SG11202112846RA - Methods for purifying antibodies - Google Patents

Methods for purifying antibodies

Info

Publication number
SG11202112846RA
SG11202112846RA SG11202112846RA SG11202112846RA SG11202112846RA SG 11202112846R A SG11202112846R A SG 11202112846RA SG 11202112846R A SG11202112846R A SG 11202112846RA SG 11202112846R A SG11202112846R A SG 11202112846RA SG 11202112846R A SG11202112846R A SG 11202112846RA
Authority
SG
Singapore
Prior art keywords
methods
purifying antibodies
antibodies
purifying
Prior art date
Application number
SG11202112846RA
Inventor
Neil Alan Watson
Curtis William Phippen
Original Assignee
UCB Biopharma SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UCB Biopharma SRL filed Critical UCB Biopharma SRL
Publication of SG11202112846RA publication Critical patent/SG11202112846RA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804Affinity chromatography
    • B01D15/3809Affinity chromatography of the antigen-antibody type, e.g. protein A, G, L chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/18Ion-exchange chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/22Affinity chromatography or related techniques based upon selective absorption processes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065Purification, fragmentation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/26Conditioning of the fluid carrier; Flow patterns
    • G01N30/38Flow patterns
    • G01N2030/381Flow patterns centrifugal chromatography
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/88Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8813Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
    • G01N2030/8831Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials involving peptides or proteins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SG11202112846RA 2019-08-02 2020-07-30 Methods for purifying antibodies SG11202112846RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP19189841 2019-08-02
PCT/EP2020/071533 WO2021023619A1 (en) 2019-08-02 2020-07-30 Methods for purifying antibodies

Publications (1)

Publication Number Publication Date
SG11202112846RA true SG11202112846RA (en) 2021-12-30

Family

ID=67658409

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202112846RA SG11202112846RA (en) 2019-08-02 2020-07-30 Methods for purifying antibodies

Country Status (13)

Country Link
US (1) US20220280887A1 (en)
EP (1) EP4007771A1 (en)
JP (1) JP2022543187A (en)
KR (1) KR20220039744A (en)
CN (1) CN114401984A (en)
AR (1) AR119546A1 (en)
AU (1) AU2020326087A1 (en)
BR (1) BR112021023542A2 (en)
CA (1) CA3142610A1 (en)
IL (1) IL289959A (en)
MX (1) MX2022001349A (en)
SG (1) SG11202112846RA (en)
WO (1) WO2021023619A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI787710B (en) * 2020-01-20 2022-12-21 中國大陸商上海藥明生物技術有限公司 A novel wash buffer solution for affinity chromatography

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5726293A (en) * 1992-10-02 1998-03-10 The General Hospital Corporation Affinity purification methods involving imidazole elution
US20040063153A1 (en) * 2002-08-12 2004-04-01 Tomas Jelinek Method for isolation of protein complexes using affinity binding
US8084032B2 (en) 2004-01-21 2011-12-27 Ajinomoto Co., Inc. Purification method which prevents denaturation of an antibody
UA112203C2 (en) 2011-11-11 2016-08-10 Юсб Фарма С.А. Fusion protein of a biospecific antibody that binds to human OX40 and serum human albumin
SI2776466T1 (en) 2011-11-11 2017-12-29 Ucb Biopharma Sprl Albumin binding antibodies and binding fragments thereof
GB201208370D0 (en) 2012-05-14 2012-06-27 Ucb Pharma Sa Antibodies
JP6236948B2 (en) * 2013-07-17 2017-11-29 東ソー株式会社 Antibody eluate and antibody purification method using the eluate
GB201411320D0 (en) 2014-06-25 2014-08-06 Ucb Biopharma Sprl Antibody construct
GB201506868D0 (en) 2015-04-22 2015-06-03 Ucb Biopharma Sprl Method for protein purification

Also Published As

Publication number Publication date
JP2022543187A (en) 2022-10-11
EP4007771A1 (en) 2022-06-08
BR112021023542A2 (en) 2022-03-22
CN114401984A (en) 2022-04-26
CA3142610A1 (en) 2021-02-11
US20220280887A1 (en) 2022-09-08
AU2020326087A1 (en) 2021-12-16
MX2022001349A (en) 2022-03-25
KR20220039744A (en) 2022-03-29
WO2021023619A1 (en) 2021-02-11
AR119546A1 (en) 2021-12-29
IL289959A (en) 2022-03-01

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