SI1796664T1 - Novi tetraciklični derivati, ki vsebujejo heteroatome, in so uporabni kot modulatorji receptorja spolnega steoidnega hormona - Google Patents
Novi tetraciklični derivati, ki vsebujejo heteroatome, in so uporabni kot modulatorji receptorja spolnega steoidnega hormonaInfo
- Publication number
- SI1796664T1 SI1796664T1 SI200531817T SI200531817T SI1796664T1 SI 1796664 T1 SI1796664 T1 SI 1796664T1 SI 200531817 T SI200531817 T SI 200531817T SI 200531817 T SI200531817 T SI 200531817T SI 1796664 T1 SI1796664 T1 SI 1796664T1
- Authority
- SI
- Slovenia
- Prior art keywords
- hormone receptor
- receptor modulators
- steroid hormone
- derivatives useful
- heteroatom containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/34—Gestagens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Physical Education & Sports Medicine (AREA)
- Gynecology & Obstetrics (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Virology (AREA)
- Nutrition Science (AREA)
- Immunology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pregnancy & Childbirth (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61147604P | 2004-09-20 | 2004-09-20 | |
PCT/US2005/033330 WO2006047017A1 (en) | 2004-09-20 | 2005-09-16 | Novel tetracyclic heteroatom containing derivatives useful as sex steroid hormone receptor modulators |
EP05851212.0A EP1796664B1 (en) | 2004-09-20 | 2005-09-16 | Novel tetracyclic heteroatom containing derivatives useful as sex steroid hormone receptor modulators |
Publications (1)
Publication Number | Publication Date |
---|---|
SI1796664T1 true SI1796664T1 (sl) | 2014-02-28 |
Family
ID=35841856
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200531817T SI1796664T1 (sl) | 2004-09-20 | 2005-09-16 | Novi tetraciklični derivati, ki vsebujejo heteroatome, in so uporabni kot modulatorji receptorja spolnega steoidnega hormona |
Country Status (12)
Country | Link |
---|---|
US (2) | US7759498B2 (sl) |
EP (1) | EP1796664B1 (sl) |
JP (1) | JP5190266B2 (sl) |
CN (1) | CN101060838B (sl) |
AU (1) | AU2005300030B2 (sl) |
CA (1) | CA2581223A1 (sl) |
DK (1) | DK1796664T3 (sl) |
ES (1) | ES2446044T3 (sl) |
PL (1) | PL1796664T3 (sl) |
PT (1) | PT1796664E (sl) |
SI (1) | SI1796664T1 (sl) |
WO (1) | WO2006047017A1 (sl) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2580777A1 (en) * | 2004-09-20 | 2006-03-30 | Janssen Pharmaceutica N.V. | Novel tetracyclic heteroatom containing derivatives useful as sex steroid hormone receptor modulators |
JP2012051804A (ja) * | 2008-12-26 | 2012-03-15 | Kyoto Univ | Eg5阻害剤 |
JP6653573B2 (ja) | 2012-05-22 | 2020-02-26 | トラスティーズ・オブ・ダートマウス・カレッジ | シクロアルカニル[b]インドール、シクロアルカニル[b]ベンゾフラン、シクロアルカニル[b]ベンゾチオフェンを合成するための方法、化合物および使用の方法 |
TW201422590A (zh) * | 2012-09-07 | 2014-06-16 | Abbvie Inc | 雜環核激素受體調節劑 |
KR101561332B1 (ko) | 2012-12-10 | 2015-10-26 | 주식회사 두산 | 신규 유기 화합물 및 이를 포함하는 유기 전계 발광 소자 |
EP2935284A4 (en) | 2012-12-21 | 2016-04-27 | Abbvie Inc | HETEROCYCLIC MODULATORS OF HORMONE NUCLEAR RECEPTORS |
KR101612160B1 (ko) * | 2013-07-22 | 2016-04-12 | 주식회사 두산 | 유기 화합물 및 이를 포함하는 유기 전계 발광 소자 |
CN110818706B (zh) * | 2018-08-09 | 2020-11-24 | 苏州东南药业股份有限公司 | 一种四稠环喹喔啉类衍生物及其制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5688808A (en) | 1994-12-22 | 1997-11-18 | Ligand Pharmaceuticals Incorporated | Steroid receptor modulator compounds and methods |
NZ504667A (en) | 1997-12-04 | 2003-03-28 | Allergan Sales Inc | Substituted imidazole derivatives having agonist-like activity at alpha 2B or 2B/2C adrenergic receptors |
JPH11322756A (ja) * | 1998-03-17 | 1999-11-24 | Nippon Soda Co Ltd | ベンゾチオピラノインドール化合物および農園芸用殺菌剤 |
CN1173973C (zh) * | 1998-05-12 | 2004-11-03 | 惠氏公司 | 苯并咔唑和茚并吲哚衍生的雌激素药 |
CA2338298A1 (en) | 1998-07-29 | 2000-02-10 | Merck & Co., Inc. | Tricyclic compounds |
EP1467998B1 (en) | 2001-12-19 | 2006-03-29 | Ortho-Mcneil Pharmaceutical, Inc. | Tetracyclic heterocompounds as estrogen receptor modulators |
WO2005094833A1 (en) | 2004-03-31 | 2005-10-13 | Council Of Scientific And Industrial Research | Novel n-substituted dihydrobenzothiepino, dihydrobenzoxepino and tetrahydro benzocyclohepta indoles as selective estrogen receptor modulators |
-
2005
- 2005-09-16 SI SI200531817T patent/SI1796664T1/sl unknown
- 2005-09-16 WO PCT/US2005/033330 patent/WO2006047017A1/en active Application Filing
- 2005-09-16 AU AU2005300030A patent/AU2005300030B2/en not_active Ceased
- 2005-09-16 PL PL05851212T patent/PL1796664T3/pl unknown
- 2005-09-16 JP JP2007532548A patent/JP5190266B2/ja not_active Expired - Fee Related
- 2005-09-16 CA CA002581223A patent/CA2581223A1/en not_active Abandoned
- 2005-09-16 US US11/228,585 patent/US7759498B2/en not_active Expired - Fee Related
- 2005-09-16 CN CN2005800393419A patent/CN101060838B/zh not_active Expired - Fee Related
- 2005-09-16 PT PT58512120T patent/PT1796664E/pt unknown
- 2005-09-16 ES ES05851212.0T patent/ES2446044T3/es active Active
- 2005-09-16 DK DK05851212.0T patent/DK1796664T3/da active
- 2005-09-16 EP EP05851212.0A patent/EP1796664B1/en active Active
-
2010
- 2010-02-02 US US12/698,499 patent/US8318766B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
AU2005300030B2 (en) | 2012-01-12 |
PT1796664E (pt) | 2014-02-14 |
AU2005300030A1 (en) | 2006-05-04 |
US7759498B2 (en) | 2010-07-20 |
EP1796664A1 (en) | 2007-06-20 |
WO2006047017A1 (en) | 2006-05-04 |
PL1796664T3 (pl) | 2014-04-30 |
US20100204239A1 (en) | 2010-08-12 |
EP1796664B1 (en) | 2013-11-27 |
CN101060838B (zh) | 2012-02-29 |
CA2581223A1 (en) | 2006-05-04 |
CN101060838A (zh) | 2007-10-24 |
US20060116513A1 (en) | 2006-06-01 |
DK1796664T3 (da) | 2014-01-20 |
ES2446044T3 (es) | 2014-03-06 |
US8318766B2 (en) | 2012-11-27 |
JP2008513487A (ja) | 2008-05-01 |
JP5190266B2 (ja) | 2013-04-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PT1796664E (pt) | Novos derivados tetracíclicos contendo hetoroátomos úteis como moduladores do receptor da hormona esteroide sexual | |
IL182685A0 (en) | Novel sulphonamide derivatives as glucocorticoid receptor modulators for the treatment of inflammatory diseases | |
IL181043A0 (en) | Progesterone receptor modulators comprising pyrrole-oxindole derivatives and uses thereof | |
IL180955A0 (en) | Progesterone receptor modulators comprising pyrrole- oxindole derivatives and uses thereof | |
DE60327767D1 (de) | Tricyclische steroidhormonkernrezeptor-modulatoren | |
ZA200704223B (en) | Estrogen receptor modulators | |
EP1778242A4 (en) | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF STEROIDHORMONE NUCLEAR RECEPTORS | |
PL376803A1 (pl) | Nowe pochodne tetracykliczne zawierające heteroatomy, jako selektywne modulatory receptora estrogenowego | |
AU2003230581A1 (en) | Dihydroindol-2-one derivatives as steroid hormone nuclear receptor modulators | |
IL182829A0 (en) | Estrogen receptor modulators | |
ZA200609234B (en) | Substituted azeplne derivatives as serotonin receptor modulators | |
IL180977A0 (en) | Tricyclic indeno-pyrrole derivatives as serotonin receptor modulators | |
IL175996A0 (en) | Tricyclic steroid hormone nuclear receptor modulators | |
ZA200703389B (en) | Novel sulphonamide derivatives as glucocorticoid receptor modulators for the treatment of inflammatory diseases | |
HK1131396A1 (en) | 11-phosphorous steroid derivatives useful as progesterone receptor modulators | |
IL180637A0 (en) | Tricyclic pyrazole derivatives as cannabinoid receptor modulators | |
IL188022A0 (en) | Benzofuranone derivatives as nonsteroidal progesterone receptor modulators | |
PL2064238T3 (pl) | Struktura krystaliczna receptora hormonu tyreotropowego | |
HK1144287A1 (en) | Steroids derivatives as selective progesterone receptor modulators | |
EP1641464A4 (en) | 17-ACETAMIDO-4-AZASTEROID DERIVATIVES AS MODULATORS OF THE ANDROGEN RECEPTOR | |
ZA200703201B (en) | Novel sulphonamide derivatives as glucocorticoid receptor modulators for the treatment of inflammatory diseases | |
HK1096405A1 (en) | Progesterone receptor modulators | |
HK1131787A1 (en) | Oxa-steroids derivatives as selective progesterone receptor modulators | |
ZA200907546B (en) | New progesterone receptor modulators | |
ZA200701157B (en) | Progesterone receptor modulators comprising pyrroleoxindole derivatives and uses thereof |