SG11202112781SA - Method, structures and system for nucleic acid sequence topology assembly for multiplexed profiling of proteins - Google Patents
Method, structures and system for nucleic acid sequence topology assembly for multiplexed profiling of proteinsInfo
- Publication number
- SG11202112781SA SG11202112781SA SG11202112781SA SG11202112781SA SG11202112781SA SG 11202112781S A SG11202112781S A SG 11202112781SA SG 11202112781S A SG11202112781S A SG 11202112781SA SG 11202112781S A SG11202112781S A SG 11202112781SA SG 11202112781S A SG11202112781S A SG 11202112781SA
- Authority
- SG
- Singapore
- Prior art keywords
- proteins
- structures
- nucleic acid
- acid sequence
- sequence topology
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54346—Nanoparticles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6804—Nucleic acid analysis using immunogens
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nanotechnology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SG10201904897UA SG10201904897UA (en) | 2019-05-30 | 2019-05-30 | Method, structures and system for nucleic acid sequence topology assembly for multiplexed profiling of proteins. |
PCT/SG2020/050298 WO2020242377A1 (en) | 2019-05-30 | 2020-05-19 | Method, structures and system for nucleic acid sequence topology assembly for multiplexed profiling of proteins |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202112781SA true SG11202112781SA (en) | 2021-12-30 |
Family
ID=73552995
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201904897UA SG10201904897UA (en) | 2019-05-30 | 2019-05-30 | Method, structures and system for nucleic acid sequence topology assembly for multiplexed profiling of proteins. |
SG11202112781SA SG11202112781SA (en) | 2019-05-30 | 2020-05-19 | Method, structures and system for nucleic acid sequence topology assembly for multiplexed profiling of proteins |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201904897UA SG10201904897UA (en) | 2019-05-30 | 2019-05-30 | Method, structures and system for nucleic acid sequence topology assembly for multiplexed profiling of proteins. |
Country Status (3)
Country | Link |
---|---|
US (1) | US20220236281A1 (en) |
SG (2) | SG10201904897UA (en) |
WO (1) | WO2020242377A1 (en) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8835358B2 (en) | 2009-12-15 | 2014-09-16 | Cellular Research, Inc. | Digital counting of individual molecules by stochastic attachment of diverse labels |
CN104364392B (en) | 2012-02-27 | 2018-05-25 | 赛卢拉研究公司 | For the composition and kit of numerator counts |
KR102536833B1 (en) | 2013-08-28 | 2023-05-26 | 벡톤 디킨슨 앤드 컴퍼니 | Massively parallel single cell analysis |
US10301677B2 (en) | 2016-05-25 | 2019-05-28 | Cellular Research, Inc. | Normalization of nucleic acid libraries |
CA3034924A1 (en) | 2016-09-26 | 2018-03-29 | Cellular Research, Inc. | Measurement of protein expression using reagents with barcoded oligonucleotide sequences |
CA3059559A1 (en) | 2017-06-05 | 2018-12-13 | Becton, Dickinson And Company | Sample indexing for single cells |
WO2020072380A1 (en) | 2018-10-01 | 2020-04-09 | Cellular Research, Inc. | Determining 5' transcript sequences |
WO2020154247A1 (en) | 2019-01-23 | 2020-07-30 | Cellular Research, Inc. | Oligonucleotides associated with antibodies |
WO2020167920A1 (en) | 2019-02-14 | 2020-08-20 | Cellular Research, Inc. | Hybrid targeted and whole transcriptome amplification |
EP4004231A1 (en) | 2019-07-22 | 2022-06-01 | Becton, Dickinson and Company | Single cell chromatin immunoprecipitation sequencing assay |
WO2021092386A1 (en) | 2019-11-08 | 2021-05-14 | Becton Dickinson And Company | Using random priming to obtain full-length v(d)j information for immune repertoire sequencing |
CN115244184A (en) | 2020-01-13 | 2022-10-25 | 贝克顿迪金森公司 | Methods and compositions for quantifying protein and RNA |
WO2021231779A1 (en) | 2020-05-14 | 2021-11-18 | Becton, Dickinson And Company | Primers for immune repertoire profiling |
US11932901B2 (en) | 2020-07-13 | 2024-03-19 | Becton, Dickinson And Company | Target enrichment using nucleic acid probes for scRNAseq |
CN116635533A (en) | 2020-11-20 | 2023-08-22 | 贝克顿迪金森公司 | Profiling of high and low expressed proteins |
CN113624823B (en) * | 2021-08-04 | 2023-06-06 | 中国科学院上海高等研究院 | Signal probe based on tetrahedral nano-structure DNA, preparation method and application thereof |
CN117110625B (en) * | 2023-08-25 | 2024-04-19 | 中国人民解放军陆军军医大学第二附属医院 | Application of DNA logic gate nano device in cell surface protein staining |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20180320241A1 (en) * | 2014-12-19 | 2018-11-08 | Roche Sequencing Solutions, Inc. | Methods for identifying multiple epitopes in selected sub-populations of cells |
WO2017100251A1 (en) * | 2015-12-08 | 2017-06-15 | President And Fellows Of Harvard College | Target detection using barcode conjugates and nucleic acid nanoarrays |
CN117551741A (en) * | 2017-03-31 | 2024-02-13 | 乌尔蒂维尤股份有限公司 | DNA-antigen exchange and amplification |
US11549135B2 (en) * | 2018-09-14 | 2023-01-10 | The Broad Institute, Inc. | Oligonucleotide-coupled antibodies for single cell or single complex protein measurements |
US20220106623A1 (en) * | 2018-11-21 | 2022-04-07 | Fred Hutchinson Cancer Research Center | Spatial mapping of cells and cell types in complex tissues |
-
2019
- 2019-05-30 SG SG10201904897UA patent/SG10201904897UA/en unknown
-
2020
- 2020-05-19 WO PCT/SG2020/050298 patent/WO2020242377A1/en active Application Filing
- 2020-05-19 US US17/615,115 patent/US20220236281A1/en active Pending
- 2020-05-19 SG SG11202112781SA patent/SG11202112781SA/en unknown
Also Published As
Publication number | Publication date |
---|---|
US20220236281A1 (en) | 2022-07-28 |
WO2020242377A1 (en) | 2020-12-03 |
SG10201904897UA (en) | 2020-12-30 |
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