SG11202107978RA - Methods and system for the reconstruction of drug response and disease networks and uses thereof - Google Patents

Methods and system for the reconstruction of drug response and disease networks and uses thereof

Info

Publication number
SG11202107978RA
SG11202107978RA SG11202107978RA SG11202107978RA SG11202107978RA SG 11202107978R A SG11202107978R A SG 11202107978RA SG 11202107978R A SG11202107978R A SG 11202107978RA SG 11202107978R A SG11202107978R A SG 11202107978RA SG 11202107978R A SG11202107978R A SG 11202107978RA
Authority
SG
Singapore
Prior art keywords
reconstruction
methods
drug response
disease networks
networks
Prior art date
Application number
SG11202107978RA
Inventor
Brian Athey
Gerald Higgins
Alex Ade
Alexandr Kalinin
Narathip Reamaroon
James S Burns
Original Assignee
Univ Michigan Regents
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Michigan Regents filed Critical Univ Michigan Regents
Publication of SG11202107978RA publication Critical patent/SG11202107978RA/en

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Classifications

    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B45/00ICT specially adapted for bioinformatics-related data visualisation, e.g. displaying of maps or networks
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
    • G16B5/10Boolean models
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00ICT programming tools or database systems specially adapted for bioinformatics
    • G16B50/10Ontologies; Annotations
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/50ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medical Informatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Evolutionary Biology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Data Mining & Analysis (AREA)
  • Databases & Information Systems (AREA)
  • Bioethics (AREA)
  • Physiology (AREA)
  • Molecular Biology (AREA)
  • Primary Health Care (AREA)
  • Medicinal Chemistry (AREA)
  • Artificial Intelligence (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Software Systems (AREA)
  • Evolutionary Computation (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medical Treatment And Welfare Office Work (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG11202107978RA 2019-01-23 2020-01-22 Methods and system for the reconstruction of drug response and disease networks and uses thereof SG11202107978RA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962795710P 2019-01-23 2019-01-23
US201962795705P 2019-01-23 2019-01-23
PCT/US2020/014536 WO2020154356A1 (en) 2019-01-23 2020-01-22 Methods and system for the reconstruction of drug response and disease networks and uses thereof

Publications (1)

Publication Number Publication Date
SG11202107978RA true SG11202107978RA (en) 2021-08-30

Family

ID=69724089

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11202107994TA SG11202107994TA (en) 2019-01-23 2020-01-22 Pharmacogenomic decision support for modulators of the nmda, glycine, and ampa receptors
SG11202107978RA SG11202107978RA (en) 2019-01-23 2020-01-22 Methods and system for the reconstruction of drug response and disease networks and uses thereof

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG11202107994TA SG11202107994TA (en) 2019-01-23 2020-01-22 Pharmacogenomic decision support for modulators of the nmda, glycine, and ampa receptors

Country Status (8)

Country Link
US (3) US11984208B2 (en)
EP (2) EP3915121A1 (en)
JP (2) JP2022520009A (en)
CN (2) CN113597645A (en)
AU (2) AU2020210904A1 (en)
CA (2) CA3127607A1 (en)
SG (2) SG11202107994TA (en)
WO (2) WO2020154362A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20200357482A1 (en) * 2019-05-06 2020-11-12 MedWhatBio, Inc. Method and system for automating curation of genetic data
US11741557B2 (en) * 2020-01-01 2023-08-29 Rockspoon, Inc. Biomarker-based food item design system and method
US20220059204A1 (en) * 2020-08-21 2022-02-24 At&T Intellectual Property I, L.P. System and method for secure monitoring and delivery of medications
CN112382385A (en) * 2020-11-12 2021-02-19 山东中医药大学 Aura-free migraine auxiliary diagnosis algorithm based on 3D convolutional neural network
CN114758722B (en) * 2022-04-21 2024-06-28 湖南大学 Gene sequence interpolation method based on generation type countermeasure network
CN115101120B (en) * 2022-06-27 2024-04-16 山东大学 Corn alternative splicing isomer function prediction system based on data fusion
WO2024144380A1 (en) * 2022-12-30 2024-07-04 건국대학교 글로컬산학협력단 Method and device for predicting new drug repurposing candidate by ensemble of matched weighted-connection score calculated using machine learning-based meta-analysis
CN116467596B (en) * 2023-04-11 2024-03-26 广州国家现代农业产业科技创新中心 Training method of rice grain length prediction model, morphology prediction method and apparatus
CN116959561B (en) * 2023-09-21 2023-12-19 北京科技大学 Gene interaction prediction method and device based on neural network model
CN117788465B (en) * 2024-02-26 2024-05-28 中日友好医院(中日友好临床医学研究所) Method and device for associating local cerebral blood flow graph with transcription and cell characteristics

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4776146B2 (en) 2001-01-10 2011-09-21 ザ・ペン・ステート・リサーチ・ファンデーション Method and system for modeling cellular metabolism
US7585680B2 (en) * 2003-08-28 2009-09-08 Marshfield Medical Research And Education Foundation Method and device for monitoring medication usage
CA2759563A1 (en) 2009-04-20 2010-10-28 Fox Chase Cancer Center Rotamer libraries and methods of use thereof
MX2013001744A (en) * 2010-08-13 2013-06-28 Intellimedicine Inc System and methods for the production of personalized drug products.
EP2608122A1 (en) 2011-12-22 2013-06-26 Philip Morris Products S.A. Systems and methods for quantifying the impact of biological perturbations
EA201492178A1 (en) 2012-05-22 2015-12-30 Берг Ллк CELLULAR BASED CROSS ANALYSIS FOR IDENTIFICATION OF MARKERS INDUCED BY TOXICITY MEDICINES
US20140274764A1 (en) 2013-03-15 2014-09-18 Pathway Genomics Corporation Method and system to predict response to treatments for mental disorders
US10098854B2 (en) * 2014-08-13 2018-10-16 Janssen Pharmaceutica Nv Method for the treatment of depression
US10249389B2 (en) 2017-05-12 2019-04-02 The Regents Of The University Of Michigan Individual and cohort pharmacological phenotype prediction platform

Also Published As

Publication number Publication date
CA3127607A1 (en) 2020-07-30
CN113632174A (en) 2021-11-09
JP2022520009A (en) 2022-03-28
EP3915120A1 (en) 2021-12-01
CN113597645A (en) 2021-11-02
SG11202107994TA (en) 2021-08-30
CA3126828A1 (en) 2020-07-30
WO2020154362A1 (en) 2020-07-30
US11984208B2 (en) 2024-05-14
US20200234810A1 (en) 2020-07-23
AU2020210904A1 (en) 2021-08-05
AU2020212972A1 (en) 2021-08-05
WO2020154356A1 (en) 2020-07-30
US20200294623A1 (en) 2020-09-17
JP2022518272A (en) 2022-03-14
US20220020466A1 (en) 2022-01-20
EP3915121A1 (en) 2021-12-01

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