SG11202110602XA - Method for obtaining or maintaining abcg2-positive corneal limbal stem cells - Google Patents

Method for obtaining or maintaining abcg2-positive corneal limbal stem cells

Info

Publication number
SG11202110602XA
SG11202110602XA SG11202110602XA SG11202110602XA SG11202110602XA SG 11202110602X A SG11202110602X A SG 11202110602XA SG 11202110602X A SG11202110602X A SG 11202110602XA SG 11202110602X A SG11202110602X A SG 11202110602XA SG 11202110602X A SG11202110602X A SG 11202110602XA
Authority
SG
Singapore
Prior art keywords
abcg2
maintaining
obtaining
stem cells
limbal stem
Prior art date
Application number
SG11202110602XA
Inventor
Meri Vattulainen
Keijo Viiri
Tanja Ilmarinen
Heli Skottman
Original Assignee
Stemsight Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stemsight Oy filed Critical Stemsight Oy
Publication of SG11202110602XA publication Critical patent/SG11202110602XA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40—Regulators of development
    • C12N2501/415—Wnt; Frizzeled
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/998—Proteins not provided for elsewhere

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Neurosurgery (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SG11202110602XA 2019-04-01 2020-03-31 Method for obtaining or maintaining abcg2-positive corneal limbal stem cells SG11202110602XA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20195258 2019-04-01
PCT/FI2020/050210 WO2020201629A1 (en) 2019-04-01 2020-03-31 Method for obtaining or maintaining abcg2-positive corneal limbal stem cells

Publications (1)

Publication Number Publication Date
SG11202110602XA true SG11202110602XA (en) 2021-10-28

Family

ID=70285709

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202110602XA SG11202110602XA (en) 2019-04-01 2020-03-31 Method for obtaining or maintaining abcg2-positive corneal limbal stem cells

Country Status (8)

Country Link
US (1) US20220340871A1 (en)
EP (1) EP3947651A1 (en)
JP (1) JP2022528737A (en)
KR (1) KR20210145178A (en)
CA (1) CA3133939A1 (en)
IL (1) IL286623A (en)
SG (1) SG11202110602XA (en)
WO (1) WO2020201629A1 (en)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2604659T3 (en) 2013-04-03 2017-03-08 Tampereen Yliopisto Methods and means for differentiation of eye cells
KR20170020527A (en) * 2014-06-27 2017-02-22 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 Cultured mammalian limbal stem cells, methods for generating the same, and uses thereof
KR101746552B1 (en) * 2015-04-14 2017-06-13 가톨릭대학교 산학협력단 Method of inducing differentiation of stem cell into corneal limbal stem cell
KR102029931B1 (en) * 2016-08-10 2019-10-08 가톨릭대학교 산학협력단 Method for Culturing Cornea Stem Cell Like Cell by Inducing Differentiation of Induced Pluripotent Stem Cell Using Protein Ligand and System for the Same
US20190264171A1 (en) 2016-08-24 2019-08-29 Tampereen Yliopisto Differentiation of pluripotent stem cells into corneal cells

Also Published As

Publication number Publication date
JP2022528737A (en) 2022-06-15
WO2020201629A1 (en) 2020-10-08
CA3133939A1 (en) 2020-10-08
EP3947651A1 (en) 2022-02-09
KR20210145178A (en) 2021-12-01
IL286623A (en) 2021-10-31
US20220340871A1 (en) 2022-10-27

Similar Documents

Publication Publication Date Title
EP3741844A4 (en) Method for deriving corneal endothelium replacement cells from ips cells
HK1257561A1 (en) Immortalized stem cells, and method for producing same
SG11202109760YA (en) Electropolishing method
EP3340997A4 (en) Methods for stem cell transplantation
EP4008787A4 (en) Method for preparing induced pluripotent stem cells by reprogramming somatic cells
EP3856894C0 (en) Methods for differentiating mesenchymal stem cells
IL274746A (en) Method for culture of cells
EP3845634A4 (en) Composition and method for preserving or culturing ocular cells
IL277878A (en) Compositions and methods for stem cell transplant
EP3666971A4 (en) Method for manufacturing artificial leather
EP3587559A4 (en) Production method for artificial pluripotent stem cells
EP3578641A4 (en) Method for preparing dental pulp stem cells from cells derived from dental pulp tissue
EP3527982A4 (en) Method for selecting high-efficacy stem cell by using downregulation in expression or activity of socs
EP3862428A4 (en) Method for extending telomere of cell
EP3842526A4 (en) Method for cultivating or inducing cells
IL289807A (en) Selective laser simulation of corneal stem cells
EP3508569A4 (en) Method for obtaining microglia from pluripotent stem cells
GB201805287D0 (en) Haematoietic stem cell treatment
GB201708554D0 (en) A method for the generation of induced pluirpotent stem cells
EP3862424A4 (en) Method and vessel for preserving corneal endothelial cells
EP3251703A4 (en) Material for intraocular lenses and method for preserving material for intraocular lenses
EP3778871A4 (en) Method for producing stem cell-derived lacrimal gland tissue
IL286623A (en) Method for obtaining or maintaining abcg2-positive corneal limbal stem cells
EP3597734A4 (en) Method for producing helper t cells from pluripotent stem cells
GB201805308D0 (en) Manufacturing methods for prosthetics