SG120094A1 - Process for the enzymatic preparation of enantiomerically enriched beta-amino acids - Google Patents
Process for the enzymatic preparation of enantiomerically enriched beta-amino acidsInfo
- Publication number
- SG120094A1 SG120094A1 SG200302193A SG200302193A SG120094A1 SG 120094 A1 SG120094 A1 SG 120094A1 SG 200302193 A SG200302193 A SG 200302193A SG 200302193 A SG200302193 A SG 200302193A SG 120094 A1 SG120094 A1 SG 120094A1
- Authority
- SG
- Singapore
- Prior art keywords
- amino acids
- alkyl
- enantiomerically enriched
- beta
- optionally substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Production of enantiomerically enriched, N-unprotected beta-amino acids (I) comprises enzymatic hydrolysis of an enantiomeric mixture of N-unprotected beta-aminoacid esters (II) using a hydrolase, provided that (II) is other than a methyl or ethyl ester. An Independent claim is also included for new beta-aminoacid n-propyl esters of formula (II'). R = 1-8C alkyl, 2-8C alkenyl, 2-8C alkynyl, 3-8C cycloalkyl (optionally substituted by 1-3 1-8C alkyl), 6-18C aryl (optionally substituted by 1-3 1-8C alkyl), 7-19C aralkyl, 3-18C heteroaryl (optionally substituted by 1-3 1-8C alkyl) or 4-19C heteroaralkyl; and R' = H or as defined for R.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10220739A DE10220739A1 (en) | 2002-05-08 | 2002-05-08 | Process for the enzymatic preparation of enantiomerically enriched β-amino acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG120094A1 true SG120094A1 (en) | 2006-03-28 |
Family
ID=29225124
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG200302193A SG120094A1 (en) | 2002-05-08 | 2003-04-14 | Process for the enzymatic preparation of enantiomerically enriched beta-amino acids |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP1361279B1 (en) |
| JP (1) | JP4386670B2 (en) |
| KR (1) | KR101172905B1 (en) |
| CN (1) | CN1260364C (en) |
| AT (1) | ATE332391T1 (en) |
| CA (1) | CA2428059C (en) |
| DE (3) | DE10220739A1 (en) |
| DK (1) | DK1361279T3 (en) |
| ES (1) | ES2268212T3 (en) |
| HR (1) | HRP20030357A2 (en) |
| IL (1) | IL155785A0 (en) |
| PT (1) | PT1361279E (en) |
| SG (1) | SG120094A1 (en) |
| SI (1) | SI1361279T1 (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4270991B2 (en) | 2002-10-11 | 2009-06-03 | 株式会社リコー | Information recording apparatus, information recording method, information recording program, storage medium storing information recording program, and information recording system |
| JP4591347B2 (en) * | 2003-03-17 | 2010-12-01 | 宇部興産株式会社 | 3-Amino-3-arylpropionic acid n-alkyl ester and process for producing the same, and optically active 3-amino-3-arylpropionic acid and process for producing enantiomers thereof |
| FR2853327B1 (en) * | 2003-04-04 | 2012-07-27 | Solvay | PROCESS FOR THE PRODUCTION OF ENANTIOPOR BETA-AMINOACID DERIVATIVES AND ENANTIOPA BETA-AMINOACIDIC DERIVATIVES |
| JP4361094B2 (en) | 2003-12-10 | 2009-11-11 | エボニック デグサ ゲーエムベーハー | Method for producing enantiomerically enriched amino acids |
| WO2005095325A1 (en) * | 2004-03-03 | 2005-10-13 | Degussa Ag | PROCESS FOR THE PREPARATION OF β-AMINOCARBOXYLIC ACIDS |
| WO2006038698A1 (en) * | 2004-10-08 | 2006-04-13 | Ube Industries, Ltd. | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE (S)- OR (R)-β-AMINO ACIDS AND OPTICALLY ACTIVE (R)- OR (S)-β-AMINO ACID ESTERS, 2-ALKOXYETHYL ESTERS OF β-AMINO ACIDS, AND OPTICALLY ACITVE (S)- OR (R)-2-ALKOXYETHYL ESTERS OF β-AMINO ACIDS |
| CN101180402A (en) * | 2005-05-17 | 2008-05-14 | 宇部兴产株式会社 | Process for production of carboxylic acid using surfactant-modifying enzyme |
| SG11201403306RA (en) * | 2011-12-19 | 2014-12-30 | Sumitomo Chemical Co | METHOD FOR PRODUCING OPTICALLY-ACTIVE α-SUBSTITUTED-β-AMINO ACID |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4439524A (en) * | 1979-07-07 | 1984-03-27 | Bayer Aktiengesellschaft | Stereoselective resolution of phenylglycine derivatives with enzyme resins |
| US4636470A (en) * | 1984-08-17 | 1987-01-13 | Stauffer Chemical Company | Resolution of racemates of amino acids |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5552317A (en) * | 1995-05-26 | 1996-09-03 | Industrial Technology Research Institute | Method for preparing optically active homophenylalanine and esters thereof using lipase from wheat germ or Candida lipolytica |
| CA2384191A1 (en) * | 1999-08-31 | 2001-03-08 | Benjamin M. Skead | Enantiomerically-enriched compounds having photocleavable bond(s) and methods related thereto |
-
2002
- 2002-05-08 DE DE10220739A patent/DE10220739A1/en not_active Withdrawn
-
2003
- 2003-04-14 SG SG200302193A patent/SG120094A1/en unknown
- 2003-05-06 HR HR20030357A patent/HRP20030357A2/en not_active Application Discontinuation
- 2003-05-06 IL IL15578503A patent/IL155785A0/en not_active IP Right Cessation
- 2003-05-07 ES ES03010224T patent/ES2268212T3/en not_active Expired - Lifetime
- 2003-05-07 DK DK03010224T patent/DK1361279T3/en active
- 2003-05-07 CN CNB031234275A patent/CN1260364C/en not_active Expired - Fee Related
- 2003-05-07 SI SI200330469T patent/SI1361279T1/en unknown
- 2003-05-07 DE DE50304116T patent/DE50304116D1/en not_active Expired - Lifetime
- 2003-05-07 AT AT03010224T patent/ATE332391T1/en active
- 2003-05-07 PT PT03010224T patent/PT1361279E/en unknown
- 2003-05-07 DE DE10320211A patent/DE10320211A1/en not_active Withdrawn
- 2003-05-07 CA CA2428059A patent/CA2428059C/en not_active Expired - Fee Related
- 2003-05-07 KR KR1020030028937A patent/KR101172905B1/en not_active IP Right Cessation
- 2003-05-07 EP EP03010224A patent/EP1361279B1/en not_active Expired - Lifetime
- 2003-05-08 JP JP2003130566A patent/JP4386670B2/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4439524A (en) * | 1979-07-07 | 1984-03-27 | Bayer Aktiengesellschaft | Stereoselective resolution of phenylglycine derivatives with enzyme resins |
| US4636470A (en) * | 1984-08-17 | 1987-01-13 | Stauffer Chemical Company | Resolution of racemates of amino acids |
Non-Patent Citations (1)
| Title |
|---|
| TETRAHEDRON LETTERS. VOL. 41, 2000, PAGES 2697-2681 * |
Also Published As
| Publication number | Publication date |
|---|---|
| IL155785A0 (en) | 2003-12-23 |
| PT1361279E (en) | 2006-11-30 |
| SI1361279T1 (en) | 2006-12-31 |
| DE10320211A1 (en) | 2004-02-12 |
| DE50304116D1 (en) | 2006-08-17 |
| ES2268212T3 (en) | 2007-03-16 |
| KR20030087565A (en) | 2003-11-14 |
| DE10220739A1 (en) | 2003-11-27 |
| ATE332391T1 (en) | 2006-07-15 |
| CN1456675A (en) | 2003-11-19 |
| JP2003325195A (en) | 2003-11-18 |
| EP1361279A1 (en) | 2003-11-12 |
| CA2428059C (en) | 2011-08-02 |
| CA2428059A1 (en) | 2003-11-08 |
| HRP20030357A2 (en) | 2004-04-30 |
| KR101172905B1 (en) | 2012-08-10 |
| JP4386670B2 (en) | 2009-12-16 |
| DK1361279T3 (en) | 2006-11-06 |
| CN1260364C (en) | 2006-06-21 |
| EP1361279B1 (en) | 2006-07-05 |
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