SG11202107565RA - Novel uses of botulinum neurotoxin for the treatment of tremor - Google Patents

Novel uses of botulinum neurotoxin for the treatment of tremor

Info

Publication number
SG11202107565RA
SG11202107565RA SG11202107565RA SG11202107565RA SG11202107565RA SG 11202107565R A SG11202107565R A SG 11202107565RA SG 11202107565R A SG11202107565R A SG 11202107565RA SG 11202107565R A SG11202107565R A SG 11202107565RA SG 11202107565R A SG11202107565R A SG 11202107565RA
Authority
SG
Singapore
Prior art keywords
tremor
treatment
botulinum neurotoxin
novel uses
novel
Prior art date
Application number
SG11202107565RA
Inventor
Janos Csikos
Irena Pulte
Reinhard Hiersemenzel
Michael Althaus
Christiane Nalaskowski
David Simpson
Bahman Jabbari
Mandar Jog
Jack Lee
Original Assignee
Merz Pharma Gmbh & Co Kgaa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merz Pharma Gmbh & Co Kgaa filed Critical Merz Pharma Gmbh & Co Kgaa
Publication of SG11202107565RA publication Critical patent/SG11202107565RA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A61K38/4893—Botulinum neurotoxin (3.4.24.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/08—Clostridium, e.g. Clostridium tetani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Psychology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
SG11202107565RA 2019-02-21 2020-02-18 Novel uses of botulinum neurotoxin for the treatment of tremor SG11202107565RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP19158541 2019-02-21
PCT/EP2020/054201 WO2020169578A1 (en) 2019-02-21 2020-02-18 Novel uses of botulinum neurotoxin for the treatment of tremor

Publications (1)

Publication Number Publication Date
SG11202107565RA true SG11202107565RA (en) 2021-08-30

Family

ID=65520136

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202107565RA SG11202107565RA (en) 2019-02-21 2020-02-18 Novel uses of botulinum neurotoxin for the treatment of tremor

Country Status (12)

Country Link
US (1) US20220143157A1 (en)
EP (1) EP3927355A1 (en)
JP (1) JP2022521237A (en)
KR (1) KR20210130711A (en)
CN (1) CN113573727A (en)
AU (1) AU2020226945A1 (en)
BR (1) BR112021015480A2 (en)
CA (1) CA3130411A1 (en)
IL (1) IL285634A (en)
MX (1) MX2021009922A (en)
SG (1) SG11202107565RA (en)
WO (1) WO2020169578A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20240038789A (en) * 2022-05-24 2024-03-25 제이에이치엠 바이오파마슈티컬 (항저우) 씨오., 엘티디. Recombinant botulinum neurotoxin type A and method for producing the same
CN115894641B (en) * 2022-09-13 2023-09-29 君合盟生物制药(杭州)有限公司 Construction of A-type botulinum toxin mutant and genetically engineered bacterium thereof
WO2024049286A1 (en) * 2022-09-02 2024-03-07 (주)메디톡스 Botulinum toxin formulation having reduced resistance expression, and method related thereto

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19925739A1 (en) 1999-06-07 2000-12-21 Biotecon Ges Fuer Biotechnologische Entwicklung & Consulting Mbh Therapeutic with a botulinum neurotoxin
JP2007526212A (en) * 2003-04-25 2007-09-13 アラーガン、インコーポレイテッド Use of botulinum neurotoxin to alleviate various disorders
DE10333317A1 (en) 2003-07-22 2005-02-17 Biotecon Therapeutics Gmbh Formulation for protein medicines without the addition of human serum albumin (HSA)
GB2416122A (en) 2004-07-12 2006-01-18 Ipsen Ltd Botulinum neurotoxin composition
AU2005274822B2 (en) 2004-07-26 2008-10-30 Merz Pharma Gmbh & Co. Kgaa Therapeutic composition with a botulinum neurotoxin
GB2419526A (en) * 2004-10-28 2006-05-03 Ipsen Ltd Pharmaceutical composition containing botulinum neurotoxin
AR061669A1 (en) * 2006-06-29 2008-09-10 Merz Pharma Gmbh & Co Kgaa HIGH FREQUENCY THERAPY APPLICATION WITH BOTULIN TOXIN
AR069863A1 (en) * 2007-12-21 2010-02-24 Merz Pharma Gmbh & Co Kgaa EARLY ADMINISTRATION OF BOTULINAL TOXIN IN THE TREATMENT OF BRAIN ACCIDENTS AND INJURIES OF THE SPINAL MEDULA
ES2524312T3 (en) 2008-03-14 2014-12-05 Allergan, Inc. Assays of immunotype-based botulinum toxin serotype A activity
CA2831908C (en) 2011-03-31 2018-11-13 Medy-Tox Inc. Lyophilized preparation of botulinum toxin
RU2616281C2 (en) 2011-09-29 2017-04-13 СЕЛЛСНЭП, ЭлЭлСи Compositions and methods for toxigenic testing
CN105339790B (en) 2013-06-28 2018-04-17 莫茨制药有限及两合公司 For determining the tool and method of bioactivity of the neurotoxic peptide in cell
US10231665B2 (en) 2013-09-20 2019-03-19 Mddt Inc. Diagnosing and treating movement disorders
SG11201705019PA (en) 2014-12-23 2017-07-28 Merz Pharma Gmbh & Co Kgaa Botulinum toxin prefilled container
CN107206175B (en) 2015-02-03 2021-06-01 莫茨制药有限及两合公司 Botulinum toxin prefilled container
TWI737742B (en) 2016-06-22 2021-09-01 德商梅茲製藥有限兩合公司 Botulinum toxin prefilled syringe system, kit having the same and use thereof
KR101744900B1 (en) 2017-01-20 2017-06-08 주식회사 대웅 Stable Liquid Composition Comprising Botulinum Toxin

Also Published As

Publication number Publication date
KR20210130711A (en) 2021-11-01
IL285634A (en) 2021-09-30
WO2020169578A1 (en) 2020-08-27
CN113573727A (en) 2021-10-29
MX2021009922A (en) 2021-09-14
US20220143157A1 (en) 2022-05-12
CA3130411A1 (en) 2020-08-27
EP3927355A1 (en) 2021-12-29
JP2022521237A (en) 2022-04-06
BR112021015480A2 (en) 2021-10-05
AU2020226945A1 (en) 2021-07-22

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