SI1187805T1 - Postopek za pripravo r-(-)-karnitina iz s-(-)-klorojantarne kisline ali njenega derivata - Google Patents

Postopek za pripravo r-(-)-karnitina iz s-(-)-klorojantarne kisline ali njenega derivata

Info

Publication number
SI1187805T1
SI1187805T1 SI200030921T SI200030921T SI1187805T1 SI 1187805 T1 SI1187805 T1 SI 1187805T1 SI 200030921 T SI200030921 T SI 200030921T SI 200030921 T SI200030921 T SI 200030921T SI 1187805 T1 SI1187805 T1 SI 1187805T1
Authority
SI
Slovenia
Prior art keywords
carnitine
derivative
preparing
chlorosuccinic acid
chlorosuccinic
Prior art date
Application number
SI200030921T
Other languages
English (en)
Inventor
Piero Melloni
Alberto Cerri
Marco Santagostino
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT1999RM000310 external-priority patent/IT1306142B1/it
Priority claimed from IT1999RM000670 external-priority patent/IT1306737B1/it
Priority claimed from IT2000RM000061 external-priority patent/IT1316989B1/it
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Priority claimed from EP00927737A external-priority patent/EP1187805B1/en
Publication of SI1187805T1 publication Critical patent/SI1187805T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63—Esters of sulfonic acids
    • C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
    • C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • C07C309/66—Methanesulfonates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04—Formation of amino groups in compounds containing carboxyl groups
    • C07C227/06—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid
    • C07C227/08—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid by reaction of ammonia or amines with acids containing functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30—Preparation of optical isomers
    • C07C227/32—Preparation of optical isomers by stereospecific synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/48—Separation; Purification; Stabilisation; Use of additives by liquid-liquid treatment
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/54—Preparation of carboxylic acid anhydrides
    • C07C51/56—Preparation of carboxylic acid anhydrides from organic acids, their salts, their esters or their halides, e.g. by carboxylation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/62—Halogen-containing esters
    • C07C69/63—Halogen-containing esters of saturated acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
SI200030921T 1999-05-18 2000-05-12 Postopek za pripravo r-(-)-karnitina iz s-(-)-klorojantarne kisline ali njenega derivata SI1187805T1 (sl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IT1999RM000310 IT1306142B1 (it) 1999-05-18 1999-05-18 Procedimento per la preparazione di r-(-)-carnitina a partiredall'acido s-(-)-clorosuccinico.
IT1999RM000670 IT1306737B1 (it) 1999-10-29 1999-10-29 Procedimento per la preparazione di acidi carbossilici chirali.
IT2000RM000061 IT1316989B1 (it) 2000-02-10 2000-02-10 Procedimento per la preparazione di r-(-)- carnitina a partire daacido s-(-)- clorosuccinico o da un suo derivato.
EP00927737A EP1187805B1 (en) 1999-05-18 2000-05-12 Process for preparing r-(-)-carnitine from s-(-)-chlorosuccinic acid or from a derivative thereof
PCT/IT2000/000187 WO2000069808A1 (en) 1999-05-18 2000-05-12 Process for preparing r-(-)-carnitine from s-(-)-chlorosuccinic acid or from a derivative thereof

Publications (1)

Publication Number Publication Date
SI1187805T1 true SI1187805T1 (sl) 2007-04-30

Family

ID=32913086

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200030921T SI1187805T1 (sl) 1999-05-18 2000-05-12 Postopek za pripravo r-(-)-karnitina iz s-(-)-klorojantarne kisline ali njenega derivata

Country Status (1)

Country Link
SI (1) SI1187805T1 (sl)

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