SG11202109001UA - Process for polysorbate quantification in a sample involving lc-ms with an internal standard - Google Patents

Process for polysorbate quantification in a sample involving lc-ms with an internal standard

Info

Publication number
SG11202109001UA
SG11202109001UA SG11202109001UA SG11202109001UA SG11202109001UA SG 11202109001U A SG11202109001U A SG 11202109001UA SG 11202109001U A SG11202109001U A SG 11202109001UA SG 11202109001U A SG11202109001U A SG 11202109001UA SG 11202109001U A SG11202109001U A SG 11202109001UA
Authority
SG
Singapore
Prior art keywords
internal standard
sample involving
polysorbate
quantification
polysorbate quantification
Prior art date
Application number
SG11202109001UA
Inventor
Pierre Guibal
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of SG11202109001UA publication Critical patent/SG11202109001UA/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/62Detectors specially adapted therefor
    • G01N30/72Mass spectrometers
    • G01N30/7233Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/62Detectors specially adapted therefor
    • G01N2030/626Detectors specially adapted therefor calibration, baseline
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2560/00Chemical aspects of mass spectrometric analysis of biological material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Medicinal Preparation (AREA)
SG11202109001UA 2019-02-27 2020-02-27 Process for polysorbate quantification in a sample involving lc-ms with an internal standard SG11202109001UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP19305232 2019-02-27
PCT/EP2020/055191 WO2020174064A1 (en) 2019-02-27 2020-02-27 Process for polysorbate quantification in a sample involving lc-ms with an internal standard

Publications (1)

Publication Number Publication Date
SG11202109001UA true SG11202109001UA (en) 2021-09-29

Family

ID=65991721

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202109001UA SG11202109001UA (en) 2019-02-27 2020-02-27 Process for polysorbate quantification in a sample involving lc-ms with an internal standard

Country Status (13)

Country Link
US (1) US11796519B2 (en)
EP (1) EP3931572A1 (en)
JP (1) JP2022521628A (en)
KR (1) KR20210133222A (en)
CN (1) CN113490851A (en)
AU (1) AU2020229063A1 (en)
BR (1) BR112021016130A2 (en)
CA (1) CA3130408A1 (en)
IL (1) IL285735A (en)
MX (1) MX2021010357A (en)
SG (1) SG11202109001UA (en)
TW (1) TW202045927A (en)
WO (1) WO2020174064A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023117858A1 (en) 2021-12-20 2023-06-29 Boehringer Ingelheim International Gmbh Method for determining the degree of oxidative degradation of polysorbate 20 in aqueous formulations
CN115304227B (en) * 2022-07-15 2023-12-15 中国地质大学(武汉) Analysis method for molecular composition of soluble organic matters in sludge

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA05007653A (en) * 2003-01-17 2005-09-30 Danisco Method.
US9512463B2 (en) * 2011-11-08 2016-12-06 University Of Washington Methods and compositions for assaying the activity of one or more lysosomal enzymes
WO2013182217A1 (en) * 2012-04-27 2013-12-12 Sanofi-Aventis Deutschland Gmbh Quantification of impurities for release testing of peptide products
WO2013175312A1 (en) * 2012-05-23 2013-11-28 Glaxosmithkline Biologicals Sa Method for determining a concentration of a polysorbate species in a mixture
US20150141415A1 (en) * 2013-11-20 2015-05-21 Omonike Arike Olaleye Methionine Aminopeptidase Inhibitors for Treating Infectious Diseases
US10564076B2 (en) * 2015-06-16 2020-02-18 Agilent Technologies, Inc. Compositions and methods for analytical sample preparation
MX2019001572A (en) * 2016-08-15 2019-08-29 Genentech Inc Chromatography method for quantifying a non-ionic surfactant in a composition comprising the non-ionic surfactant and a polypeptide.
RU2670965C9 (en) * 2017-12-14 2018-11-21 Общество с ограниченной ответственностью "Международный Биотехнологический Центр "Генериум" Method of measuring number of polysorbate-80 with application of alkaline hydrolysis of sample with following hplc
KR20220147632A (en) * 2020-02-27 2022-11-03 리제너론 파아마슈티컬스, 인크. Activity-based host cell protein profiling

Also Published As

Publication number Publication date
CA3130408A1 (en) 2020-09-03
US11796519B2 (en) 2023-10-24
CN113490851A (en) 2021-10-08
TW202045927A (en) 2020-12-16
EP3931572A1 (en) 2022-01-05
JP2022521628A (en) 2022-04-11
US20220120720A1 (en) 2022-04-21
WO2020174064A1 (en) 2020-09-03
IL285735A (en) 2021-10-31
BR112021016130A2 (en) 2021-10-13
MX2021010357A (en) 2021-09-30
KR20210133222A (en) 2021-11-05
AU2020229063A1 (en) 2021-09-09

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