SI1114166T1 - Method for down-regulating osteoprotegerin ligand activity - Google Patents
Method for down-regulating osteoprotegerin ligand activityInfo
- Publication number
- SI1114166T1 SI1114166T1 SI9930789T SI9930789T SI1114166T1 SI 1114166 T1 SI1114166 T1 SI 1114166T1 SI 9930789 T SI9930789 T SI 9930789T SI 9930789 T SI9930789 T SI 9930789T SI 1114166 T1 SI1114166 T1 SI 1114166T1
- Authority
- SI
- Slovenia
- Prior art keywords
- ligand activity
- osteoprotegerin ligand
- regulating
- regulating osteoprotegerin
- activity
- Prior art date
Links
- 102000014128 RANK Ligand Human genes 0.000 title 1
- 108010025832 RANK Ligand Proteins 0.000 title 1
- 230000002222 downregulating effect Effects 0.000 title 1
- 230000000694 effects Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55544—Bacterial toxins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA199801164 | 1998-09-15 | ||
US10289698P | 1998-10-02 | 1998-10-02 | |
PCT/DK1999/000481 WO2000015807A1 (fr) | 1998-09-15 | 1999-09-13 | Procede de regulation negative de l'activite des ligands d'osteoprotegerine |
EP99942778A EP1114166B1 (fr) | 1998-09-15 | 1999-09-13 | Procede de regulation negative de l'activite des ligands d'osteoprotegerine |
Publications (1)
Publication Number | Publication Date |
---|---|
SI1114166T1 true SI1114166T1 (en) | 2005-10-31 |
Family
ID=34527328
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI9930789T SI1114166T1 (en) | 1998-09-15 | 1999-09-13 | Method for down-regulating osteoprotegerin ligand activity |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP1541587A3 (fr) |
DK (1) | DK1114166T3 (fr) |
SI (1) | SI1114166T1 (fr) |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1237764B (it) * | 1989-11-10 | 1993-06-17 | Eniricerche Spa | Peptidi sintetici utili come carriers universali per la preparazione di coniugati immunogenici e loro impiego per lo sviluppo di vaccini sintetici. |
DK96493D0 (da) * | 1993-08-26 | 1993-08-26 | Mouritsen Og Elsner Aps | Fremgangsmaade til at inducere antistofresponser mod selvproteiner og autovaccine fremstillet ved fremgangsmaaden |
EP1114864B9 (fr) * | 1996-12-13 | 2013-05-08 | Schering Corporation | Antigènes de surface de cellules de mammifères |
EP2371962A3 (fr) * | 1996-12-23 | 2011-12-21 | Immunex Corporation | Activateur du récepteur de NF-KAPPA B, récepteur membre de la superfamille des récepteurs de TNF |
RO128635A2 (ro) * | 1997-04-16 | 2013-07-30 | Amgen Inc. | Anticorp sau fragment al acestuia care se leagă la opgbp şi utilizarea acestuia, utilizarea unei forme solubile de odar, şi metodă de identificare a unui compus care descreşte activitatea opgbp |
-
1999
- 1999-09-13 DK DK99942778T patent/DK1114166T3/da active
- 1999-09-13 EP EP05005544A patent/EP1541587A3/fr not_active Withdrawn
- 1999-09-13 SI SI9930789T patent/SI1114166T1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
EP1541587A3 (fr) | 2007-06-20 |
DK1114166T3 (da) | 2005-08-01 |
EP1541587A2 (fr) | 2005-06-15 |
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