SG11202107656TA - Abc transporters for the high efficiency production of rebaudiosides - Google Patents

Abc transporters for the high efficiency production of rebaudiosides

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Publication number
SG11202107656TA
SG11202107656TA SG11202107656TA SG11202107656TA SG11202107656TA SG 11202107656T A SG11202107656T A SG 11202107656TA SG 11202107656T A SG11202107656T A SG 11202107656TA SG 11202107656T A SG11202107656T A SG 11202107656TA SG 11202107656T A SG11202107656T A SG 11202107656TA
Authority
SG
Singapore
Prior art keywords
rebaudiosides
high efficiency
abc transporters
efficiency production
production
Prior art date
Application number
SG11202107656TA
Inventor
Gale A Wichmann
Sean Lund
Joshua Lerman
Hanxiao Jiang
Yi Xiong
Original Assignee
Amyris Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amyris Inc filed Critical Amyris Inc
Publication of SG11202107656TA publication Critical patent/SG11202107656TA/en

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    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
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    • C12N9/0036—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6)
    • C12N9/0038—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6) with a heme protein as acceptor (1.6.2)
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    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C12N9/1062—Sucrose synthase (2.4.1.13)
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    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
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    • C12Y114/13—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with NADH or NADPH as one donor, and incorporation of one atom of oxygen (1.14.13)
    • C12Y114/13078—Ent-kaurene oxidase (1.14.13.78)
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    • C12Y114/13079—Ent-kaurenoic acid oxidase (1.14.13.79)
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    • C12Y114/13—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with NADH or NADPH as one donor, and incorporation of one atom of oxygen (1.14.13)
    • C12Y114/13158—Amorpha-4,11-diene 12-monooxygenase (1.14.13.158)
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    • C12Y204/00—Glycosyltransferases (2.4)
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    • C12Y204/01017—Glucuronosyltransferase (2.4.1.17)
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    • C12Y205/00—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5)
    • C12Y205/01—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5) transferring alkyl or aryl groups, other than methyl groups (2.5.1)
    • C12Y205/01001—Dimethylallyltranstransferase (2.5.1.1)
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    • C12Y205/01—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5) transferring alkyl or aryl groups, other than methyl groups (2.5.1)
    • C12Y205/01081—Geranylfarnesyl diphosphate synthase (2.5.1.81)
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    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/03—Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
    • C12Y402/03019—Ent-kaurene synthase (4.2.3.19)
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    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/03—Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
    • C12Y402/03024—Amorpha-4,11-diene synthase (4.2.3.24)
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    • C12Y505/00—Intramolecular lyases (5.5)
    • C12Y505/01—Intramolecular lyases (5.5.1)
    • C12Y505/01003—Tetrahydroxypteridine cycloisomerase (5.5.1.3)
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    • C12Y505/00—Intramolecular lyases (5.5)
    • C12Y505/01—Intramolecular lyases (5.5.1)
    • C12Y505/01013—Ent-copalyl diphosphate synthase (5.5.1.13)

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  • General Engineering & Computer Science (AREA)
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  • Biochemistry (AREA)
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  • Physics & Mathematics (AREA)
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  • Gastroenterology & Hepatology (AREA)
  • Botany (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
SG11202107656TA 2019-01-24 2020-01-23 Abc transporters for the high efficiency production of rebaudiosides SG11202107656TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962796228P 2019-01-24 2019-01-24
PCT/US2020/014859 WO2020154549A2 (en) 2019-01-24 2020-01-23 Abc transporters for the high efficiency production of rebaudiosides

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SG11202107656TA true SG11202107656TA (en) 2021-08-30

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US (1) US20220106619A1 (en)
EP (1) EP3914700A2 (en)
JP (1) JP7518838B2 (en)
KR (1) KR20210120027A (en)
CN (1) CN113631698A (en)
AU (1) AU2020211408A1 (en)
BR (1) BR112021014143A2 (en)
CA (1) CA3127249A1 (en)
MX (1) MX2021008747A (en)
SG (1) SG11202107656TA (en)
WO (1) WO2020154549A2 (en)

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CN118374427A (en) * 2024-05-07 2024-07-23 山东三元生物科技股份有限公司 Recombinant bacterium for catalyzing stevioside crude sugar to produce rebaudioside D and application thereof

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