prstenasti® žlebovima keo prema probi 1. Siaul« tene su napravljeni poklopci kapsula standardne veličine 1 sa pab-LOK* formacijama i ea P06ILCK (zaStitni trgovački znak) formacijo®» prema britanskem patentu 1442121» ali boa prstana« stog »loba« Pedeset usoraka pcsmatrano ja od evekih» pri naleti vnoj vlažnosti 14.63 i morena je ovalnoot kao u probi 1· Stan* dardni POSILOK poklopci imali su srednju ovalnost 0»lo2 mm» dok su poklopci kapsule prema pronalasku imali srednju ovanlnost samo O.e62 mm*The size 1 capsules are made with 2 "FRS-LOK Shapes and with ring® grooves keo according to test 1. Siaul« tene caps are made of standard size 1 capsules with pub-LOK * formations and ea P06ILCK (Trademark) Formation ® »according to British patent 1442121» but the color of the ring is a "stack" of the forehead "Fifty dents pcs considered more than ever" at an incident humidity of 14.63 and the oval was oval as in test 1 while the capsules of the invention according to the invention had a mean circumference of only O.e62 mm *
Bmanjenje ovalnosti kapsula» prosa pronalasku» olakžava rad sa saSinom» kao sortiranja» punjenja 1 spajanje» a poboljšava i apa^panje. 2bog poboljŠanog spajanja omenjena je toleran olja ogrsničernja u proizvodnji» Sto rezeultuje boljim spajanjem tela i poklopca i smanjenim slučajnim odvajanjem polovina kap aule poale punjenja.Reducing the ovality of the capsules »millet invention« makes it easier to work with the son »as sorting» filling 1 joining »and improves the apa ^ sting. For the sake of improved jointing, the tolerance of crude oil in production has been mentioned »which results in a better connection of the body and the lid and a reduced accidental separation of the half caps of the filling tank.
cesto se želi da ee zalepi traka na epejenu kapoulu» kako bi se izbeglo curenje u slučaju tečnog sardžaja» ili da kapsula bude obeležena za nasilno otvaranje» ili otporne na isto» ili radi identifikacije. Cvo se može postiči upotrebom poznatih postupaka i opreme» kao Sto je Quali~Seal mašina (1’anufacturing Cheaist» dan« 193?» str. 27). U ovim uslovima poklopac kapsule ea žlebom ima iznenadjujuče prednosti pri povezivanju sa trakom za spajanje» a posebno je koristen kada kapsula sadrži tečno punjenje» Prvo» omenjen® ovalnost poklopca ne samo da ol&kšava postupak sa mašinoa» tj» ublažava obrtanja 1 emanjuje neste bilnoet pri obrtanju na načini za zatvaranje psi postavljanju trake sa spajanje» več Sto je ječ važnije» utiče da je razmak po obimu poklopca i tela kapsule ujednačenlji» nego što je kod kapsule konvencionalno^ oblika» Kada se traka za spajanje» kao što je že latinska» postavi izmedju kraja poklopca i tela kap sule razmak koji traka treba da premosti ujednačenlji je i dozvoljava tačnije spajanje» istovremeno dozvoljavajučl da se može upotrebiti tanja Selatinska traka za spajanje» Drugo» rav nemarnost razmaka po obimu» a prema gore Izleženo®» zajedno sa boljim dimenzionim ulclapenjem 1 dodatno» aadržavajudom grenlcom koji se poetižu postupkom prema pronalasku» obezbedjuju dodatne prednosti» kada kapsula treba da sadrži malo viskozna tečnost» •5kao ulj® jagerževine* 17 ovi» kapsulama koja sadrže tečnost pot· robno ja spražiti curecjo retkog ulja ili druge težnosti u oko· licu zatvaranje® trkaom» ili drugi® tehnikama* Ako so pogreši u sprečavanju ourenja u toku 5*10 min posla punjenja» u koa vre· senu aapunjeno kapsule mogu biti sortirane i »ažinoa postavljena u pravilen položaj za spajanja» graška spajanja kapsula čire se u oslu zenu kontakta» uz rizlk daljeg ourenja sadrŽcja is kap sula. iznenadjujuče ja naznanja da sa na tastu od pola siliona kapsula napunjenih uljem jagorževine videle ds ja satanjenje eu· ranja sadržaj a kapsula bilo rezultat upotrebe poklopca sa pr · stenastira žlebom» a prema pronalasku«it is often desirable that the tape be glued to the epee capsule "to avoid leakage in the case of liquid contents" or that the capsule be marked for forced opening "or resistant to the same" or for identification. This can be achieved by using known procedures and equipment "such as What is a Quali ~ Seal Machine (1'anufacturing Cheaist" Day "193?" P. 27). In these conditions, the cap of the ea groove cap has surprising advantages in connection with the coupling strip "and is especially useful when the capsule contains liquid filling" The first "mentioned® oval capability not only facilitates machine operation" i.e. rotating in a way to close the psi by placing a lanyard tape "more What is more important" makes the distance between the circumference of the cap and the body of the capsule more uniform "than in the case of a capsule conventionally ^ in the form of" When the lanyard is "such as Latin" place between the end of the lid and the drip body the distance that the strap should bridge is more uniform and allows a more accurate fitting »while allowing a thinner Selatine strap to be used» Other »evenly spaced by volume» upwards Exposed® »together with better dimension locking 1 additionally »retaining bushings which are recovered by the process of the invention» provide have additional advantages »when the capsule should contain a little viscous liquid» • 5 as oil * fats * 17 these »capsules containing liquid · need to discharge a leak of a rare oil or other gravity in the eye · by closing with a« race »or other ® techniques * If the salt prevents leakage during the 5 * 10 min filling job »at which time the augmented capsules can be sorted and» placed in the correct position for the joints »the capsule of the capsule junction spreads to the contact surface» with the risk of further leaching of the contents and a drop of sul. surprisingly, I announce that with a half-silion capsule filled with lava oil oil, I saw the wrinkling of the contents and the capsule was the result of the use of a ring with a groove "according to the invention"
Claims (14)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB868611905A GB8611905D0 (en) | 1986-05-15 | 1986-05-15 | Capsules |
YU85387A YU47261B (en) | 1986-05-15 | 1987-05-13 | Capsules shell and gelatin capsules |
Publications (2)
Publication Number | Publication Date |
---|---|
SI8710853A true SI8710853A (en) | 1997-02-28 |
SI8710853B SI8710853B (en) | 1998-06-30 |
Family
ID=26290774
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI8710853A SI8710853B (en) | 1986-05-15 | 1987-05-13 | Improved capsule |
Country Status (2)
Country | Link |
---|---|
HR (1) | HRP940191B1 (en) |
SI (1) | SI8710853B (en) |
-
1987
- 1987-05-13 SI SI8710853A patent/SI8710853B/en unknown
-
1994
- 1994-03-24 HR HR940191A patent/HRP940191B1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
HRP940191A2 (en) | 1996-04-30 |
SI8710853B (en) | 1998-06-30 |
HRP940191B1 (en) | 2000-12-31 |
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