SI1827461T1 - Cladribine regimen for treating multiple sclerosis - Google Patents

Cladribine regimen for treating multiple sclerosis

Info

Publication number
SI1827461T1
SI1827461T1 SI200531514T SI200531514T SI1827461T1 SI 1827461 T1 SI1827461 T1 SI 1827461T1 SI 200531514 T SI200531514 T SI 200531514T SI 200531514 T SI200531514 T SI 200531514T SI 1827461 T1 SI1827461 T1 SI 1827461T1
Authority
SI
Slovenia
Prior art keywords
multiple sclerosis
treating multiple
cladribine
regimen
cladribine regimen
Prior art date
Application number
SI200531514T
Other languages
Slovenian (sl)
Inventor
Luca Giampiero De
Arnaud Ythier
Alain Munafo
Maria Lopez-Bresnahan
Original Assignee
Merck Serono As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Serono As filed Critical Merck Serono As
Priority claimed from PCT/EP2005/056954 external-priority patent/WO2006067141A1/en
Publication of SI1827461T1 publication Critical patent/SI1827461T1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • A61K38/215IFN-beta

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Chemical And Physical Treatments For Wood And The Like (AREA)
  • Pressure Welding/Diffusion-Bonding (AREA)

Abstract

The present invention is related to the use of Cladribine for the preparation of a pharmaceutical formulation for the treatment of multiple sclerosis, especially relapsing-remitting multiple sclerosis or early secondary progressive multiple sclerosis, wherein the preparation is to be the orally administered and wherein re-treatments are possible.
SI200531514T 2004-12-22 2005-12-20 Cladribine regimen for treating multiple sclerosis SI1827461T1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US63866904P 2004-12-22 2004-12-22
EP04106909 2004-12-22
PCT/EP2005/056954 WO2006067141A1 (en) 2004-12-22 2005-12-20 Cladribine regimen for treating multiple sclerosis
EP05823474A EP1827461B1 (en) 2004-12-22 2005-12-20 Cladribine regimen for treating multiple sclerosis

Publications (1)

Publication Number Publication Date
SI1827461T1 true SI1827461T1 (en) 2012-05-31

Family

ID=34930135

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200531514T SI1827461T1 (en) 2004-12-22 2005-12-20 Cladribine regimen for treating multiple sclerosis

Country Status (10)

Country Link
AT (1) ATE547106T1 (en)
DK (1) DK1827461T3 (en)
ES (4) ES2382554T3 (en)
HU (1) HUE035859T2 (en)
LT (1) LT2805723T (en)
ME (1) ME01333B (en)
PT (3) PT3332789T (en)
RS (1) RS52219B (en)
SI (1) SI1827461T1 (en)
UA (1) UA96260C2 (en)

Also Published As

Publication number Publication date
ES2666146T3 (en) 2018-05-03
HUE035859T2 (en) 2018-05-28
ES2495392T3 (en) 2014-09-17
ME01333B (en) 2013-12-20
PT2805723T (en) 2018-01-25
UA96260C2 (en) 2011-10-25
ATE547106T1 (en) 2012-03-15
RS52219B (en) 2012-10-31
PT1827461E (en) 2012-05-07
ES2382554T3 (en) 2012-06-11
DK1827461T3 (en) 2012-03-26
LT2805723T (en) 2018-02-12
PT3332789T (en) 2022-07-05
ES2428741T3 (en) 2013-11-11

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