SG11202109251QA - Multi-Channel Microfluidic Blood Coagulation Detection Chip Having Five-Layer Structure - Google Patents
Multi-Channel Microfluidic Blood Coagulation Detection Chip Having Five-Layer StructureInfo
- Publication number
- SG11202109251QA SG11202109251QA SG11202109251QA SG11202109251QA SG11202109251QA SG 11202109251Q A SG11202109251Q A SG 11202109251QA SG 11202109251Q A SG11202109251Q A SG 11202109251QA SG 11202109251Q A SG11202109251Q A SG 11202109251QA SG 11202109251Q A SG11202109251Q A SG 11202109251QA
- Authority
- SG
- Singapore
- Prior art keywords
- layer structure
- blood coagulation
- detection chip
- channel microfluidic
- coagulation detection
- Prior art date
Links
- 230000023555 blood coagulation Effects 0.000 title 1
- 238000001514 detection method Methods 0.000 title 1
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5025—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502723—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by venting arrangements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
- G01N27/3272—Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/4905—Determining clotting time of blood
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
- B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0684—Venting, avoiding backpressure, avoid gas bubbles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/14—Process control and prevention of errors
- B01L2200/141—Preventing contamination, tampering
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/16—Reagents, handling or storing thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0645—Electrodes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0663—Whole sensors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0887—Laminated structure
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Clinical Laboratory Science (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Electrochemistry (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- Ecology (AREA)
- Food Science & Technology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201910154636.4A CN109682878A (zh) | 2019-03-01 | 2019-03-01 | 一种具有五层结构的多通道微流体凝血检测芯片 |
PCT/CN2020/084386 WO2020177773A1 (zh) | 2019-03-01 | 2020-04-13 | 一种具有五层结构的多通道微流体凝血检测芯片 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202109251QA true SG11202109251QA (en) | 2021-09-29 |
Family
ID=66196221
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202109251QA SG11202109251QA (en) | 2019-03-01 | 2020-04-13 | Multi-Channel Microfluidic Blood Coagulation Detection Chip Having Five-Layer Structure |
Country Status (6)
Country | Link |
---|---|
US (1) | US20220143609A1 (de) |
EP (1) | EP3995822A4 (de) |
CN (1) | CN109682878A (de) |
MA (1) | MA56460A (de) |
SG (1) | SG11202109251QA (de) |
WO (1) | WO2020177773A1 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11690566B2 (en) | 2017-11-21 | 2023-07-04 | MX3 Diagnostics, Inc. | Saliva testing system |
CN109682878A (zh) * | 2019-03-01 | 2019-04-26 | 南京岚煜生物科技有限公司 | 一种具有五层结构的多通道微流体凝血检测芯片 |
CN110244066A (zh) * | 2019-07-01 | 2019-09-17 | 北京乐普医疗科技有限责任公司 | 一种干式电化学法凝血酶原时间检测卡及制备方法 |
US11701036B2 (en) * | 2019-07-10 | 2023-07-18 | MX3 Diagnostics, Inc. | Saliva test strip and method |
CN112986553A (zh) * | 2019-12-14 | 2021-06-18 | 南京岚煜生物科技有限公司 | 一种免疫电极的制备方法 |
EP4095512A4 (de) * | 2020-01-23 | 2023-01-18 | BOE Technology Group Co., Ltd. | Mikrofluidische kanalrückplatte und herstellungsverfahren dafür und mikrofluidischer detektionschip |
JP2023513053A (ja) | 2020-01-30 | 2023-03-30 | エムエックススリー・ダイアグノスティクス・インコーポレイテッド | 生体液試料の評価 |
CN111363664B (zh) * | 2020-04-24 | 2023-06-30 | 吉林医药学院 | 一种基于三层微芯片检测的lamp检测芯片及其控制方法 |
CN112191284A (zh) * | 2020-06-18 | 2021-01-08 | 天津大学 | 微流控超声电化学片上实验室分析平台 |
CN112934284A (zh) * | 2021-03-29 | 2021-06-11 | 西北大学 | 一种高通量微流控芯片及制备方法 |
CN113441198B (zh) * | 2021-05-31 | 2023-01-10 | 深圳市博德致远生物技术有限公司 | 一种微流控芯片制备方法 |
CN113649089A (zh) * | 2021-07-16 | 2021-11-16 | 法国介观生物技术有限公司 | 一种微流控芯片 |
CN114839241A (zh) * | 2022-02-28 | 2022-08-02 | 京东方科技集团股份有限公司 | 检测基板及其检测方法、检测装置 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1315570A4 (de) * | 2000-08-03 | 2006-12-13 | Caliper Life Sciences Inc | Verfahren und vorrichtungen für fluidförderung mit hohem durchsatz |
AU2003215340A1 (en) * | 2002-02-22 | 2003-09-09 | Nanostream, Inc. | Ratiometric dilution devices and methods |
US7674616B2 (en) * | 2006-09-14 | 2010-03-09 | Hemosense, Inc. | Device and method for measuring properties of a sample |
JP5303028B2 (ja) * | 2008-04-07 | 2013-10-02 | イーアイ・スペクトラ・エルエルシー | マイクロ流体センサの製造方法 |
KR20100083029A (ko) * | 2009-01-12 | 2010-07-21 | 삼성전자주식회사 | 전기화학적 방법에 의하여 시료에 포함된 전해질 검출이 가능한 디스크형 미세유동장치 |
CN103913489B (zh) * | 2013-01-09 | 2015-06-10 | 北京怡成生物电子技术股份有限公司 | 用于体液中物质实时检测的微型生物芯片 |
US9458488B2 (en) * | 2013-03-15 | 2016-10-04 | Nanomix, Inc. | Point of care sensor systems |
CN103386338A (zh) * | 2013-08-07 | 2013-11-13 | 苏州扬清芯片科技有限公司 | 一种微流控组合化学反应芯片 |
US20150140671A1 (en) * | 2013-11-18 | 2015-05-21 | Johnson Electric S.A. | Method and system for assembling a microfluidic sensor |
KR101527768B1 (ko) * | 2014-09-10 | 2015-06-12 | 주식회사 엑세스바이오코리아 | 미세유체 칩 및 진단기기 |
WO2016087957A1 (en) * | 2014-12-05 | 2016-06-09 | Diasys Diagnostics India Private Limited | Multiplexed microfluidic device |
CN106391151B (zh) * | 2016-08-31 | 2018-11-09 | 清华大学 | 适合于批量化生产的多层微流体芯片制作方法 |
CN108452854A (zh) * | 2018-04-04 | 2018-08-28 | 苏州芯海智能科技有限公司 | 一种微流控芯片及其应用 |
CN108398470B (zh) | 2018-04-13 | 2024-01-30 | 广州万孚生物技术股份有限公司 | 血液活化凝血时间测定生物传感器及其制作方法 |
CN108745429B (zh) * | 2018-06-12 | 2023-11-24 | 南京岚煜生物科技有限公司 | 一种多通道快速检测微流体检测芯片 |
CN109358101A (zh) * | 2018-08-31 | 2019-02-19 | 浙江大学山东工业技术研究院 | 一种多参数检测的电化学传感器电极试片 |
CN109682878A (zh) * | 2019-03-01 | 2019-04-26 | 南京岚煜生物科技有限公司 | 一种具有五层结构的多通道微流体凝血检测芯片 |
CN209640280U (zh) * | 2019-03-01 | 2019-11-15 | 南京岚煜生物科技有限公司 | 一种具有五层结构的多通道微流体凝血检测芯片 |
-
2019
- 2019-03-01 CN CN201910154636.4A patent/CN109682878A/zh active Pending
-
2020
- 2020-04-13 SG SG11202109251QA patent/SG11202109251QA/en unknown
- 2020-04-13 WO PCT/CN2020/084386 patent/WO2020177773A1/zh unknown
- 2020-04-13 MA MA056460A patent/MA56460A/fr unknown
- 2020-04-13 EP EP20766535.7A patent/EP3995822A4/de active Pending
- 2020-04-13 US US17/435,399 patent/US20220143609A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
WO2020177773A1 (zh) | 2020-09-10 |
EP3995822A4 (de) | 2022-10-05 |
CN109682878A (zh) | 2019-04-26 |
MA56460A (fr) | 2022-05-11 |
EP3995822A1 (de) | 2022-05-11 |
US20220143609A1 (en) | 2022-05-12 |
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