SG11202110683WA - Solid forms of an orally-delivered beta-lactamase inhibitor and uses thereof - Google Patents

Solid forms of an orally-delivered beta-lactamase inhibitor and uses thereof

Info

Publication number
SG11202110683WA
SG11202110683WA SG11202110683WA SG11202110683WA SG11202110683WA SG 11202110683W A SG11202110683W A SG 11202110683WA SG 11202110683W A SG11202110683W A SG 11202110683WA SG 11202110683W A SG11202110683W A SG 11202110683WA SG 11202110683W A SG11202110683W A SG 11202110683WA
Authority
SG
Singapore
Prior art keywords
orally
solid forms
lactamase inhibitor
beta
delivered
Prior art date
Application number
SG11202110683WA
Inventor
Christopher J Burns
Lawrence Rosen
Stephen M Condon
Eugen F Mesaros
Allison L Zulli
Robert E Lee Trout
Yijun Deng
Steven A Boyd
Robert Simpson
Original Assignee
Venatorx Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Venatorx Pharmaceuticals Inc filed Critical Venatorx Pharmaceuticals Inc
Publication of SG11202110683WA publication Critical patent/SG11202110683WA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • C07F5/025Boronic and borinic acid compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/69Boron compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SG11202110683WA 2019-04-02 2020-04-01 Solid forms of an orally-delivered beta-lactamase inhibitor and uses thereof SG11202110683WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962828349P 2019-04-02 2019-04-02
PCT/US2020/026114 WO2020205932A1 (en) 2019-04-02 2020-04-01 Solid forms of an orally-delivered beta-lactamase inhibitor and uses thereof

Publications (1)

Publication Number Publication Date
SG11202110683WA true SG11202110683WA (en) 2021-10-28

Family

ID=72666564

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202110683WA SG11202110683WA (en) 2019-04-02 2020-04-01 Solid forms of an orally-delivered beta-lactamase inhibitor and uses thereof

Country Status (14)

Country Link
US (1) US20220194964A1 (en)
EP (1) EP3946364A4 (en)
JP (1) JP2022529212A (en)
KR (1) KR20210146979A (en)
CN (1) CN113905741A (en)
AU (1) AU2020256179A1 (en)
BR (1) BR112021019656A2 (en)
CA (1) CA3135614A1 (en)
EA (1) EA202192669A1 (en)
IL (1) IL286850A (en)
MA (1) MA55557A (en)
SG (1) SG11202110683WA (en)
TW (1) TW202102230A (en)
WO (1) WO2020205932A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2730013T3 (en) 2013-01-10 2019-11-07 Venatorx Pharmaceuticals Inc Betalactamase inhibitors
RU2686740C2 (en) 2014-06-11 2019-04-30 Венаторкс Фармасьютикалс, Инк. Beta-lactamase inhibitors
US10399996B2 (en) 2015-09-11 2019-09-03 VenatoRx Pharmaceuticals, Inc. Beta-lactamase inhibitors
US11267826B2 (en) 2017-05-26 2022-03-08 VenatoRx Pharmaceuticals, Inc. Penicillin-binding protein inhibitors
WO2018218190A1 (en) 2017-05-26 2018-11-29 VenatoRx Pharmaceuticals, Inc. Penicillin-binding protein inhibitors
SG11202105505TA (en) * 2018-11-29 2021-06-29 Venatorx Pharmaceuticals Inc Combination compositions comprising a beta-lactamase inhibitor and uses thereof
KR20230062075A (en) 2021-10-29 2023-05-09 코웨이 주식회사 Evaporator for making ice

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100292185A1 (en) * 2009-05-12 2010-11-18 Burns Christopher J Beta-lactamase inhibitors
US9422314B2 (en) * 2012-12-07 2016-08-23 VenatoRx Pharmaceuticals, Inc. Beta-lactamase inhibitors
RU2686740C2 (en) * 2014-06-11 2019-04-30 Венаторкс Фармасьютикалс, Инк. Beta-lactamase inhibitors
WO2017100537A1 (en) * 2015-12-10 2017-06-15 VenatoRx Pharmaceuticals, Inc. Beta-lactamase inhibitors
SG11202105505TA (en) * 2018-11-29 2021-06-29 Venatorx Pharmaceuticals Inc Combination compositions comprising a beta-lactamase inhibitor and uses thereof

Also Published As

Publication number Publication date
MA55557A (en) 2022-02-09
EA202192669A1 (en) 2022-03-01
JP2022529212A (en) 2022-06-20
EP3946364A1 (en) 2022-02-09
BR112021019656A2 (en) 2022-01-18
KR20210146979A (en) 2021-12-06
AU2020256179A1 (en) 2021-11-18
EP3946364A4 (en) 2023-01-18
CA3135614A1 (en) 2020-10-08
IL286850A (en) 2021-10-31
WO2020205932A1 (en) 2020-10-08
CN113905741A (en) 2022-01-07
TW202102230A (en) 2021-01-16
US20220194964A1 (en) 2022-06-23

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