SG11202106909YA - Pic1 variants with improved solubility and methods of using the same - Google Patents

Pic1 variants with improved solubility and methods of using the same

Info

Publication number
SG11202106909YA
SG11202106909YA SG11202106909YA SG11202106909YA SG11202106909YA SG 11202106909Y A SG11202106909Y A SG 11202106909YA SG 11202106909Y A SG11202106909Y A SG 11202106909YA SG 11202106909Y A SG11202106909Y A SG 11202106909YA SG 11202106909Y A SG11202106909Y A SG 11202106909YA
Authority
SG
Singapore
Prior art keywords
pic1
variants
methods
same
improved solubility
Prior art date
Application number
SG11202106909YA
Inventor
Neel Krishna
Kenji Cunnion
Original Assignee
Realta Holdings Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Realta Holdings Llc filed Critical Realta Holdings Llc
Publication of SG11202106909YA publication Critical patent/SG11202106909YA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1725—Complement proteins, e.g. anaphylatoxin, C3a or C5a
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/19—Platelets; Megacaryocytes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Transplantation (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SG11202106909YA 2019-02-15 2020-02-13 Pic1 variants with improved solubility and methods of using the same SG11202106909YA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962806432P 2019-02-15 2019-02-15
US201962949181P 2019-12-17 2019-12-17
PCT/US2020/018045 WO2020168036A1 (en) 2019-02-15 2020-02-13 Pic1 variants with improved solubility and methods of using the same

Publications (1)

Publication Number Publication Date
SG11202106909YA true SG11202106909YA (en) 2021-07-29

Family

ID=72044620

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202106909YA SG11202106909YA (en) 2019-02-15 2020-02-13 Pic1 variants with improved solubility and methods of using the same

Country Status (11)

Country Link
US (1) US20220096592A1 (en)
EP (1) EP3924057A4 (en)
JP (1) JP2022520430A (en)
KR (1) KR20210129104A (en)
CN (1) CN113474050A (en)
AU (1) AU2020221342A1 (en)
CA (1) CA3127253A1 (en)
IL (1) IL285572A (en)
MX (1) MX2021009783A (en)
SG (1) SG11202106909YA (en)
WO (1) WO2020168036A1 (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10005818B2 (en) * 2010-07-21 2018-06-26 Realta Holdings, Llc Derivative peptide compounds and methods of use
CA2987141A1 (en) * 2015-06-26 2016-12-29 Eastern Virginia Medical School Synthetic peptide compounds and methods of use

Also Published As

Publication number Publication date
CA3127253A1 (en) 2020-08-20
US20220096592A1 (en) 2022-03-31
JP2022520430A (en) 2022-03-30
MX2021009783A (en) 2021-09-08
IL285572A (en) 2021-09-30
EP3924057A4 (en) 2022-10-26
KR20210129104A (en) 2021-10-27
WO2020168036A1 (en) 2020-08-20
AU2020221342A1 (en) 2021-07-15
EP3924057A1 (en) 2021-12-22
CN113474050A (en) 2021-10-01

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