SG11202109034VA - Fermentative production of carbohydrates by microbial cells utilizing a mixed feedstock - Google Patents

Fermentative production of carbohydrates by microbial cells utilizing a mixed feedstock

Info

Publication number
SG11202109034VA
SG11202109034VA SG11202109034VA SG11202109034VA SG11202109034VA SG 11202109034V A SG11202109034V A SG 11202109034VA SG 11202109034V A SG11202109034V A SG 11202109034VA SG 11202109034V A SG11202109034V A SG 11202109034VA SG 11202109034V A SG11202109034V A SG 11202109034VA
Authority
SG
Singapore
Prior art keywords
carbohydrates
microbial cells
fermentative production
cells utilizing
mixed feedstock
Prior art date
Application number
SG11202109034VA
Inventor
Stefan Jennewein
Dirk Wartenberg
Original Assignee
Chr Hansen Hmo Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chr Hansen Hmo Gmbh filed Critical Chr Hansen Hmo Gmbh
Publication of SG11202109034VA publication Critical patent/SG11202109034VA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/02Monosaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004Monosaccharides having only carbon, hydrogen and oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016Disaccharides, e.g. lactose, lactulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1051Hexosyltransferases (2.4.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/04Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/18Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SG11202109034VA 2019-03-01 2020-02-28 Fermentative production of carbohydrates by microbial cells utilizing a mixed feedstock SG11202109034VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP19160379.4A EP3702468A1 (en) 2019-03-01 2019-03-01 Fermentative production of carbohydrates by microbial cells utilizing a mixed feedstock
PCT/EP2020/055299 WO2020178178A1 (en) 2019-03-01 2020-02-28 Fermentative production of carbohydrates by microbial cells utilizing a mixed feedstock

Publications (1)

Publication Number Publication Date
SG11202109034VA true SG11202109034VA (en) 2021-09-29

Family

ID=65861193

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202109034VA SG11202109034VA (en) 2019-03-01 2020-02-28 Fermentative production of carbohydrates by microbial cells utilizing a mixed feedstock

Country Status (10)

Country Link
US (1) US20220145342A1 (en)
EP (2) EP3702468A1 (en)
JP (1) JP2022522366A (en)
KR (1) KR20220012834A (en)
CN (1) CN113474463A (en)
AU (1) AU2020230967A1 (en)
BR (1) BR112021017091A2 (en)
MX (1) MX2021010527A (en)
SG (1) SG11202109034VA (en)
WO (1) WO2020178178A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022034075A1 (en) * 2020-08-10 2022-02-17 Inbiose N.V. Production of glcnac containing bioproducts in a cell
CN112175893B (en) * 2020-09-04 2022-06-17 清华大学 Recombinant microorganism for producing sialic acid and application thereof
DK181497B1 (en) * 2021-05-17 2024-03-12 Dsm Ip Assets Bv ENHANCING FORMATION OF THE HMOS LNT AND/OR LNnT BY MODIFYING LACTOSE IMPORT IN THE CELL
CN113234655B (en) * 2021-05-25 2023-09-26 北京化工大学 Recombinant bacterium for producing poly-3-hydroxybutyrate by utilizing xylose, and preparation method and application thereof
CN114317307B (en) * 2021-12-30 2024-05-10 广州智特奇生物科技股份有限公司 Genetically engineered bacterium capable of improving astaxanthin biosynthesis yield as well as construction method and application thereof
CN114686541A (en) * 2022-02-28 2022-07-01 北京焉支山科技有限公司 Biological enzyme synthesis method and application of cosmetic-grade hexose-6-phosphate composition
CN115074376B (en) * 2022-04-28 2023-11-14 福州大学 Method for efficiently synthesizing D-psicose by utilizing recombinant escherichia coli fermentation
WO2024020530A1 (en) * 2022-07-22 2024-01-25 Debut Biotechnology, Inc. Udp-sugar bioproduction using microorganism hosts

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2796082B1 (en) 1999-07-07 2003-06-27 Centre Nat Rech Scient PROCESS FOR PRODUCING OLIGOSACCHARIDES
JP2006508643A (en) 2002-07-01 2006-03-16 アーキオン ライフ サイエンシーズ エルエルシー ディー/ビー/エー バイオ−テクニカル リソーセズ ディビジョン Processes and materials for the production of glucosamine and N-acetylglucosamine
EP1789570A2 (en) 2004-09-17 2007-05-30 Neose Technologies, Inc. Production of oligosaccharides by microorganisms
KR101324369B1 (en) 2008-11-05 2013-11-01 미쓰이 가가쿠 가부시키가이샤 Bacterium capable of producing 2-deoxy-scyllo-inosose(doi), and process for producing 2-deoxy-scyllo-inosose(doi) by using same
JP5580408B2 (en) * 2009-06-08 2014-08-27 イェンネワイン バイオテクノロジー ゲーエムベーハー Synthesis of human milk oligosaccharides
EP2501820A4 (en) 2009-11-20 2014-05-14 Opx Biotechnologies Inc Methods, systems, and compositions for microbial bio-production of biomolecules using syngas components, or sugars, as feedstocks
EP3235907B1 (en) * 2010-07-12 2023-06-21 Inbiose N.V. Metabolically engineered organisms for the production of added value bio-products
US9029136B2 (en) * 2012-07-25 2015-05-12 Glycosyn LLC Alpha (1,2) fucosyltransferases suitable for use in the production of fucosylated oligosaccharides
EP2769726B1 (en) * 2013-02-21 2018-10-31 Jennewein Biotechnologie GmbH Synthetic or recombinant fucosylated Oligosaccarides for use in the treatment of infections
EP3461890A1 (en) * 2014-03-31 2019-04-03 Jennewein Biotechnologie GmbH Total fermentation of oligosaccharides
ITUB20152818A1 (en) * 2015-08-03 2017-02-03 Consorzio Univ Unifarm OPHTHALMIC FORMULATIONS BASED ON OLIGOSACCHARIDES
EP3473644A1 (en) 2017-10-17 2019-04-24 Jennewein Biotechnologie GmbH Fermentative production of n-acetylneuraminic acid
FI3575404T3 (en) 2018-05-28 2023-01-13 Fermentative production of sialylated saccharides
PL3620510T3 (en) 2018-09-06 2024-02-19 Chr. Hansen HMO GmbH Fermentative production of oligosaccharides by total fermentation utilizing a mixed feedstock

Also Published As

Publication number Publication date
WO2020178178A1 (en) 2020-09-10
EP3931340A1 (en) 2022-01-05
CN113474463A (en) 2021-10-01
KR20220012834A (en) 2022-02-04
AU2020230967A1 (en) 2021-08-26
BR112021017091A2 (en) 2021-11-03
US20220145342A1 (en) 2022-05-12
EP3702468A1 (en) 2020-09-02
JP2022522366A (en) 2022-04-18
MX2021010527A (en) 2021-10-01

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