SG11202109575UA - Fused ring pyrimidone derivatives for use in the treatment of hbv infection or of hbv-induced diseases - Google Patents

Fused ring pyrimidone derivatives for use in the treatment of hbv infection or of hbv-induced diseases

Info

Publication number
SG11202109575UA
SG11202109575UA SG11202109575UA SG11202109575UA SG11202109575UA SG 11202109575U A SG11202109575U A SG 11202109575UA SG 11202109575U A SG11202109575U A SG 11202109575UA SG 11202109575U A SG11202109575U A SG 11202109575UA SG 11202109575U A SG11202109575U A SG 11202109575UA
Authority
SG
Singapore
Prior art keywords
hbv
treatment
fused ring
induced diseases
pyrimidone derivatives
Prior art date
Application number
SG11202109575UA
Inventor
Sandrine Grosse
Jan Berke
Meng-Yang Hsiao
Lili Hu
Edgar Jacoby
Tim Jonckers
Bart Kesteleyn
Stefaan Last
Lamenca Carolina Martinez
Mathieu Perrier
Serge Pieters
Pierre Raboisson
Abdellah Tahri
Koen Vandyck
Wim Verschueren
Original Assignee
Janssen Sciences Ireland Unlimited Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Sciences Ireland Unlimited Co filed Critical Janssen Sciences Ireland Unlimited Co
Publication of SG11202109575UA publication Critical patent/SG11202109575UA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
SG11202109575UA 2019-03-14 2020-03-13 Fused ring pyrimidone derivatives for use in the treatment of hbv infection or of hbv-induced diseases SG11202109575UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP19162954 2019-03-14
PCT/EP2020/056884 WO2020182990A1 (en) 2019-03-14 2020-03-13 Fused ring pyrimidone derivatives for use in the treatment of hbv infection or of hbv-induced diseases

Publications (1)

Publication Number Publication Date
SG11202109575UA true SG11202109575UA (en) 2021-09-29

Family

ID=65817822

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202109575UA SG11202109575UA (en) 2019-03-14 2020-03-13 Fused ring pyrimidone derivatives for use in the treatment of hbv infection or of hbv-induced diseases

Country Status (23)

Country Link
US (1) US20230091047A1 (en)
EP (1) EP3938362A1 (en)
JP (1) JP2022524456A (en)
KR (1) KR20210139319A (en)
CN (1) CN113710667A (en)
AR (1) AR118358A1 (en)
AU (1) AU2020235270A1 (en)
BR (1) BR112021017415A2 (en)
CA (1) CA3132531A1 (en)
CL (1) CL2021002390A1 (en)
CO (1) CO2021011295A2 (en)
CR (1) CR20210482A (en)
DO (1) DOP2021000185A (en)
EA (1) EA202192512A1 (en)
EC (1) ECSP21067189A (en)
IL (1) IL286210A (en)
JO (1) JOP20210249A1 (en)
MA (1) MA55286A (en)
MX (1) MX2021011107A (en)
PE (1) PE20212325A1 (en)
SG (1) SG11202109575UA (en)
TW (1) TW202100524A (en)
WO (1) WO2020182990A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202227435A (en) * 2020-09-11 2022-07-16 愛爾蘭商健生科學愛爾蘭無限公司 Fused ring pyrimidone derivatives for use in the treatment of hbv infection or of hbv-induced diseases
CN116724038A (en) * 2020-10-21 2023-09-08 安力高医药股份有限公司 Bicyclic compounds
WO2022266193A1 (en) * 2021-06-18 2022-12-22 Aligos Therapeutics, Inc. Bicyclic compounds
US20230374008A1 (en) * 2022-04-20 2023-11-23 Aligos Therapeutics, Inc. Bicyclic compounds
WO2023205653A1 (en) * 2022-04-20 2023-10-26 Aligos Therapeutics, Inc. Bicyclic compounds
WO2024015425A1 (en) 2022-07-14 2024-01-18 Fmc Corporation Herbicidal benzoxazines
US20240150351A1 (en) * 2022-09-30 2024-05-09 Aligos Therapeutics, Inc. Bicyclic compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2078719A4 (en) 2006-09-28 2009-11-11 Dainippon Sumitomo Pharma Co Compound having bicyclic pyrimidine structure and pharmaceutical composition comprising the compound
JP2010524940A (en) * 2007-04-20 2010-07-22 シェーリング コーポレイション Pyrimidinone derivatives and methods for their use
CN101854597B (en) 2009-04-03 2015-06-03 中兴通讯股份有限公司 Transmission method and system of large fusion IP (Internet Protocol) message
WO2011111880A1 (en) * 2010-03-08 2011-09-15 주식회사 메디젠텍 Pharmaceutical composition for treating or preventing diseases caused by the nuclear export of gsk3, including a compound for inhibiting the nuclear export of gsk3
JP2012126698A (en) * 2010-12-17 2012-07-05 Tsutomu Takeuchi Binding inhibitor of baff containing tetrahydropyridopyrimidine derivative as effective component
JP6713465B2 (en) * 2014-12-30 2020-06-24 ノヴィラ・セラピューティクス・インコーポレイテッド Derivatives and methods for treating hepatitis B infection
CN110088104B (en) * 2016-11-03 2022-04-12 豪夫迈·罗氏有限公司 Tetrahydropyridopyrimidine compounds for the treatment and prevention of hepatitis B virus infection

Also Published As

Publication number Publication date
CL2021002390A1 (en) 2022-04-22
EP3938362A1 (en) 2022-01-19
CN113710667A (en) 2021-11-26
AU2020235270A1 (en) 2021-08-12
ECSP21067189A (en) 2021-11-18
JP2022524456A (en) 2022-05-02
IL286210A (en) 2021-10-31
CR20210482A (en) 2021-11-09
JOP20210249A1 (en) 2023-01-30
CA3132531A1 (en) 2020-09-17
DOP2021000185A (en) 2022-01-16
MA55286A (en) 2022-01-19
PE20212325A1 (en) 2021-12-14
AR118358A1 (en) 2021-09-29
US20230091047A1 (en) 2023-03-23
BR112021017415A2 (en) 2022-02-01
TW202100524A (en) 2021-01-01
KR20210139319A (en) 2021-11-22
WO2020182990A1 (en) 2020-09-17
CO2021011295A2 (en) 2021-09-20
EA202192512A1 (en) 2022-02-16
MX2021011107A (en) 2022-01-19

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