SG11202112781SA - Method, structures and system for nucleic acid sequence topology assembly for multiplexed profiling of proteins - Google Patents

Method, structures and system for nucleic acid sequence topology assembly for multiplexed profiling of proteins

Info

Publication number
SG11202112781SA
SG11202112781SA SG11202112781SA SG11202112781SA SG11202112781SA SG 11202112781S A SG11202112781S A SG 11202112781SA SG 11202112781S A SG11202112781S A SG 11202112781SA SG 11202112781S A SG11202112781S A SG 11202112781SA SG 11202112781S A SG11202112781S A SG 11202112781SA
Authority
SG
Singapore
Prior art keywords
proteins
structures
nucleic acid
acid sequence
sequence topology
Prior art date
Application number
SG11202112781SA
Inventor
Huilin Shao
Noah Riandiputra Sundah
Ching Wan Chan
Tze Ping LOH
Original Assignee
Nat Univ Singapore
Nat Univ Hospital Singapore Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nat Univ Singapore, Nat Univ Hospital Singapore Pte Ltd filed Critical Nat Univ Singapore
Publication of SG11202112781SA publication Critical patent/SG11202112781SA/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346Nanoparticles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804Nucleic acid analysis using immunogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nanotechnology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
SG11202112781SA 2019-05-30 2020-05-19 Method, structures and system for nucleic acid sequence topology assembly for multiplexed profiling of proteins SG11202112781SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SG10201904897UA SG10201904897UA (en) 2019-05-30 2019-05-30 Method, structures and system for nucleic acid sequence topology assembly for multiplexed profiling of proteins.
PCT/SG2020/050298 WO2020242377A1 (en) 2019-05-30 2020-05-19 Method, structures and system for nucleic acid sequence topology assembly for multiplexed profiling of proteins

Publications (1)

Publication Number Publication Date
SG11202112781SA true SG11202112781SA (en) 2021-12-30

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201904897UA SG10201904897UA (en) 2019-05-30 2019-05-30 Method, structures and system for nucleic acid sequence topology assembly for multiplexed profiling of proteins.
SG11202112781SA SG11202112781SA (en) 2019-05-30 2020-05-19 Method, structures and system for nucleic acid sequence topology assembly for multiplexed profiling of proteins

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG10201904897UA SG10201904897UA (en) 2019-05-30 2019-05-30 Method, structures and system for nucleic acid sequence topology assembly for multiplexed profiling of proteins.

Country Status (3)

Country Link
US (1) US20220236281A1 (en)
SG (2) SG10201904897UA (en)
WO (1) WO2020242377A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8835358B2 (en) 2009-12-15 2014-09-16 Cellular Research, Inc. Digital counting of individual molecules by stochastic attachment of diverse labels
CN104364392B (en) 2012-02-27 2018-05-25 赛卢拉研究公司 For the composition and kit of numerator counts
KR102536833B1 (en) 2013-08-28 2023-05-26 벡톤 디킨슨 앤드 컴퍼니 Massively parallel single cell analysis
US10301677B2 (en) 2016-05-25 2019-05-28 Cellular Research, Inc. Normalization of nucleic acid libraries
CA3034924A1 (en) 2016-09-26 2018-03-29 Cellular Research, Inc. Measurement of protein expression using reagents with barcoded oligonucleotide sequences
CA3059559A1 (en) 2017-06-05 2018-12-13 Becton, Dickinson And Company Sample indexing for single cells
WO2020072380A1 (en) 2018-10-01 2020-04-09 Cellular Research, Inc. Determining 5' transcript sequences
WO2020154247A1 (en) 2019-01-23 2020-07-30 Cellular Research, Inc. Oligonucleotides associated with antibodies
WO2020167920A1 (en) 2019-02-14 2020-08-20 Cellular Research, Inc. Hybrid targeted and whole transcriptome amplification
EP4004231A1 (en) 2019-07-22 2022-06-01 Becton, Dickinson and Company Single cell chromatin immunoprecipitation sequencing assay
WO2021092386A1 (en) 2019-11-08 2021-05-14 Becton Dickinson And Company Using random priming to obtain full-length v(d)j information for immune repertoire sequencing
CN115244184A (en) 2020-01-13 2022-10-25 贝克顿迪金森公司 Methods and compositions for quantifying protein and RNA
WO2021231779A1 (en) 2020-05-14 2021-11-18 Becton, Dickinson And Company Primers for immune repertoire profiling
US11932901B2 (en) 2020-07-13 2024-03-19 Becton, Dickinson And Company Target enrichment using nucleic acid probes for scRNAseq
CN116635533A (en) 2020-11-20 2023-08-22 贝克顿迪金森公司 Profiling of high and low expressed proteins
CN113624823B (en) * 2021-08-04 2023-06-06 中国科学院上海高等研究院 Signal probe based on tetrahedral nano-structure DNA, preparation method and application thereof
CN117110625B (en) * 2023-08-25 2024-04-19 中国人民解放军陆军军医大学第二附属医院 Application of DNA logic gate nano device in cell surface protein staining

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180320241A1 (en) * 2014-12-19 2018-11-08 Roche Sequencing Solutions, Inc. Methods for identifying multiple epitopes in selected sub-populations of cells
WO2017100251A1 (en) * 2015-12-08 2017-06-15 President And Fellows Of Harvard College Target detection using barcode conjugates and nucleic acid nanoarrays
CN117551741A (en) * 2017-03-31 2024-02-13 乌尔蒂维尤股份有限公司 DNA-antigen exchange and amplification
US11549135B2 (en) * 2018-09-14 2023-01-10 The Broad Institute, Inc. Oligonucleotide-coupled antibodies for single cell or single complex protein measurements
US20220106623A1 (en) * 2018-11-21 2022-04-07 Fred Hutchinson Cancer Research Center Spatial mapping of cells and cell types in complex tissues

Also Published As

Publication number Publication date
US20220236281A1 (en) 2022-07-28
WO2020242377A1 (en) 2020-12-03
SG10201904897UA (en) 2020-12-30

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