SI2450035T1 - Combination of adapalene and benzoyl peroxide for treating acne lesions - Google Patents

Combination of adapalene and benzoyl peroxide for treating acne lesions

Info

Publication number
SI2450035T1
SI2450035T1 SI200732094T SI200732094T SI2450035T1 SI 2450035 T1 SI2450035 T1 SI 2450035T1 SI 200732094 T SI200732094 T SI 200732094T SI 200732094 T SI200732094 T SI 200732094T SI 2450035 T1 SI2450035 T1 SI 2450035T1
Authority
SI
Slovenia
Prior art keywords
adapalene
combination
benzoyl peroxide
treating acne
acne lesions
Prior art date
Application number
SI200732094T
Other languages
Slovenian (sl)
Inventor
Vernet Marie-Line Abou-Chacra
Denis Gross
Christian Loesche
Michel Poncet
Original Assignee
Galderma Research & Development
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37763873&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI2450035(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Galderma Research & Development filed Critical Galderma Research & Development
Publication of SI2450035T1 publication Critical patent/SI2450035T1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/327—Peroxy compounds, e.g. hydroperoxides, peroxides, peroxyacids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
SI200732094T 2006-07-13 2007-07-12 Combination of adapalene and benzoyl peroxide for treating acne lesions SI2450035T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0652968A FR2903603B1 (en) 2006-07-13 2006-07-13 COMBINATION OF ADAPALENE AND BENZOLEO PEROXIDE IN THE TREATMENT OF ACNE
US83349106P 2006-07-27 2006-07-27
EP12152317.9A EP2450035B1 (en) 2006-07-13 2007-07-12 Combination of adapalene and benzoyl peroxide for treating acne lesions

Publications (1)

Publication Number Publication Date
SI2450035T1 true SI2450035T1 (en) 2019-03-29

Family

ID=37763873

Family Applications (2)

Application Number Title Priority Date Filing Date
SI200732094T SI2450035T1 (en) 2006-07-13 2007-07-12 Combination of adapalene and benzoyl peroxide for treating acne lesions
SI200731283T SI2046318T1 (en) 2006-07-13 2007-07-12 Combination of adapalene and benzoyl peroxide for treating inflammatory acne lesions

Family Applications After (1)

Application Number Title Priority Date Filing Date
SI200731283T SI2046318T1 (en) 2006-07-13 2007-07-12 Combination of adapalene and benzoyl peroxide for treating inflammatory acne lesions

Country Status (23)

Country Link
US (6) US8129362B2 (en)
EP (2) EP2046318B1 (en)
JP (3) JP2009542779A (en)
KR (3) KR20150003917A (en)
CN (1) CN101541320B (en)
AR (1) AR061989A1 (en)
AU (1) AU2007274288B2 (en)
BR (1) BRPI0713182A8 (en)
CA (1) CA2656456A1 (en)
CO (1) CO6150136A2 (en)
CY (1) CY1121398T1 (en)
DK (2) DK2046318T3 (en)
ES (2) ES2423951T3 (en)
FR (1) FR2903603B1 (en)
HU (1) HUE043502T2 (en)
LT (1) LT2450035T (en)
MX (1) MX2009000319A (en)
PL (2) PL2450035T3 (en)
PT (2) PT2046318E (en)
RU (3) RU2009104949A (en)
SI (2) SI2450035T1 (en)
TR (1) TR201819658T4 (en)
WO (1) WO2008006888A1 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7820186B2 (en) 2001-12-21 2010-10-26 Galderma Research & Development Gel composition for once-daily treatment of common acne comprising a combination of benzoyl peroxide and adapalene and/or adapalene salt
FR2910321B1 (en) 2006-12-21 2009-07-10 Galderma Res & Dev S N C Snc CREAM GEL COMPRISING AT LEAST ONE RETINOID AND BENZOLE PEROXIDE
FR2910320B1 (en) 2006-12-21 2009-02-13 Galderma Res & Dev S N C Snc EMULSION COMPRISING AT LEAST ONE RETINOID AND BENZOLE PEROXIDE
SI2114392T1 (en) * 2007-01-30 2016-01-29 Galderma Research & Development Use of adapalene and benzoyl peroxide for the long term treatment of acne vulgaris
WO2009077693A2 (en) 2007-11-30 2009-06-25 Galderma Research & Development Compositions containing at least one naphthoic acid derivative, benzoyl peroxide and at least one film-forming agent, methods for preparing same and uses thereof
US8853275B2 (en) 2008-05-16 2014-10-07 Galderma Research & Development Concurrent therapy regime/regimen for the treatment of acne related diseases
WO2011098391A1 (en) * 2010-02-09 2011-08-18 Galderma Research & Development A dermatological composition comprising a combination of adapalene and benzoyl peroxide for the treatment of acne in non- caucasian population with decrease of post- inflammatory hyperpigmentation
EP2563357B1 (en) * 2010-04-29 2018-10-17 Galderma Research & Development Adapalene 0.3% for use in a method for treating scars
FR2969491B1 (en) * 2010-12-23 2013-07-12 Galderma Res & Dev DERMATOLOGICAL FOAMS OBTAINED FROM GEL OR SUSPENSION CONTAINING A COMBINATION OF ADAPALENE AND BPO
US8563535B2 (en) * 2011-03-29 2013-10-22 Kamal Mehta Combination composition comprising benzoyl peroxide and adapalene
CA2870690A1 (en) * 2012-05-25 2013-11-28 Galderma Research & Development Treatment of preadolescent moderate acne vulgaris
KR20150085069A (en) * 2012-11-20 2015-07-22 알레간 인코포레이티드 Topical dapsone and dapsone/adapalene compositions and methods for use thereof
WO2015150332A1 (en) * 2014-04-01 2015-10-08 Galderma Research & Development Combination of adapalene and benzoyl peroxide for treating acne scars
CN107072939A (en) 2014-07-25 2017-08-18 盖尔德马研究及发展公司 Combination of adapalene and benzoyl peroxide for the treatment of severe acne
MX2018002176A (en) * 2015-08-20 2018-06-15 Sol Gel Tech Ltd Compositions for topical application comprising benzoyl peroxide and adapalene.
JP6679299B2 (en) * 2015-12-21 2020-04-15 第一三共ヘルスケア株式会社 Topical pharmaceutical composition for treating acne
KR101986177B1 (en) * 2016-10-31 2019-06-05 (주)동구바이오제약 Pharmaceutical composition with improved bioavailability for acne treatment
WO2018080284A1 (en) * 2016-10-31 2018-05-03 (주)동구바이오제약 Pharmaceutical composition for enhancing bioavailability of drug for treatment of acne
MX2017003003A (en) * 2017-03-08 2018-09-07 Centro Int De Cosmiatria S A P I De C V Composition and method for the topical treatment of severe acne.
WO2018183763A1 (en) * 2017-03-30 2018-10-04 Zubovskiy Konstantin Method of treating and preventing infections
WO2023177625A1 (en) * 2022-03-14 2023-09-21 Blue Hill Technologies Llc Shelf-stable formulations of benzoyl peroxide and methods of producing same

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW203552B (en) * 1992-02-18 1993-04-11 J Baroody Lloyd Compositions of clindamycin and benzoyl peroxide for acne treatment
FR2727609B1 (en) 1994-12-06 1997-01-10 Oreal DISPENSING ASSEMBLY FOR THE APPLICATION OF A LIQUID CONSISTENT TO PASTE
FR2775566B1 (en) 1998-03-03 2000-05-12 Oreal GRAPE HOLDER CUP AND PACKAGING ASSEMBLY FOR A MAKEUP PRODUCT COMPRISING SAME
US6559189B2 (en) * 1999-04-28 2003-05-06 Regents Of The University Of Michigan Non-toxic antimicrobial compositions and methods of use
FR2806273B1 (en) 2000-03-16 2002-10-04 Oreal DEVICE FOR PACKAGING AND APPLYING A COSMETIC OR CARE PRODUCT
US7820186B2 (en) * 2001-12-21 2010-10-26 Galderma Research & Development Gel composition for once-daily treatment of common acne comprising a combination of benzoyl peroxide and adapalene and/or adapalene salt
FR2833841B1 (en) * 2001-12-21 2005-07-22 Galderma Res & Dev GEL COMPRISING AT LEAST ONE RETINOID AND BENZOYL PEROXIDE
FR2837101B1 (en) 2002-03-12 2004-07-02 Galderma Res & Dev USE OF 6- [1-ADAMANTYL) -4-METHOXYPHENYL] -2- NAPHTHOIC ACID FOR THE TREATMENT OF DERMATOLOGICAL DISORDERS
GB0301577D0 (en) * 2003-01-23 2003-02-26 Edko Pazarlama Tanitim Ltd Sti Topical pharmaceutical and/or cosmetic dispense systems
EP1648491A1 (en) * 2003-07-23 2006-04-26 XOMA Technology Ltd. Use of xmp-629 for the treatment of acne
US20050239723A1 (en) * 2004-04-27 2005-10-27 Amin Avinash N Compositions and methods useful for treatment of acne
US20060128808A1 (en) * 2004-10-20 2006-06-15 Galderma Research & Development, S.N.C. Method of using adapalene in acne maintenance therapy
AR054805A1 (en) * 2005-06-29 2007-07-18 Stiefel Laboratories TOPICAL COMPOSITIONS FOR SKIN TREATMENT
FR2901139B1 (en) 2006-05-17 2009-03-20 Galderma Res & Dev S N C Snc COMPOSITIONS COMPRISING AT LEAST ONE DERIVATIVE OF NAPHTHOIC ACID AND BENZOYL PEROXIDE, PROCESSES FOR THEIR PREPARATION, AND USES THEREOF

Also Published As

Publication number Publication date
HUE043502T2 (en) 2019-08-28
CY1121398T1 (en) 2020-05-29
US20120059063A1 (en) 2012-03-08
PT2046318E (en) 2013-09-04
EP2046318B1 (en) 2013-06-05
CO6150136A2 (en) 2010-04-20
US8071644B2 (en) 2011-12-06
US20090253788A1 (en) 2009-10-08
KR20160120352A (en) 2016-10-17
US20120115947A1 (en) 2012-05-10
KR20150003917A (en) 2015-01-09
RU2012144414A (en) 2014-04-27
US8129362B2 (en) 2012-03-06
TR201819658T4 (en) 2019-01-21
SI2046318T1 (en) 2013-11-29
LT2450035T (en) 2019-01-25
US20140296340A1 (en) 2014-10-02
EP2450035B1 (en) 2018-11-21
US8785420B2 (en) 2014-07-22
BRPI0713182A8 (en) 2018-01-02
US20170202803A1 (en) 2017-07-20
RU2012136952A (en) 2014-03-10
CN101541320A (en) 2009-09-23
ES2703505T3 (en) 2019-03-11
PL2450035T3 (en) 2019-04-30
JP2014040481A (en) 2014-03-06
FR2903603B1 (en) 2009-03-20
JP2016029094A (en) 2016-03-03
PT2450035T (en) 2019-02-26
EP2450035A1 (en) 2012-05-09
AR061989A1 (en) 2008-08-10
MX2009000319A (en) 2009-03-12
CA2656456A1 (en) 2008-01-17
ES2423951T3 (en) 2013-09-25
PL2046318T3 (en) 2013-12-31
RU2009104949A (en) 2010-08-20
BRPI0713182A2 (en) 2012-04-17
AU2007274288A1 (en) 2008-01-17
AU2007274288B2 (en) 2013-05-02
FR2903603A1 (en) 2008-01-18
WO2008006888A1 (en) 2008-01-17
US20080033047A1 (en) 2008-02-07
DK2450035T3 (en) 2019-02-25
JP2009542779A (en) 2009-12-03
KR20090028764A (en) 2009-03-19
EP2046318A1 (en) 2009-04-15
DK2046318T3 (en) 2013-08-05
CN101541320B (en) 2014-04-09

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