SG11202110472WA - Methods of treating squamous cell carcinomas with farnesyltransferase inhibitors - Google Patents

Methods of treating squamous cell carcinomas with farnesyltransferase inhibitors

Info

Publication number
SG11202110472WA
SG11202110472WA SG11202110472WA SG11202110472WA SG11202110472WA SG 11202110472W A SG11202110472W A SG 11202110472WA SG 11202110472W A SG11202110472W A SG 11202110472WA SG 11202110472W A SG11202110472W A SG 11202110472WA SG 11202110472W A SG11202110472W A SG 11202110472WA
Authority
SG
Singapore
Prior art keywords
methods
squamous cell
cell carcinomas
farnesyltransferase inhibitors
treating squamous
Prior art date
Application number
SG11202110472WA
Inventor
Francis Burrows
Yi Liu
Original Assignee
Kura Oncology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kura Oncology Inc filed Critical Kura Oncology Inc
Publication of SG11202110472WA publication Critical patent/SG11202110472WA/en

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    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/223—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of alpha-aminoacids
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/46434—Antigens related to induction of tolerance to non-self
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    • A61K39/4643—Vertebrate antigens
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    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
SG11202110472WA 2019-03-29 2020-03-27 Methods of treating squamous cell carcinomas with farnesyltransferase inhibitors SG11202110472WA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962826771P 2019-03-29 2019-03-29
US202062992749P 2020-03-20 2020-03-20
PCT/US2020/025149 WO2020205486A1 (en) 2019-03-29 2020-03-27 Methods of treating squamous cell carcinomas with farnesyltransferase inhibitors

Publications (1)

Publication Number Publication Date
SG11202110472WA true SG11202110472WA (en) 2021-10-28

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ID=70465263

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SG11202110472WA SG11202110472WA (en) 2019-03-29 2020-03-27 Methods of treating squamous cell carcinomas with farnesyltransferase inhibitors

Country Status (11)

Country Link
US (1) US11672774B2 (en)
EP (1) EP3946338A1 (en)
JP (1) JP2022527495A (en)
KR (1) KR20210144778A (en)
CN (1) CN113795253A (en)
AU (1) AU2020254492A1 (en)
CA (1) CA3134825A1 (en)
IL (1) IL286749A (en)
SG (1) SG11202110472WA (en)
TW (1) TW202043487A (en)
WO (1) WO2020205486A1 (en)

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JP2022517222A (en) 2019-01-10 2022-03-07 ミラティ セラピューティクス， インコーポレイテッド KRAS G12C inhibitor
BR112022003543A2 (en) 2019-08-29 2022-05-24 Array Biopharma Inc kras g12 inhibitors
US11890285B2 (en) 2019-09-24 2024-02-06 Mirati Therapeutics, Inc. Combination therapies
AU2020405170A1 (en) 2019-12-20 2022-06-30 Mirati Therapeutics, Inc. SOS1 inhibitors
WO2023196888A1 (en) 2022-04-08 2023-10-12 Kura Oncology, Inc. Methods of treating head and neck squamous cell carcinoma

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