SI1592457T1 - Folate-vinblastine conjugate as medicament - Google Patents

Folate-vinblastine conjugate as medicament

Info

Publication number
SI1592457T1
SI1592457T1 SI200431940T SI200431940T SI1592457T1 SI 1592457 T1 SI1592457 T1 SI 1592457T1 SI 200431940 T SI200431940 T SI 200431940T SI 200431940 T SI200431940 T SI 200431940T SI 1592457 T1 SI1592457 T1 SI 1592457T1
Authority
SI
Slovenia
Prior art keywords
folate
medicament
vinblastine conjugate
vinblastine
conjugate
Prior art date
Application number
SI200431940T
Other languages
Slovenian (sl)
Inventor
Iontcho Radoslavov Vlahov
Christopher Paul Leamon
Matthew A. Parker
Stephen J. Howard
Hari Krishna Santhapuram
Apparao Satyam
Joseph Anand Reddy
Original Assignee
Endocyte, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Endocyte, Inc. filed Critical Endocyte, Inc.
Priority claimed from PCT/US2004/002070 external-priority patent/WO2004069159A2/en
Publication of SI1592457T1 publication Critical patent/SI1592457T1/en

Links

SI200431940T 2003-01-27 2004-01-27 Folate-vinblastine conjugate as medicament SI1592457T1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US44284503P 2003-01-27 2003-01-27
US49211903P 2003-08-01 2003-08-01
US51618803P 2003-10-31 2003-10-31
PCT/US2004/002070 WO2004069159A2 (en) 2003-01-27 2004-01-27 Vitamin receptor binding drug delivery conjugates
EP04705573A EP1592457B1 (en) 2003-01-27 2004-01-27 Folate-vinblastine conjugate as medicament

Publications (1)

Publication Number Publication Date
SI1592457T1 true SI1592457T1 (en) 2012-12-31

Family

ID=36707301

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200431940T SI1592457T1 (en) 2003-01-27 2004-01-27 Folate-vinblastine conjugate as medicament

Country Status (3)

Country Link
CN (2) CN101239190B (en)
SI (1) SI1592457T1 (en)
ZA (1) ZA200506672B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3569251A1 (en) * 2007-06-25 2019-11-20 Endocyte, Inc. Conjugates containing hydrophilic spacer linkers
CN101701061B (en) * 2009-10-30 2011-09-28 北京化工大学 Drug delivering material taking Vitamin C as hydrophilic fragments and preparation method thereof
WO2011146707A1 (en) * 2010-05-19 2011-11-24 Endocyte, Inc. Improved process for a folate-targeted agent
CA2817223A1 (en) * 2010-11-12 2012-05-18 Endocyte, Inc. Methods of treating cancer
KR20220051197A (en) * 2012-05-17 2022-04-26 익스텐드 바이오사이언시즈, 인크. Carriers for improved drug delivery
WO2014101134A1 (en) * 2012-12-28 2014-07-03 Yan Wenguang Folic acid derivative, and preparing method and application thereof
BR112016010927A2 (en) * 2013-11-14 2017-08-08 Endocyte Inc FORMULA CONJUGATE
CN109316605B (en) * 2014-01-20 2023-07-14 博瑞生物医药（苏州）股份有限公司 Folate receptor binding ligand-drug conjugates
CN103861116A (en) * 2014-03-06 2014-06-18 沈阳药大制剂新技术有限公司 Prodrug of antitumor medicament as well as preparation method and application thereof
EP3220961B1 (en) 2014-10-22 2023-07-05 Extend Biosciences, Inc. Therapeutic vitamin d conjugates
US9616109B2 (en) 2014-10-22 2017-04-11 Extend Biosciences, Inc. Insulin vitamin D conjugates
CN105801604B (en) * 2016-03-07 2017-12-22 孙关 Eriocalyxin B derivates thing, Preparation method and use with tumor-targeting
CN115505029A (en) * 2017-12-13 2022-12-23 杭州多禧生物科技有限公司 Cytotoxin molecule, conjugate, preparation method and application thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5688488A (en) * 1989-04-03 1997-11-18 Purdue Research Foundation Composition and method for tumor imaging
US5837533A (en) * 1994-09-28 1998-11-17 American Home Products Corporation Complexes comprising a nucleic acid bound to a cationic polyamine having an endosome disruption agent
GB9600272D0 (en) * 1996-01-06 1996-03-06 Univ Nottingham Polymers
AUPQ071299A0 (en) * 1999-06-02 1999-06-24 Access Pharmaceuticals Australia Pty Limited Vitamin directed dual targeting therapy
DK1286704T3 (en) * 2000-06-02 2014-09-22 Univ Texas Ethylenedicine (EC) -glucose analog conjugates
CN1635910A (en) * 2001-05-02 2005-07-06 普渡研究基金会 Treatment and diagnosis of macrophage mediated disease
ES2324708T3 (en) * 2002-05-15 2009-08-13 Endocyte, Inc. VITAMIN-MYTHOMYCIN CONJUGATES.

Also Published As

Publication number Publication date
CN1761488A (en) 2006-04-19
ZA200506672B (en) 2010-08-25
CN100381177C (en) 2008-04-16
CN101239190A (en) 2008-08-13
CN101239190B (en) 2013-09-25

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