SG11202108365UA - Method of using track etched membranes for the filtration of biological fluids - Google Patents

Method of using track etched membranes for the filtration of biological fluids

Info

Publication number
SG11202108365UA
SG11202108365UA SG11202108365UA SG11202108365UA SG11202108365UA SG 11202108365U A SG11202108365U A SG 11202108365UA SG 11202108365U A SG11202108365U A SG 11202108365UA SG 11202108365U A SG11202108365U A SG 11202108365UA SG 11202108365U A SG11202108365U A SG 11202108365UA
Authority
SG
Singapore
Prior art keywords
filtration
biological fluids
track etched
etched membranes
membranes
Prior art date
Application number
SG11202108365UA
Inventor
Craig Robinson
Prity Bengani-Lutz
Original Assignee
Repligen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Repligen Corp filed Critical Repligen Corp
Publication of SG11202108365UA publication Critical patent/SG11202108365UA/en

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/18—Apparatus therefor
    • C—CHEMISTRY; METALLURGY
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    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/10—Separation or concentration of fermentation products
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    • B01D63/082—Flat membrane modules comprising a stack of flat membranes
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    • B01D39/14—Other self-supporting filtering material ; Other filtering material
    • B01D39/16—Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres
    • B01D39/1692—Other shaped material, e.g. perforated or porous sheets
    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01D67/0032—Organic membrane manufacture by inducing porosity into non porous precursor membranes by elimination of segments of the precursor, e.g. nucleation-track membranes, lithography or laser methods
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SG11202108365UA 2019-01-30 2020-01-30 Method of using track etched membranes for the filtration of biological fluids SG11202108365UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962798775P 2019-01-30 2019-01-30
PCT/US2020/015814 WO2020160220A1 (en) 2019-01-30 2020-01-30 Method of using track etched membranes for the filtration of biological fluids

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SG11202108365UA true SG11202108365UA (en) 2021-08-30

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US (1) US20220106554A1 (en)
EP (1) EP3917646A4 (en)
JP (1) JP2022520024A (en)
KR (1) KR20210121184A (en)
CN (1) CN113518655B (en)
AU (1) AU2020214316B2 (en)
CA (1) CA3127798A1 (en)
SG (1) SG11202108365UA (en)
WO (1) WO2020160220A1 (en)

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WO2023096779A1 (en) * 2021-11-24 2023-06-01 Corning Incorporated Advanced scalable extracellular vesicle (ev) isolation, separation, and concentration

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Publication number Priority date Publication date Assignee Title
FI103870B (en) * 1996-12-30 1999-10-15 Kari Aalto Method and apparatus for treating fluid
JP3881548B2 (en) * 1999-06-22 2007-02-14 ミリポア・コーポレイション Sealing device for filtration equipment
WO2004000444A1 (en) * 2002-06-19 2003-12-31 Northwest Biotherapeutics, Inc. Tangential flow filtration devices and methods for leukocyte enrichment
CN1759189A (en) * 2003-02-24 2006-04-12 Gtc生物治疗学公司 Methods of tangential flow filtration and an apparatus therefor
US8007670B2 (en) * 2005-09-09 2011-08-30 Tangenx Technology Corporation Laminated cassette device and methods for making same
JP2008221058A (en) * 2007-03-09 2008-09-25 Metawater Co Ltd Separation concentration apparatus of water microorganisms
JP2009113148A (en) * 2007-11-06 2009-05-28 Nomura Micro Sci Co Ltd Method of filtrating polishing sluryy, and method and device for recovering polishing material
PT106237B (en) * 2012-03-30 2015-03-19 Hovione Farmaci Ncia S A PRODUCTION OF SUBSTANCIALLY MONO-BUILT PARTICLES USING GRINDING AND MEMBRANE SEPARATION
WO2016200800A1 (en) * 2015-06-08 2016-12-15 Becton, Dickinson And Company Filtration cell and method for filtering a biological sample
CN106540325A (en) * 2015-09-21 2017-03-29 徐刚 The method and cell transplantation composite and its application of cell culture and transplanting
EP3354330A1 (en) * 2017-01-25 2018-08-01 Sartorius Stedim Biotech GmbH Automated modular filtration system
TWI675696B (en) * 2017-06-01 2019-11-01 美商Ｅｍｄ密理博公司 Tangential flow filtration device for perfusion applications

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