SG11202111756UA - Gas-filled microvesicles - Google Patents

Gas-filled microvesicles

Info

Publication number
SG11202111756UA
SG11202111756UA SG11202111756UA SG11202111756UA SG11202111756UA SG 11202111756U A SG11202111756U A SG 11202111756UA SG 11202111756U A SG11202111756U A SG 11202111756UA SG 11202111756U A SG11202111756U A SG 11202111756UA SG 11202111756U A SG11202111756U A SG 11202111756UA
Authority
SG
Singapore
Prior art keywords
gas
filled microvesicles
microvesicles
filled
Prior art date
Application number
SG11202111756UA
Inventor
Philippe Bussat
Samir Cherkaoui
David Lazarus
Eric Allemann
Michel Schneider
Christian Guillot
Original Assignee
Bracco Suisse Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US16/688,540 external-priority patent/US20200360540A1/en
Application filed by Bracco Suisse Sa filed Critical Bracco Suisse Sa
Publication of SG11202111756UA publication Critical patent/SG11202111756UA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/22Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1277Processes for preparing; Proliposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Acoustics & Sound (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Meat, Egg Or Seafood Products (AREA)
SG11202111756UA 2019-05-15 2020-05-14 Gas-filled microvesicles SG11202111756UA (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201916413526A 2019-05-15 2019-05-15
US16/688,540 US20200360540A1 (en) 2019-05-15 2019-11-19 Freeze-dried product and gas-filled microvesicles suspension
US16/788,083 US20200360289A1 (en) 2019-05-15 2020-02-11 Freeze-dried product and gas-filled microvesicles suspension
PCT/EP2020/063560 WO2020229643A1 (en) 2019-05-15 2020-05-14 Gas-filled microvesicles

Publications (1)

Publication Number Publication Date
SG11202111756UA true SG11202111756UA (en) 2021-11-29

Family

ID=70738571

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11202111754PA SG11202111754PA (en) 2019-05-15 2020-05-14 Freeze-dried product and gas-filled microvesicles suspension
SG11202111756UA SG11202111756UA (en) 2019-05-15 2020-05-14 Gas-filled microvesicles

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG11202111754PA SG11202111754PA (en) 2019-05-15 2020-05-14 Freeze-dried product and gas-filled microvesicles suspension

Country Status (13)

Country Link
US (4) US20200360289A1 (en)
EP (2) EP3969064B1 (en)
JP (2) JP7357078B2 (en)
KR (3) KR20240010559A (en)
CN (2) CN113825529B (en)
AU (2) AU2020274620A1 (en)
BR (2) BR112021022185A2 (en)
CA (2) CA3137088C (en)
ES (1) ES2965028T3 (en)
IL (2) IL288094A (en)
SG (2) SG11202111754PA (en)
WO (2) WO2020229642A1 (en)
ZA (2) ZA202108052B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11717570B2 (en) * 2019-05-15 2023-08-08 Bracco Suisse Sa Gas-filled microvesicles
US20200360289A1 (en) * 2019-05-15 2020-11-19 Bracco Suisse Sa Freeze-dried product and gas-filled microvesicles suspension
CN115970010A (en) * 2021-10-14 2023-04-18 北京启慧生物医药有限公司 Lipid microbubble lyophilized powder composition and preparation method thereof
WO2023111332A1 (en) 2021-12-16 2023-06-22 Bracco Suisse Sa Method for extracting a fluorinated gas
WO2024133827A1 (en) 2022-12-21 2024-06-27 Bracco Suisse Sa Gas-filled microvesicles with perfluoro olefin

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5445813A (en) 1992-11-02 1995-08-29 Bracco International B.V. Stable microbubble suspensions as enhancement agents for ultrasound echography
US20010008626A1 (en) * 1990-04-02 2001-07-19 Michel Schneider Ultrasound contrast agents and methods of making and using them
IN172208B (en) * 1990-04-02 1993-05-01 Sint Sa
US20080063603A1 (en) 1990-04-02 2008-03-13 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US6139819A (en) 1995-06-07 2000-10-31 Imarx Pharmaceutical Corp. Targeted contrast agents for diagnostic and therapeutic use
WO1998018501A2 (en) 1996-10-28 1998-05-07 Marsden, John, Christopher Improvements in or relating to diagnostic/therapeutic agents
GB9809084D0 (en) 1998-04-28 1998-06-24 Nycomed Imaging As Improvements in or relating to diagnostic/therapeutic agents
CA2432474C (en) 2000-12-23 2012-06-26 Dyax Corp. Fibrin binding polypeptides useful inter alia in medical imaging processes
ATE299378T1 (en) * 2001-01-31 2005-07-15 Bracco Research Sa LYOPHILIZABLE CONTRAST AGENT CONTAINING GAS-FILLED MICROBUBBLES
EP2301587B1 (en) 2002-03-01 2014-06-25 Dyax Corp. KDR and VEGF/KDR binding peptides and their use in diagnosis
CA2477935C (en) 2002-03-01 2015-01-06 Bracco International Bv Multivalent constructs for therapeutic and diagnostic applications
KR101076053B1 (en) 2003-02-04 2011-10-21 브라코 인터내셔날 비.브이. Ultrasound contrast agents and process for the preparation thereof
US20050025710A1 (en) 2003-07-29 2005-02-03 Michel Schneider Reconstitutable formulation and aqueous suspension of gas-filled microvesicles for diagnostic imaging
AU2004308756B2 (en) 2003-12-22 2010-06-24 Bracco Suisse S.A. Gas-filled microvesicle assembly for contrast imaging
CN103204911B (en) 2005-12-09 2015-04-01 布拉科瑞士有限公司 Targeting Vector-phospholipid Conjugates
WO2008075192A2 (en) 2006-12-19 2008-06-26 Bracco International Bv Targeting and therapeutic compounds and gas-filled microvesicles comprising said com ounds
US20100008978A1 (en) 2008-05-09 2010-01-14 The Regents Of The University Of California Nanoparticles effective for internalization into cells
CA2748995C (en) 2008-10-07 2018-01-16 Bracco Suisse Sa Targeting construct comprising anti-polymer antibody and liposomes or microvesicles binding to the same
CN108926535B (en) 2011-02-01 2020-12-29 常州长吉生物技术开发有限公司 SapC-phospholipid nano vesicle freeze-dried preparation, preparation method and application thereof
WO2015192093A1 (en) 2014-06-12 2015-12-17 Unger Evan C Phospholipid composition and microbubbles and emulsions formed using same
JP6803839B2 (en) * 2014-12-18 2020-12-23 ブラッコ・スイス・ソシエテ・アノニムBracco Suisse SA Formulation of targeted gas-filled microvesicles
AU2016381806B2 (en) 2015-12-29 2021-04-15 Thermogenesis Corporation Cell separation devices, systems, and methods
AU2017260532A1 (en) 2016-05-04 2018-11-22 Lantheus Medical Imaging, Inc. Methods and devices for preparation of ultrasound contrast agents
US9789210B1 (en) 2016-07-06 2017-10-17 Lantheus Medical Imaging, Inc. Methods for making ultrasound contrast agents
US20200360289A1 (en) * 2019-05-15 2020-11-19 Bracco Suisse Sa Freeze-dried product and gas-filled microvesicles suspension

Also Published As

Publication number Publication date
ZA202108096B (en) 2022-07-27
CA3137088A1 (en) 2020-11-19
CN113825529B (en) 2024-04-19
EP3969064A1 (en) 2022-03-23
BR112021021791A2 (en) 2021-12-21
US11723869B2 (en) 2023-08-15
JP2022532344A (en) 2022-07-14
CA3137089A1 (en) 2020-11-19
BR112021022185A2 (en) 2021-12-21
IL288094A (en) 2022-01-01
WO2020229643A1 (en) 2020-11-19
ZA202108052B (en) 2022-09-28
US20220202719A1 (en) 2022-06-30
CA3137088C (en) 2023-04-04
IL288095A (en) 2022-01-01
KR20240010559A (en) 2024-01-23
ES2965028T3 (en) 2024-04-10
KR20220008827A (en) 2022-01-21
EP3969065A1 (en) 2022-03-23
KR102624471B1 (en) 2024-01-15
JP7148742B2 (en) 2022-10-05
KR102626600B1 (en) 2024-01-18
WO2020229642A1 (en) 2020-11-19
JP7357078B2 (en) 2023-10-05
AU2020274620A1 (en) 2021-11-11
US20200360289A1 (en) 2020-11-19
AU2020276679A1 (en) 2021-11-11
KR20220008277A (en) 2022-01-20
US11426352B2 (en) 2022-08-30
US20230414517A1 (en) 2023-12-28
CN113825529A (en) 2021-12-21
CN113811335A (en) 2021-12-17
SG11202111754PA (en) 2021-11-29
US20220354795A1 (en) 2022-11-10
JP2022527227A (en) 2022-05-31
EP3969064B1 (en) 2023-09-06

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