SG11202112927UA - Designed ankyrin repeat domain with improved stability - Google Patents
Designed ankyrin repeat domain with improved stabilityInfo
- Publication number
- SG11202112927UA SG11202112927UA SG11202112927UA SG11202112927UA SG11202112927UA SG 11202112927U A SG11202112927U A SG 11202112927UA SG 11202112927U A SG11202112927U A SG 11202112927UA SG 11202112927U A SG11202112927U A SG 11202112927UA SG 11202112927U A SG11202112927U A SG 11202112927UA
- Authority
- SG
- Singapore
- Prior art keywords
- improved stability
- repeat domain
- ankyrin repeat
- designed ankyrin
- designed
- Prior art date
Links
- 102000008102 Ankyrins Human genes 0.000 title 1
- 108010049777 Ankyrins Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/765—Serum albumin, e.g. HSA
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/35—Fusion polypeptide containing a fusion for enhanced stability/folding during expression, e.g. fusions with chaperones or thioredoxin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19178282 | 2019-06-04 | ||
| PCT/EP2020/065314 WO2020245171A1 (en) | 2019-06-04 | 2020-06-03 | Designed ankyrin repeat domain with improved stability |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202112927UA true SG11202112927UA (en) | 2021-12-30 |
Family
ID=66826818
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202112927UA SG11202112927UA (en) | 2019-06-04 | 2020-06-03 | Designed ankyrin repeat domain with improved stability |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20240124535A1 (en) |
| EP (1) | EP3980444A1 (en) |
| JP (1) | JP2022535106A (en) |
| KR (1) | KR20220016944A (en) |
| CN (1) | CN114206908A (en) |
| AU (1) | AU2020289383A1 (en) |
| BR (1) | BR112021024237A2 (en) |
| CA (1) | CA3138805A1 (en) |
| IL (1) | IL288611A (en) |
| MX (1) | MX2021014649A (en) |
| SG (1) | SG11202112927UA (en) |
| WO (1) | WO2020245171A1 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021116462A1 (en) | 2019-12-11 | 2021-06-17 | Molecular Partners Ag | Designed ankyrin repeat domains with altered surface residues |
| AU2021267411A1 (en) | 2020-05-06 | 2022-12-08 | Molecular Partners Ag | Novel ankyrin repeat binding proteins and their uses |
| BR112023018293A2 (en) | 2021-03-09 | 2023-10-31 | Molecular Partners Ag | DARPIN-BASED MULTI-SPECIFIC T-CELL COUPLER |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1332209B1 (en) | 2000-09-08 | 2009-11-11 | Universität Zürich | Collections of repeat proteins comprising repeat modules |
| US9365629B2 (en) | 2007-09-24 | 2016-06-14 | University Of Zurich | Designed armadillo repeat proteins |
| KR20140032356A (en) | 2010-11-26 | 2014-03-14 | 몰리큘라 파트너스 아게 | Improved n-terminal capping modules for designed ankyrin repeat protein |
| EP2738180A1 (en) * | 2012-11-30 | 2014-06-04 | Molecular Partners AG | Binding proteins comprising at least two binding domains against HER2. |
| IL276944B (en) | 2015-04-02 | 2022-07-01 | Molecular Partners Ag | Designed ankyrin repeat domains with binding specificity for serum albumin |
| CN109790206A (en) | 2016-09-22 | 2019-05-21 | 分子组合公司 | Recombinant binding protein and application thereof |
-
2020
- 2020-06-03 US US17/596,102 patent/US20240124535A1/en active Pending
- 2020-06-03 CA CA3138805A patent/CA3138805A1/en active Pending
- 2020-06-03 SG SG11202112927UA patent/SG11202112927UA/en unknown
- 2020-06-03 JP JP2021571939A patent/JP2022535106A/en active Pending
- 2020-06-03 MX MX2021014649A patent/MX2021014649A/en unknown
- 2020-06-03 WO PCT/EP2020/065314 patent/WO2020245171A1/en unknown
- 2020-06-03 BR BR112021024237A patent/BR112021024237A2/en unknown
- 2020-06-03 KR KR1020227000007A patent/KR20220016944A/en active Search and Examination
- 2020-06-03 CN CN202080055757.4A patent/CN114206908A/en active Pending
- 2020-06-03 EP EP20728794.7A patent/EP3980444A1/en active Pending
- 2020-06-03 AU AU2020289383A patent/AU2020289383A1/en active Pending
-
2021
- 2021-12-02 IL IL288611A patent/IL288611A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR112021024237A2 (en) | 2022-04-19 |
| KR20220016944A (en) | 2022-02-10 |
| MX2021014649A (en) | 2022-01-06 |
| WO2020245171A1 (en) | 2020-12-10 |
| AU2020289383A1 (en) | 2021-12-23 |
| CA3138805A1 (en) | 2020-12-10 |
| IL288611A (en) | 2022-02-01 |
| US20240124535A1 (en) | 2024-04-18 |
| JP2022535106A (en) | 2022-08-04 |
| CN114206908A (en) | 2022-03-18 |
| EP3980444A1 (en) | 2022-04-13 |
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