SG11202113009PA - Preparation of preliposomal annamycin lyophilizate - Google Patents

Preparation of preliposomal annamycin lyophilizate

Info

Publication number
SG11202113009PA
SG11202113009PA SG11202113009PA SG11202113009PA SG11202113009PA SG 11202113009P A SG11202113009P A SG 11202113009PA SG 11202113009P A SG11202113009P A SG 11202113009PA SG 11202113009P A SG11202113009P A SG 11202113009PA SG 11202113009P A SG11202113009P A SG 11202113009PA
Authority
SG
Singapore
Prior art keywords
preliposomal
annamycin
lyophilizate
preparation
preliposomal annamycin
Prior art date
Application number
SG11202113009PA
Inventor
Donald Picker
Waldemar Priebe
Original Assignee
Univ Texas
Moleculin Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Texas, Moleculin Llc filed Critical Univ Texas
Publication of SG11202113009PA publication Critical patent/SG11202113009PA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1277Processes for preparing; Proliposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
SG11202113009PA 2019-06-28 2020-06-25 Preparation of preliposomal annamycin lyophilizate SG11202113009PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962868184P 2019-06-28 2019-06-28
PCT/US2020/039620 WO2020264160A1 (en) 2019-06-28 2020-06-25 Preparation of preliposomal annamycin lyophilizate

Publications (1)

Publication Number Publication Date
SG11202113009PA true SG11202113009PA (en) 2021-12-30

Family

ID=74061071

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202113009PA SG11202113009PA (en) 2019-06-28 2020-06-25 Preparation of preliposomal annamycin lyophilizate

Country Status (14)

Country Link
US (2) US20220105115A1 (en)
EP (1) EP3989978A4 (en)
JP (1) JP2022538865A (en)
KR (1) KR20220027969A (en)
CN (1) CN114641296A (en)
AU (1) AU2020303572A1 (en)
BR (1) BR112021026506A2 (en)
CA (1) CA3142510A1 (en)
EA (1) EA202193193A1 (en)
IL (1) IL289432A (en)
MX (1) MX2021015668A (en)
SG (1) SG11202113009PA (en)
TW (1) TW202114703A (en)
WO (1) WO2020264160A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11202113005SA (en) 2019-06-28 2021-12-30 Univ Texas Method of reconstituting liposomal annamycin
AU2020303572A1 (en) 2019-06-28 2022-01-20 Board Of Regents, The University Of Texas System Preparation of preliposomal Annamycin lyophilizate

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5902604A (en) * 1995-06-06 1999-05-11 Board Of Regents, The University Of Texas System Submicron liposome suspensions obtained from preliposome lyophilizates
WO2001032145A1 (en) * 1999-10-29 2001-05-10 Board Of Regents, The University Of Texas System Method of cancer treatment
ES2376875T3 (en) 2003-02-14 2012-03-20 Children's Hospital & Research Center At Oakland Vehicle for administration of lipophilic drugs and methods of use thereof
AU2012322797B2 (en) 2011-10-14 2016-04-21 Genentech, Inc. Uses for and article of manufacture including HER2 dimerization inhibitor Pertuzumab
US8926994B2 (en) * 2011-12-07 2015-01-06 The Methodist Hospital Research Institute Mesoporous silicon particles for the presentation of tumor antigens and adjuvant for anti-cancer immunity
SG11202113005SA (en) 2019-06-28 2021-12-30 Univ Texas Method of reconstituting liposomal annamycin
AU2020303572A1 (en) 2019-06-28 2022-01-20 Board Of Regents, The University Of Texas System Preparation of preliposomal Annamycin lyophilizate

Also Published As

Publication number Publication date
EP3989978A4 (en) 2023-05-10
CA3142510A1 (en) 2020-12-30
US20220105115A1 (en) 2022-04-07
TW202114703A (en) 2021-04-16
CN114641296A (en) 2022-06-17
JP2022538865A (en) 2022-09-06
KR20220027969A (en) 2022-03-08
WO2020264160A1 (en) 2020-12-30
EP3989978A1 (en) 2022-05-04
IL289432A (en) 2022-02-01
EA202193193A1 (en) 2022-03-30
MX2021015668A (en) 2022-04-18
BR112021026506A2 (en) 2022-02-15
US20240041909A1 (en) 2024-02-08
US11951118B2 (en) 2024-04-09
AU2020303572A1 (en) 2022-01-20

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