SI1185274T1 - Drug combinations comprising (e)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(methyl(methylsulfonyl)amino)pyrimidin-5-yl)(3r,5s)-3,5-dihydroxyhept-6-enoic acid and an inhibitor, inducer or substrate of p450 isoenzyme 3a4 - Google Patents

Drug combinations comprising (e)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(methyl(methylsulfonyl)amino)pyrimidin-5-yl)(3r,5s)-3,5-dihydroxyhept-6-enoic acid and an inhibitor, inducer or substrate of p450 isoenzyme 3a4

Info

Publication number
SI1185274T1
SI1185274T1 SI200030590T SI200030590T SI1185274T1 SI 1185274 T1 SI1185274 T1 SI 1185274T1 SI 200030590 T SI200030590 T SI 200030590T SI 200030590 T SI200030590 T SI 200030590T SI 1185274 T1 SI1185274 T1 SI 1185274T1
Authority
SI
Slovenia
Prior art keywords
dihydroxyhept
isoenzyme
inducer
methylsulfonyl
pyrimidin
Prior art date
Application number
SI200030590T
Other languages
Slovenian (sl)
Inventor
Ali Raza
John Stuart Pears
Howard Gerard Hutchinson
Dennis Schneck
Takahiko Baba
Akira Touchi
Yoshitaka Yamaguchi
Original Assignee
Astrazeneca Ab
Shionogi & Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9902593.4A external-priority patent/GB9902593D0/en
Priority claimed from GBGB9921064.3A external-priority patent/GB9921064D0/en
Priority claimed from GBGB9921063.5A external-priority patent/GB9921063D0/en
Application filed by Astrazeneca Ab, Shionogi & Co., Ltd. filed Critical Astrazeneca Ab
Priority claimed from PCT/GB2000/000278 external-priority patent/WO2000045817A1/en
Publication of SI1185274T1 publication Critical patent/SI1185274T1/en

Links

SI200030590T 1999-02-06 2000-02-01 Drug combinations comprising (e)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(methyl(methylsulfonyl)amino)pyrimidin-5-yl)(3r,5s)-3,5-dihydroxyhept-6-enoic acid and an inhibitor, inducer or substrate of p450 isoenzyme 3a4 SI1185274T1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB9902593.4A GB9902593D0 (en) 1999-02-06 1999-02-06 Drug combinations
GBGB9921064.3A GB9921064D0 (en) 1999-09-08 1999-09-08 Drug combination
GBGB9921063.5A GB9921063D0 (en) 1999-09-08 1999-09-08 Therapy
PCT/GB2000/000278 WO2000045817A1 (en) 1999-02-06 2000-02-01 Drug combinations comprising (e) -7 - [4 -(4 -fluorophenyl) -6 - isopropyl -2 - [methyl (methylsulfonyl) amino] pyrimidin -5 -yl] (3r,5s) -3,5 - dihydroxyhept -6 - enoic acid and an inhibitor, inducer or substrate of p450 isoenzyme 3a4
EP00901264A EP1185274B1 (en) 1999-02-06 2000-02-01 Drug combinations comprising (e)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3r,5s)-3,5-dihydroxyhept-6-enoic acid and an inhibitor, inducer or substrate of p450 isoenzyme 3a4

Publications (1)

Publication Number Publication Date
SI1185274T1 true SI1185274T1 (en) 2005-06-30

Family

ID=34753753

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200030590T SI1185274T1 (en) 1999-02-06 2000-02-01 Drug combinations comprising (e)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(methyl(methylsulfonyl)amino)pyrimidin-5-yl)(3r,5s)-3,5-dihydroxyhept-6-enoic acid and an inhibitor, inducer or substrate of p450 isoenzyme 3a4

Country Status (1)

Country Link
SI (1) SI1185274T1 (en)

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