SG11202110643YA - Novel compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders - Google Patents

Novel compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders

Info

Publication number
SG11202110643YA
SG11202110643YA SG11202110643YA SG11202110643YA SG11202110643YA SG 11202110643Y A SG11202110643Y A SG 11202110643YA SG 11202110643Y A SG11202110643Y A SG 11202110643YA SG 11202110643Y A SG11202110643Y A SG 11202110643YA SG 11202110643Y A SG11202110643Y A SG 11202110643YA
Authority
SG
Singapore
Prior art keywords
treatment
pharmaceutical compositions
novel compounds
inflammatory disorders
disorders
Prior art date
Application number
SG11202110643YA
Inventor
Oscar Mammoliti
Reginald Brys
Gregory Newsome
Marielle Babel
Original Assignee
Galapagos Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galapagos Nv filed Critical Galapagos Nv
Publication of SG11202110643YA publication Critical patent/SG11202110643YA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG11202110643YA 2019-03-29 2020-03-24 Novel compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders SG11202110643YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1904375.1A GB201904375D0 (en) 2019-03-29 2019-03-29 Novel compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders
PCT/EP2020/058061 WO2020200898A1 (en) 2019-03-29 2020-03-24 Novel compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders

Publications (1)

Publication Number Publication Date
SG11202110643YA true SG11202110643YA (en) 2021-10-28

Family

ID=66442789

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202110643YA SG11202110643YA (en) 2019-03-29 2020-03-24 Novel compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders

Country Status (13)

Country Link
US (1) US20220296573A1 (en)
EP (1) EP3947374A1 (en)
JP (1) JP2022526553A (en)
KR (1) KR20210143905A (en)
CN (1) CN113677678A (en)
AU (1) AU2020252900A1 (en)
BR (1) BR112021019099A2 (en)
CA (1) CA3134732A1 (en)
GB (1) GB201904375D0 (en)
IL (1) IL286688A (en)
MX (1) MX2021011574A (en)
SG (1) SG11202110643YA (en)
WO (1) WO2020200898A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230059584A (en) 2021-10-26 2023-05-03 주식회사 엘지에너지솔루션 Manufacturing method of electrode assembly
WO2023098857A1 (en) * 2021-12-03 2023-06-08 武汉人福创新药物研发中心有限公司 Irak4 inhibitor and use thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7504412B2 (en) * 2003-08-15 2009-03-17 Banyu Pharmaceuticals, Co., Ltd. Imidazopyridine derivatives
CN1950372A (en) * 2004-05-10 2007-04-18 万有制药株式会社 Imidazopyridine compound
US9169260B2 (en) * 2011-03-22 2015-10-27 Merck Sharp & Dohme Corp. Amidopyrazole inhibitors of interleukin receptor-associated kinases
EP3760630A1 (en) * 2013-03-14 2021-01-06 Galapagos N.V. Novel compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders
KR20160115933A (en) * 2014-01-10 2016-10-06 오리진 디스커버리 테크놀로지스 리미티드 Indazole compounds as irak4 inhibitors
CN108473498B (en) * 2015-12-22 2021-11-02 豪夫迈·罗氏有限公司 Pyrazolo [1,5a ] pyrimidine derivatives as IRAK4 modulators
CN110835338A (en) * 2018-08-17 2020-02-25 浙江海正药业股份有限公司 Imidazopyridine derivative, preparation method and medical application thereof

Also Published As

Publication number Publication date
EP3947374A1 (en) 2022-02-09
BR112021019099A2 (en) 2021-11-30
CA3134732A1 (en) 2020-10-08
KR20210143905A (en) 2021-11-29
AU2020252900A1 (en) 2021-11-25
IL286688A (en) 2021-10-31
GB201904375D0 (en) 2019-05-15
US20220296573A1 (en) 2022-09-22
MX2021011574A (en) 2021-10-13
JP2022526553A (en) 2022-05-25
CN113677678A (en) 2021-11-19
WO2020200898A1 (en) 2020-10-08

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